Native Bovine Phosphodiesterase 3',5'-Cyclic Nucleotide Activator-deficient
9040-59-9
Package size based on activated units
2026-09-21
Coenzymes,Inhibito,Enzymes,Zymogens,Substrates,Native Microorganism Creatine Amidinohydrolase
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Product Description
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Seller Information
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Description
ProductName Native Bovine Phosphodiesterase 3',5'-Cyclic Nucleotide Activator-deficient Cat No NATE-0514 Description Hydrolyzes the 3',5'-phosphodiester bond in cyclic nucleotide monophosphates, such as cAMP and cGMP, to the corresponding nucleotide 5'-monophosphate. Abbr PDE, Native (Bovine) Alias PDE Source Bovine heart Species Bovine Applications Cyclic nucleotide phosphodiesterase has been investigated for its mechanism of activation as a function of calmodulin and Ca2+. It has also been used in a study to show that the binding of trifluoperazine to the activator of cyclic nucleotide phosphodiesterase increases the activity by over 10-fold. For use in calmodulin (P 0270) assay. Activity is reduced to <50% without calmodulin present. Package Package size based on activated units Form lyophilized powder (contains imidazole buffer salts and magnesium sulfate) Enzyme Commission Number EC 3.1.4.17 Activity >0.1 units/mg protein (with added activator) CAS No 9040-59-9 Molecular Weight mol wt ~60 kDa Unit Definition One unit will hydrolyze 1.0 μmole of 3':5',-cyclic-AMP to 5'-AMP per min at pH 7.5 at 30°C. Storage −20°C Buffer Reconstitute with 50% glycerol. The total activated units of enzyme will remain constant for at least 5 days when stored at −0°C. However, the activator deficient activity may increase up to 200%. If stored at 4°C, both the activated and activator deficient activity, may decrease approx. 30% in 24 hrs. Warnings Crude preparation which has been stripped of the protein activator, calmodulin. Protein determined by Warburg-Christian unless specified otherwise. Function calcium-and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity; calmodulin-dependent cyclic-nucleotide phosphodiesterase activity; protein binding Synonyms cyclic 3',5'-mononucleotide phosphodiesterase; PDE; cyclic 3',5'-nucleotide phosphodiesterase; cyclic 3',5'-phosphodiesterase; 3',5'-nucleotide phosphodiesterase; 3':5'-cyclic nucleotide 5'-nucleotidohydrolase; 3',5'-cyclonucleotide phosphodiesterase; cyclic nucleotide phosphodiesterase; 3', 5'-cyclic nucleoside monophosphate phosphodiesterase; 3':5'-monophosphate phosphodiesterase (cyclic CMP); cytidine 3':5'-monophosphate phosphodiesterase (cyclic CMP); cyclic 3',5-nucleotide monophosphate phosphodiesterase; nucleoside 3',5'-cyclic phosphate diesterase; nucleoside-3',5-monophosphate phosphodiesterase; EC 3.1.4.17 category Specialty Chemicals(c26) cas_num 9040-59-9 Basic Info-
Product Name:
3′,5′-Cyclic nucleotide phosphodiesterase
Other Name:3′,5′-Cyclic nucleotide phosphodiesterase;Phosphodiesterase,cyclic 3′,5′-nucleotide;Cyclic 3′,5′-phosphodiesterase;3′,5′-Nucleotide phosphodiesterase;3′,5′-Cyclic nucleoside monophosphate phosphodiesterase;Cyclic 3′,5′-nucleotide phosphodiesterase;Cyclic 3′,5′-nucleotide monophosphate phosphodiesterase;Cyclic nucleotide phosphodiesterase;Nucleoside-3′,5′-monophosphate phosphodiesterase;E.C. 3.1.4.17;EC 3.1.4.17;3′,5′-Cyclonucleotide phosphodiesterase;Cyclic 3′,5′-mononucleotide phosphodiesterase;Cyclic nucleotide phosphohydrolase;Multifunctional phosphodiesterase;CNPase;3′,5′-Cyclonucleotide phosphodiesterases;3′,5′-Cyclic nucleotide phosphodiesterases;Nucleoside-3′,5′-monophosphate phosphodiesterases;3′,5′-Cyclic nucleoside monophosphate phosphodiesterases;Cyclic 3′,5′-nucleotide phosphodiesterases;Cyclic 3′,5′-nucleotide monophosphate phosphodiesterases;Cyclic 3′,5′-mononucleotide phosphodiesterases;3′,5′-Nucleotide phosphodiesterases;Multifunctional phosphodiesterases;Cyclic 3′,5′-phosphodiesterases;9068-51-3
CAS No.:9040-59-9
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Hazard IdentificationClassification of the substance or mixture
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no data available
Handling and StoragePrecautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.
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Seller Information
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Business Type:
Manufactory
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Main Products:
Coenzymes,Inhibito,Enzymes,Zymogens,Substrates,Native Microorganism Creatine Amidinohydrolase
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Location:
Shirley, New York 11967, USA
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Payment Terms:
TT against copy of documents,D/P
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Average lead Time:
15
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Total Annual Revenue:
$1 million-$2.5 million
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Year of Establishment:
2004
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