Native Wheat germ Topoisomerase I
1 Inquiries
80449-01-0
2026-07-12
Coenzymes,Inhibito,Enzymes,Zymogens,Substrates,Native Microorganism Creatine Amidinohydrolase
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Product Description
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Seller Information
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Inquiry History
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Description
ProductName Native Wheat germ Topoisomerase I Cat No NATE-0709 Description Topoisomerase I relaxes supercoiled DNA molecules. The enzyme initiates transient breakages and rejoins of phosphodiester bonds in superhelical turns of closed-circular DNA. Enzyme activity is independent of right-and left-handed superhelices. Abbr TOPO I, Native (Wheat germ) Alias TOPO I; ω-protein Source Wheat germ Applications Suitable for: • Analsis of degree of DNA supercoiling • Forming knots and circles in single stranded DNA • Converting complementary single stranded DNA to double stranded, circular forms • Rejoining nicks in double-stranded DNA Product Overview Topoisomerase I relaxes supercoiled DNA molecules. The enzyme initiates transient breakages and rejoins of phosphodiester bonds in superhelical turns of closedcircular dsDNA. Form buffered aqueous glycerol solution Enzyme Commission Number EC 5.99.1.2 CAS No 80449-01-0 Molecular Weight mol wt 97 kDa Unit Definition One unit will convert 1μg of supercoiled pGEM9Zf (−) plasmid DNA to the relaxed form in 30 min at 37°C. Storage −70°C Warnings To preserve enzyme activity, avoid multiple freeze-thaw cycles and frequent temperature variations. Synonyms Topoisomerase I; EC 5.99.1.2; type I DNA topoisomerase; untwisting enzyme; relaxing enzyme; nicking-closing enzyme; swivelase; ω-protein; deoxyribonucleate topoisomerase; topoisomerase; type I DNA topoisomerase; DNA topoisomerase; TOPO I category Specialty Chemicals(c26) cas_num 80449-01-0 Basic Info-
Product Name:
TOPOISOMERASEI
Other Name:TOPO I;TOPOISOMERASE I;DNA TOPOISOMERASE I;dna relaxing enzyme;Topoisomerase I, hl-60 cell;Topoisomerase I, L1210 cell;Topoisomerase I, calf thymus;topoisomerase I from wheat germ;Dna topoisomerase I, calf thymus;Dna topoisomerase ii, calf thymus
CAS No.:80449-01-0
Molecular Formula:C20H27N3O
InChIKeys:OVFMPNAYXDYMBS-BCZMGUNLSA-N
Molecular Weight:325.44788
Exact Mass:325.215
Categories:
Characteristics-
PSA:
58.4
XLogP3:2.8
Hazard IdentificationClassification of the substance or mixture
no data available
GHS label elements, including precautionary statements
Pictogram(s) no data available Signal word no data available
Hazard statement(s) no data available
Precautionary statement(s) Prevention no data available
Response no data available
Storage no data available
Disposal no data available
Other hazards which do not result in classification
no data available
Handling and StoragePrecautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.
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Seller Information
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Business Type:
Manufactory
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Main Products:
Coenzymes,Inhibito,Enzymes,Zymogens,Substrates,Native Microorganism Creatine Amidinohydrolase
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Location:
Shirley, New York 11967, USA
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Payment Terms:
TT against copy of documents,D/P
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Average lead Time:
15
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Total Annual Revenue:
$1 million-$2.5 million
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Year of Establishment:
2004
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Inquiry History1 Inquiries
Country Product Purchase Quantity Date Posted 
India
Native Wheat germ Topoisomerase I
500 Apr 28, 2026 Post an enquiry for this product