Native Malate dehydrogenase from Thermophillic bacteria
1 Inquiries
9001-64-3
Yes
2026-11-22
Coenzymes,Inhibito,Enzymes,Zymogens,Substrates,Native Microorganism Creatine Amidinohydrolase
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Product Details
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Seller Information
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Inquiry History
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Description
ProductName Native Malate dehydrogenase from Thermophillic bacteria Cat No DIA-401 Description Malate dehydrogenase is an enzyme in the citric acid cycle that catalyzes the conversion of malate into oxaloacetate (using NAD+) and vice versa (this is a reversible reaction). Malate dehydrogenase is not to be confused with malic enzyme, which catalyzes the conversion of malate to pyruvate producing NADPH. Malate dehydrogenase is also involved in gluconeogenesis, the synthesis of glucose from smaller molecules. Pyruvate in the mitochondria is acted upon by pyruvate carboxylase to form oxaloacetate, a citric acid cycle intermediate. In order to get the oxaloacetate out of the mitochondria, malate dehydrogenase reduces it to malate, and it then traverses the inner mitochondrial membrane. Once in the cytosol, the malate is oxidized back to oxaloacetate by cytosolic malate dehydrogenase. Finally, phosphoenol-pyruvate carboxy kinase (PEPCK) converts oxaloacetate to phosphoenol pyruvate. Abbr MDH, Native (Thermophillic bacteria) Alias MDH Source Thermophillic bacteria Applications Diagnostic test and biosensors; NADH recycling. This enzyme is a potential candidate for biocatalysis, suitable for pharmaceutical development / manufacturing. Form Frozen Liquid Enzyme Commission Number EC 1.1.1.37 CAS No 9001-64-3 Unit Definition One unit of enzyme is defined as the amount catalyzing the oxidation of 1μmol NADH (ε= 6.22 mM-1cm-1) per min at 37°C. Optimum pH 8.5 Thermal stability ~100% stability after 1 hour at 85°C Storage Store at -20°C Buffer 50 mM Tris-HCl (pH 8.0) / 50 mM NaCl Synonyms malic dehydrogenase; L-malate dehydrogenase; NAD-L-malate dehydrogenase; malic acid dehydrogenase; NAD-dependent malic dehydrogenase; NAD-malate dehydrogenase; NAD-malic dehydrogenase; malate NAD dehydrogenase; NAD-dependent malate dehydrogenase; NAD-sp; ECific malate dehydrogenase; NAD-linked malate dehydrogenase; MDH; L-malate-NAD+ oxidoreductase; S-malate: NAD+ oxidoreductase; EC 1.1.1.37; Malate Dehydrogenase category Enzyme(c2117) cas_num 9001-64-3 ECHEMI Editorial ReferencePowderBasic Info-
Product Name:
Malate dehydrogenase (NAD)
Other Name:Malate dehydrogenase (NAD);Dehydrogenase,malate;E.C. 1.1.1.37;Malate dehydrogenase;L-Malate dehydrogenase;Malic dehydrogenase;L-Malate:NAD oxidoreductase;EC 1.1.1.37;Nicotinamide adenine dinucleotide malate dehydrogenase;NAD-L-malate dehydrogenase;Malic acid dehydrogenase;Malate dehydrogenase (cytoplasmic);Malate dehydrogenase (NAD);Malate-NAD oxidoreductase;NAD-dependent malic dehydrogenase;NAD-malate dehydrogenase;NAD-malic dehydrogenase;Malate (NAD) dehydrogenase;NAD-dependent malate dehydrogenase;NAD-specific malate dehydrogenase;Malate dehydrogenase (E.C. 1.1.1.37);NAD+-specific malate dehydrogenase;L-Malate:NAD+ oxidoreductase;Malate dehydrogenase (NADH-dependent);NADH-malate dehydrogenase;NAD-linked malate dehydrogenase;Malic dehydrogenase (EC 1.1.1.37);Malate dehydrogenase NAD-dependent;MDH;Proteins,AIP 37/6 (adrenergically induced protein,37,000-mol.-wt.,pI 6.0);Proteins,AIP 37/6;Proteins,adrenergically induced,37,000-mol.-wt.,pI 6.0;AIP 37/6 proteins;Adrenergically induced proteins,37 kDa,pI 6.0;37,000-Mol.-wt. adrenergically induced proteins,pI 6.0;PI 6.0 adrenergically induced proteins,37,000-mol.-wt.;MAD 211;L-Malate dehydrogenase (E.C. 1.1.1.37)
CAS No.:9001-64-3
Exact Mass:226.106583
EC Number:232-622-5
HScode:35079090
Categories:
Characteristics-
XLogP3:
-2.17
Appearance:slightly beige suspension
Density:1.4±0.1 g/cm3
Boiling Point:656.2±55.0 °C at 760 mmHg
Flash Point:350.7±31.5 °C
Refractive Index:1.591
Storage Conditions:2-8°C
Hazard IdentificationClassification of the substance or mixture
Respiratory sensitization, Category 1
GHS label elements, including precautionary statements
Pictogram(s) 
Signal word Danger
Hazard statement(s) H334 May cause allergy or asthma symptoms or breathing difficulties if inhaled
Precautionary statement(s) Prevention P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P284 [In case of inadequate ventilation] wear respiratory protection.
Response P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing.
P342+P316 If experiencing respiratory symptoms: Get emergency medical help immediately.
Storage none
Disposal P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.
Other hazards which do not result in classification
no data available
Handling and StoragePrecautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.
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Seller Information
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Business Type:
Manufactory
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Main Products:
Coenzymes,Inhibito,Enzymes,Zymogens,Substrates,Native Microorganism Creatine Amidinohydrolase
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Location:
Shirley, New York 11967, USA
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Payment Terms:
TT against copy of documents,D/P
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Average lead Time:
15 days
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Total Annual Revenue:
$1 million-$2.5 million
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Year of Establishment:
2004
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Inquiry History1 Inquiries
Country Product Purchase Quantity Date Posted 
Italy
Malate dehydrogenase (NAD)
2000 Jan 16, 2024 Post an enquiry for this product
