Native Rhodococcus rhodochrous Epoxide Hydrolase
9048-63-9
Yes
2026-11-12
Coenzymes,Inhibito,Enzymes,Zymogens,Substrates,Native Microorganism Creatine Amidinohydrolase
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Product Description
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Seller Information
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Description
ProductName Native Rhodococcus rhodochrous Epoxide Hydrolase Cat No NATE-0449 Description Epoxide hydrolase (also known as epoxide hydratase) functions in detoxification during drug metabolism. It converts epoxides to trans-dihydrodiols, which can be conjugated and excreted from the body. Epoxides result from the degradation of aromatic compounds. Deficiency in this enzyme in patients receiving aromatic-type anti-epileptic drugs such as phenytoin is reported to lead to DRESS syndrome. Epoxides are significant as cytochrome P450 oxidase metabolites of unsaturated carbon-carbon bonds, but are also mutagenic. Epoxide hydrolase is present in large quantity on endoplasmic reticulum. Abbr mEH, Native (Rhodococcus rhodochrous) Alias mEH Source Rhodococcus rhodochrous Form lyophilized powder, beige Enzyme Commission Number EC 3.3.2.3 Activity > 0.5 U/g CAS No 9048-63-9 Unit Definition 1 U corresponds to the amount of enzymes which hydrolizes 1 μmol (S)-NEPC [(2S,3S)-trans-3-phenyl-2-oxiranylmethyl-4-nitrophenyl carbonate] per minute at pH 8.0 and 25°C Storage −20°C Warnings Asymmetric hydrolysis of epoxides to optically active diols Synonyms EC 3.3.2.3; epoxide hydratase; epoxide hydratase (ambiguous); microsomal epoxide hydratase; epoxide hydrase; microsomal epoxide hydrase; arene-oxide hydratase (ambiguous); benzo[a]pyrene-4,5-oxide hydratase; benzo (a)pyrene-4,5-epoxide hydratase; aryl epoxide hydrase (ambiguous); cis-epoxide hydrolase; mEH; 9048-63-9 category Specialty Chemicals(c26) cas_num 9048-63-9 Basic Info-
Product Name:
EC3.3.2.3
Other Name:EC 3.3.2.3;EPOXIDE HYDROLASE;Hydratase, epoxide;EPOXIDE HYDROLASE MICROSOMES, HUMAN;EPOXIDE HYDROLASE, ASPERGILLUS NIGER;Epoxide Hydrolase Rhodococcus rhodochrous;EPOXIDE HYDROLASE, AGROBACTERIUM RADIOBACTER;epoxide hydrolase from rhodococcus rhodochrous;EPOXIDE-HYDROLASE FROM RHODOCOCCUSRHODOC HROUS, ~1 U/G;EPOXIDE HYDROLASE, ASPERGILLUS NIGER, REC., FROM E. COLI*
CAS No.:9048-63-9
Categories:
Characteristics-
Appearance:
light brown powder
Storage Conditions:2-8°C
Hazard IdentificationClassification of the substance or mixture
Skin sensitization, Category 1
Respiratory sensitization, Category 1
GHS label elements, including precautionary statements
Pictogram(s)
Signal word Danger
Hazard statement(s) H317 May cause an allergic skin reaction
H334 May cause allergy or asthma symptoms or breathing difficulties if inhaled
Precautionary statement(s) Prevention P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P272 Contaminated work clothing should not be allowed out of the workplace.
P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...
P284 [In case of inadequate ventilation] wear respiratory protection.
Response P302+P352 IF ON SKIN: Wash with plenty of water/...
P333+P317 If skin irritation or rash occurs: Get medical help.
P321 Specific treatment (see ... on this label).
P362+P364 Take off contaminated clothing and wash it before reuse.
P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing.
P342+P316 If experiencing respiratory symptoms: Get emergency medical help immediately.
Storage none
Disposal P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.
Other hazards which do not result in classification
no data available
Handling and StoragePrecautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.
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Seller Information
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Business Type:
Manufactory
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Main Products:
Coenzymes,Inhibito,Enzymes,Zymogens,Substrates,Native Microorganism Creatine Amidinohydrolase
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Location:
Shirley, New York 11967, USA
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Payment Terms:
TT against copy of documents,D/P
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Average lead Time:
15 days
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Total Annual Revenue:
$1 million-$2.5 million
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Year of Establishment:
2004
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Country Product Purchase Quantity Date Posted Post an enquiry for this product