TG100-115
677297-51-7
99%
2026-08-12
Coenzymes,Inhibito,Enzymes,Zymogens,Substrates,Native Microorganism Creatine Amidinohydrolase
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Product Description
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Seller Information
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Description
ProductName TG100-115 Cat No CEI-0130 Description TG100-115 can inhibit PI3K-gamma and PI3K-delta with IC50 of 83 nM and 235 nM. CAS No 677297-51-7 Molecular Weight 346.34 Purity >99% Storage 2 years at -20centigrade Powder Targets PI3K-gamma, PI3K-delta Molecular Formula C18H14N6O2 Chemical Name 6,7-Bis(3-hydroxyphenyl)pteridine-2,4-diamine Solubility DMSO 9 mg/mL Water In vitro TG100-115 can inihbit PI3K-gamma and PI3K-delta with IC50 of 83 nM and 235 nM. TG100-115 has no effects on EC proliferation even at relatively high concentrations (up to 10 uM). In vivo TG100-115 can block histamine-induced permeability. In a rodent hindpaw model, TG100-115 strongly antagonized both the edema and leukocyte Infiltration. Blockade was seen with TG100-115 doses as low as 0.5 mg/kg and persisted over a period of several hours. But TG100-115 does not block VEGF-induced angiogenesis in vivo. category Inhibitors(c1514) cas_num 677297-51-7 Basic Info-
Product Name:
3,3'-(2,4-Diamino-6,7-pteridinediyl)bisphenol
Other Name:3,3'-(2,4-Diamino-6,7-pteridinediyl)bisphenol;6,7-Bis(3-hydroxyphenyl)pteridine-2,4-diamine;3,3'-(2,4-Diamino-6,7-pteridinediyl)bisphenol TG100-115;TG100-115, >=98%;3,3,-(2,4-diaminopteridine-6,7-diyl)diphenol
CAS No.:677297-51-7
Molecular Formula:C18H14N6O2
InChIKeys:UJIAQDJKSXQLIT-UHFFFAOYSA-N
Molecular Weight:346.3
Exact Mass:346.117828
UNII:7ACH1U1E2M
DSSTox ID:DTXSID20218009
Categories:
Characteristics-
PSA:
144
XLogP3:1.7
Density:1.5±0.1 g/cm3
Flash Point:376.9±34.3 °C
Refractive Index:1.803
Hazard IdentificationClassification of the substance or mixture
no data available
GHS label elements, including precautionary statements
Pictogram(s) no data available Signal word no data available
Hazard statement(s) no data available
Precautionary statement(s) Prevention no data available
Response no data available
Storage no data available
Disposal no data available
Other hazards which do not result in classification
no data available
Handling and StoragePrecautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.
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Seller Information
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Business Type:
Manufactory
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Main Products:
Coenzymes,Inhibito,Enzymes,Zymogens,Substrates,Native Microorganism Creatine Amidinohydrolase
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Location:
Shirley, New York 11967, USA
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Payment Terms:
TT against copy of documents,D/P
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Average lead Time:
15
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Total Annual Revenue:
$1 million-$2.5 million
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Year of Establishment:
2004
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