Native Actinobacillus sp. Creatinase
37340-58-2
2026-09-10
Coenzymes,Inhibito,Enzymes,Zymogens,Substrates,Native Microorganism Creatine Amidinohydrolase
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Product Description
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Seller Information
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Description
ProductName Native Actinobacillus sp. Creatinase Cat No NATE-0160 Description In enzymology, a creatinase (EC 3.5.3.3) is an enzyme that catalyzes the chemical reaction:creatine + H2O↔ sarcosine + urea. Thus, the two substrates of this enzyme are creatine and H2O, whereas its two products are sarcosine and urea. This enzyme belongs to the family of hydrolases, those acting on carbon-nitrogen bonds other than peptide bonds, specifically in linear amidines. Creatinase accelerates the conversion reaction of creatine and water molecule to sarcosine and urea. It always acts in homodimer state and is induced by choline chloride. Abbr Creatinase, Native (Actinobacillus sp.) Alias creatinase Source Actinobacillus sp. Applications Creatinase mixed with sarcosine oxidase may be used to determine the level of creatine in different pH, temperature, enzyme ratio, and buffer concentration. It may also be used to determine the plasma creatinine level by using a centrifugal analyser. Form Lyophilized powder containing sugars and EDTA as stabilizers Enzyme Commission Number EC 3.5.3.3 Activity 20-40 units/mg protein CAS No 37340-58-2 Molecular Weight mol wt ~100 kDa Isoelectric point 4.6 ± 0.1 pH Stability pH 5.5 − 9.0 (25°C, 16hr) Michaelis Constant 1.9 x 10‾2M (Creatine) Structure 2 subunits per mole of enzyme Unit Definition One unit will hydrolyze 1.0 μmole of creatine to urea and sarcosine per min at pH 7.5 at 37°C. Optimum pH 8 Optimum temperature 40°C Thermal stability Below 50°C (pH 7.5, 30 min) Storage −20°C Inhibitors Cu++, Hg++, Ag+ Synonyms Creatine amidinohydrolase; creatinase; 37340-58-2; EC 3.5.3.3 category Amino Acids and Proteins(c1511) cas_num 37340-58-2 Basic Info-
Product Name:
Creatinase
Other Name:Creatinase;Creatine amidinohydrolase;E.C. 3.5.3.3;EC 3.5.3.3;Creatine aminohydrolase;Creatine amidinohydrolases;Creatinases
CAS No.:37340-58-2
EC Number:253-471-1
Categories:
Characteristics-
Appearance:
white lyophilized powder
Storage Conditions:2-8°C
Hazard IdentificationClassification of the substance or mixture
no data available
GHS label elements, including precautionary statements
Pictogram(s) no data available Signal word no data available
Hazard statement(s) no data available
Precautionary statement(s) Prevention no data available
Response no data available
Storage no data available
Disposal no data available
Other hazards which do not result in classification
no data available
Handling and StoragePrecautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.
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Seller Information
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Business Type:
Manufactory
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Main Products:
Coenzymes,Inhibito,Enzymes,Zymogens,Substrates,Native Microorganism Creatine Amidinohydrolase
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Location:
Shirley, New York 11967, USA
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Payment Terms:
TT against copy of documents,D/P
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Average lead Time:
15
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Total Annual Revenue:
$1 million-$2.5 million
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Year of Establishment:
2004
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