Native Vibrio cholerae Neuraminidase
9001-67-6
Yes
2026-11-14
Coenzymes,Inhibito,Enzymes,Zymogens,Substrates,Native Microorganism Creatine Amidinohydrolase
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Product Description
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Seller Information
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Description
ProductName Native Vibrio cholerae Neuraminidase Cat No NATE-0481 Description Neuraminidase enzymes are glycoside hydrolase enzymes (EC 3.2.1.18) that cleave the glycosidic linkages of neuraminic acids. Neuraminidase enzymes are a large family, found in a range of organisms. The best-known neuraminidase is the viral neuraminidase, a drug target for the prevention of the spread of influenza infection. The viral neuraminidases are frequently used as antigenic determinants found on the surface of the Influenza virus. Some variants of the influenza neuraminidase confer more virulence to the virus than others. Other homologs are found in mammalian cells, which have a range of functions. At least four mammalian sialidase homologs have been described in the human genome (see NEU1, NEU2, NEU3, NEU4). Abbr Neuraminidase, Native (Vibrio cholerae) Alias sialidase Source Vibrio cholerae Applications Neurminidase is used as a cell-surface probe for glyc oconjugate distribution and in substrate specificity studies. Neuraminidase from Vibrio cholerae has been used in a study to assess its role in the binding and uptake of cholera toxin by susceptible cells. It has also been used in a study to investigate the preparation of a sodium substrate and its use in a fluorometric assay of neuraminidase. Product Overview Neuraminidase enzymes are glycoside hydrolase enzymes that catalyze hydrolysis of terminal sialic acid residues. The most well-known are the viral nearamidases, which promote influenza virus release. Form Type I, buffered aqueous solution; Aqueous solution, pH 5.5, containing 0.15 M NaCl and 4 mM CaCl2; Type II, buffered aqueous solution, Solution in 50 mM sodium acetate, pH 5.5, containing 0.15 M sodium chloride and 4 mM calcium chloride; Type III, sterile filtered, aqueous solution, pH 5.5, 0.15 M NaCl and 4 mM CaCl2. Enzyme Commission Number EC 3.2.1.18 Activity Type I, 1-5 units/mg protein (Lowry, using NAN-lactose); Type II, 8-24 units/mg protein (Lowry, using NAN-lactose); Type III, > 1.5 units/mg protein. CAS No 9001-67-6 Unit Definition One unit will liberate 1.0 μmole of N-acetylneuraminic acid per min at pH 5.0 at 37°C using NAN-lactose or bovine submaxillary mucin, unless otherwise specified. Prices based on units using NAN-lactose as substrate. Storage 2-8°C Warnings Chromatographically purified. Pathway Other glycan degradation, organism-specific biosystem (from KEGG) Other glycan degradation, conserved biosystem (from KEGG) Vibrio cholerae infection, organism-specific biosystem (from KEGG) Vibrio cholerae infection, conserved biosystem (from KEGG) Synonyms neuraminidase; sialidase; α-neuraminidase; acetylneuraminidase; exo-α-sialidase; EC 3.2.1.18; 9001-67-6 category Amino Acids and Proteins(c1511) cas_num 9001-67-6 Basic Info-
Product Name:
Neuraminidase
Other Name:Neuraminidase;E.C. 3.2.1.18;Sialidase;α-Neuraminidase;EC 3.2.1.18;Acetylneuraminidase;Sialidase (EC 3.2.1.18);Arylneuraminidase;N-Acylneuraminyl hydrolase;N-Acetylneuraminidase;Exo-α-sialidase;Parasite-derived mimic of neurotrophic factors;ALP Separator;Neuraminidase A;Neuraminidase B;α-2-3,6,8-Neuraminidase;exo-α-Sialidase;Neuraminidase,α-;Sialidase,exo-;Neuraminidase,N-acetyl;Sialidase,α-;Sialidase A;9014-31-7
CAS No.:9001-67-6
Exact Mass:226.106583
EC Number:232-624-6
Categories:
Characteristics-
XLogP3:
-2.17
Appearance:white lyophilized powder
Density:1.4±0.1 g/cm3
Boiling Point:656.2±55.0 °C at 760 mmHg
Flash Point:350.7±31.5 °C
Refractive Index:1.591
Water Solubility:soluble in water or 10mM phosphate buffer, pH 6.0
Storage Conditions:2-8°C
Hazard IdentificationClassification of the substance or mixture
Respiratory sensitization, Category 1
GHS label elements, including precautionary statements
Pictogram(s) 
Signal word Danger
Hazard statement(s) H334 May cause allergy or asthma symptoms or breathing difficulties if inhaled
Precautionary statement(s) Prevention P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P284 [In case of inadequate ventilation] wear respiratory protection.
Response P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing.
P342+P316 If experiencing respiratory symptoms: Get emergency medical help immediately.
Storage none
Disposal P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.
Other hazards which do not result in classification
no data available
Handling and StoragePrecautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.
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Seller Information
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Business Type:
Manufactory
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Main Products:
Coenzymes,Inhibito,Enzymes,Zymogens,Substrates,Native Microorganism Creatine Amidinohydrolase
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Location:
Shirley, New York 11967, USA
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Payment Terms:
TT against copy of documents,D/P
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Average lead Time:
15 days
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Total Annual Revenue:
$1 million-$2.5 million
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Year of Establishment:
2004
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Country Product Purchase Quantity Date Posted Post an enquiry for this product
