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12-ALPHA-HYDROXYSTEROID DEHYDROGENASE
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Native Bacillus sphaericus 12α-Hydroxysteroid Dehydrogenase
Native Bacillus sphaericus 12α-Hydroxysteroid Dehydrogenase
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CAS No.:
61642-40-8
Price valid (until):
2026-09-27
Company Type:
Manufactory
Location:
United States
Qualification:
Main Products:
Coenzymes,Inhibito,Enzymes,Zymogens,Substrates,Native Microorganism Creatine Amidinohydrolase
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Product Description
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Description
ProductName Native Bacillus sphaericus 12α-Hydroxysteroid Dehydrogenase Cat No NATE-0001 Description In enzymology, a 12alpha-hydroxysteroid dehydrogenase (EC 1.1.1.176) is an enzyme that catalyzes the chemical reaction:3alpha,7alpha,12alpha-trihydroxy-5beta-cholanate + NADP+↔ 3alpha,7alpha-dihydroxy-12-oxo-5beta-cholanate + NADPH + H+. Thus, the two substrates of this enzyme are 3alpha,7alpha,12alpha-trihydroxy-5beta-cholanate and NADP+, whereas its 3 products are 3alpha,7alpha-dihydroxy-12-oxo-5beta-cholanate, NADPH, and H+. This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. This enzyme is involved in a metabolic pathway that degrades bile acids into cholesterol. Abbr 12α-Hydroxysteroid Dehydrogenase, Native (Bacillus sphaericus) Source Bacillus sphaericus Form lyophilized powder Enzyme Commission Number EC 1.1.1.176 Activity 150-350 units/mg protein (Lowry) CAS No 61642-40-8 Unit Definition One unit will oxidize 1.0 μmole of deoxycholic acid to 12-ketodeoxycholic acid per min at pH 8.0 at 37°C. Storage −20°C Synonyms EC 1.1.1.176; 61642-40-8; 12α Hydroxysteroid Dehydrogenase; 12alpha-hydroxy steroid dehydrogenase; NAD+-dependent 12alpha-hydroxysteroid dehydrogenase; NADP+-12alpha-hydroxysteroid dehydrogenase; 12-α-Hydroxysteroid Dehydrogenase; 12alpha-hydroxysteroid:NADP+ 12-oxidoreductase category Specialty Chemicals(c26) cas_num 61642-40-8 Basic Info-
Product Name:
12-ALPHA-HYDROXYSTEROID DEHYDROGENASE
Other Name:12ALPHA-HSDH;12-ALPHA-HYDROXYSTEROID DEHYDROGENASE;12ALPHA-HYDROXYSTEROID:NADP+-OXIDOREDUCTASE;EC 1.1.1.176;12A-HYDROXYSTEROID DEHYDROGENASE FROM*BA CILLUS SPHA;FromClostridiumspec.;12α-HydroxysteroidDehydrogenasefromBacillussphaericus;12α-HydroxysteroidDehydrogenasefromClostridiumsp.
CAS No.:61642-40-8
Categories:
Characteristics-
Storage Conditions:
−20°C
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Seller Information
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Business Type:
Manufactory
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Main Products:
Coenzymes,Inhibito,Enzymes,Zymogens,Substrates,Native Microorganism Creatine Amidinohydrolase
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Location:
Shirley, New York 11967, USA
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Payment Terms:
TT against copy of documents,D/P
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Average lead Time:
15
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Total Annual Revenue:
$1 million-$2.5 million
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Year of Establishment:
2004
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