Native Rabbit Creatine Phosphokinase
9001-15-4
Yes
2026-11-15
Coenzymes,Inhibito,Enzymes,Zymogens,Substrates,Native Microorganism Creatine Amidinohydrolase
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Product Description
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Seller Information
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Description
ProductName Native Rabbit Creatine Phosphokinase Cat No NATE-0138 Description Creatine kinase plays a key role in the energy metabolism of cells with intermittently high and fluctuating energy requirements. Examples of such cells include cardiac or skeletal muscle cells and neural tissues of brain and retina. The enzyme catalyzes the reversible transfer of the phosphoryl group from phosphorylcreatine to ADP, in order to generate ATP.1 The molecular mass of the protein is found to be approximately 80 kDa Da. It is made up of 2 subunits, each having a molecular weight of 40 kDa ± 2000. The lighter subunit is present in larger amounts. Abbr CK, Native (Rabbit) Alias CK; CPK; MM-CK; MB-CK; BB-CK Source Rabbit muscle Species Rabbit Applications Molecular Weight: ~81 kDa Creatine Phosphokinase is a dimer composed predominantly of the skeletal muscle derived homodimer (MM). CK also exists as a heterodimer (MB) particularly in the myocardium. CK derived from brain tissue consists mainly of the brain source homodimer (BB). The amino acid sequences of the M chain and B chains are about 80% homologous. From the sequence, the molecular weight of the M chain is 43,112. Product Overview Protein determined by biuret. Form salt-free, lyophilized powder. Enzyme Commission Number EC 2.7.3.2 Activity > 150 units/mg protein CAS No 9001-15-4 Unit Definition One unit will transfer 1.0 μmole of phosphate from phosphocreatine to ADP per min at pH 7.4 at 30°C. Optimum pH pH 8.8-9.0 for the forward reaction and pH 6.0-7.0 for the reverse reaction. Storage −20°C Buffer 0.25 M glycyl-glycine, pH 7.4: soluble 5.0 mg/mL, clear, colorless to slightly yellow Inhibitors ADP is a strong inhibitor of the forward reaction competing with ATP. Divalent cations such as Ca2+ (Ki=4.5 mM), Zn2+ and Cu2+ inhibit CK by competing with Mg2+. Other inhibitors include acetate, acetylsalicylic acid, adenosine, p-aminosalicylic acid, AMP, benzoic acid, bicarbonate, bromide, chloride, p-Chloromercuribenzoic acid, ethylene oxide, 2,4-fluorodinitrobenzene, iodide, malonic acid, NAD, nitrate, phosphate, pyrophosphate, salicylic acid, sulfate, sulfite, thyroxine, trichloroacetate, L-triiodothyroxine, L-triiodothyronine, and tripolyphosphate. Synonyms EC 2.7.3.2; ATP:creatine phosphotransferase; CK; CPK; MM-CK; MB-CK; BB-CK; creatine phosphokinase; creatine phosphotransferase; phosphocreatine kinase; adenosine triphosphate-creatine transphosphorylase; Mi-CK; CK-BB; CK-MM; CK-MB; CKMiMi; MiMi-CK; 9001-15-4 category Enzymes and Coenzymes Drugs(c1513) cas_num 9001-15-4 Basic Info-
Product Name:
Creatine kinase
Other Name:Creatine kinase;Kinase (phosphorylating),creatine;E.C. 2.7.3.2;Creatine phosphokinase;EC 2.7.3.2;Creatine phosphotransferase;Phosphocreatine kinase;ATP:creatine phosphotransferase;CK;ATP:creatine N-phosphotransferase;Creatinine phosphokinase;Creatine phosphotransferases;Creatine phosphokinases;Creatine kinases;Creatinine phosphokinases;Phosphocreatine kinases;9026-66-8;139946-34-2;139946-37-5
CAS No.:9001-15-4
Exact Mass:446.007233
EC Number:232-585-5
HScode:35079090
Categories:
Characteristics-
XLogP3:
4.44
Appearance:white salt-free, lyophilized powder
Density:1.7±0.1 g/cm3
Boiling Point:629.9±55.0 °C at 760 mmHg
Flash Point:334.8±31.5 °C
Refractive Index:1.722
Water Solubility:0.25 M glycyl-glycine, pH 7.4: soluble5.0mg/mL, clear, colorless to slightly yellow
Storage Conditions:−20°C
Hazard IdentificationClassification of the substance or mixture
no data available
GHS label elements, including precautionary statements
Pictogram(s) no data available Signal word no data available
Hazard statement(s) no data available
Precautionary statement(s) Prevention no data available
Response no data available
Storage no data available
Disposal no data available
Other hazards which do not result in classification
no data available
Handling and StoragePrecautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.
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Seller Information
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Business Type:
Manufactory
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Main Products:
Coenzymes,Inhibito,Enzymes,Zymogens,Substrates,Native Microorganism Creatine Amidinohydrolase
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Location:
Shirley, New York 11967, USA
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Payment Terms:
TT against copy of documents,D/P
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Average lead Time:
15 days
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Total Annual Revenue:
$1 million-$2.5 million
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Year of Establishment:
2004
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Country Product Purchase Quantity Date Posted Post an enquiry for this product
