Tie2 kinase inhibitor
948557-43-5
99%
2026-07-05
Coenzymes,Inhibito,Enzymes,Zymogens,Substrates,Native Microorganism Creatine Amidinohydrolase
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Product Description
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Seller Information
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Description
ProductName Tie2 kinase inhibitor Cat No CEI-0025 Description Tie2 kinase inhibitor CAS No 948557-43-5 Molecular Weight 439.53 Purity >99% Storage 2 years at -20centigrade Powder Targets Tie2 kinase Molecular Formula C26H21N3O2S Chemical Name 4-(5-(6-methoxynaphthalen-2-yl)-2-(4-(methylsulfinyl)phenyl)-1H-imidazol-4-yl)pyridine Solubility DMSO 35 mg/mL， Water In vitro Tie2 kinase inhibitor exhibits a moderate inhibitory activity against Tie2 tyrosine kinase. Tie2 kinase inhibitor also shows moderate cellular activities with IC50 of 232 nM in HEL cells. Furthermore, Tie2 kinase inhibitor has a remarkable selectivity for Tie2 over p38 (IC50=50 uM) and a >10-fold selectivity over VEGFR2, VEGFR3, and PDGFR1beta. category Inhibitors(c1514) cas_num 948557-43-5 Basic Info-
Product Name:
Tie2 kinase inhibitor
Other Name:4-(6-Methoxy-2-naphthyl)-2-(4-methylsulfinylphenyl)-5-(4-pyridyl)-1H-imidazole;Tie2 kinase inhibitor;4-[4-(6-Methoxy-2-naphthalenyl)-2-[4-(Methylsulfinyl)phenyl]-1H-iMidazol-5-yl]pyridine;4-(5-(6-methoxynaphthalen-2-yl)-2-(4-(methylsulfinyl)phenyl)-1H-imidazol-4-yl)pyridine
CAS No.:948557-43-5
Molecular Formula:C26H21N3O2S
InChIKeys:SINQIEAULQKUPD-UHFFFAOYSA-N
Molecular Weight:439.52884
Exact Mass:439.135437
Categories:
Characteristics-
PSA:
87.1
XLogP3:4.3
Density:1.4±0.1 g/cm3
Boiling Point:699.8±55.0°C at 760 mmHg
Flash Point:377.0±31.5 °C
Refractive Index:1.746
Hazard IdentificationClassification of the substance or mixture
no data available
GHS label elements, including precautionary statements
Pictogram(s) no data available Signal word no data available
Hazard statement(s) no data available
Precautionary statement(s) Prevention no data available
Response no data available
Storage no data available
Disposal no data available
Other hazards which do not result in classification
no data available
Handling and StoragePrecautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.
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Seller Information
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Business Type:
Manufactory
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Main Products:
Coenzymes,Inhibito,Enzymes,Zymogens,Substrates,Native Microorganism Creatine Amidinohydrolase
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Location:
Shirley, New York 11967, USA
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Payment Terms:
TT against copy of documents,D/P
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Average lead Time:
15
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Total Annual Revenue:
$1 million-$2.5 million
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Year of Establishment:
2004
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