Puromycin Dihydrochloride
58-58-2
98%
2026-07-12
Coenzymes,Inhibito,Enzymes,Zymogens,Substrates,Native Microorganism Creatine Amidinohydrolase
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Product Description
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Seller Information
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Description
ProductName Puromycin Dihydrochloride Cat No CEI-0634 Description A nucleoside antibiotic. It inhibits protein synthesis by disrupting peptide transfer on ribosomes causing premature chain termination during translation. It is a potent translational inhibitor in both prokaryotic and eukaryotic cells. Resistance to puromycin is conferred by the puromycin N-acetyl-transferase gene (pac) from Streptomyces. Puromycin has a fast mode of action, causing rapid cell death at low antibiotic concentrations. Adherent mammalian cells are sensitive to concentrations of 2 to 5 µg /ml, while cells in suspension are sensitive to concentrations as low as 0.5 to 2 µg /ml Appearance Liquid Product Overview A protein synthesis inhibitor CAS No 58-58-2 Molecular Weight 156.22 Purity >98% Storage -80 centigrade Targets Protein Synthesis Molecular Formula C₂₂H₂₉N₇O₅ · 2HCl Chemical Name 3′-[α-Amino-p-methoxyhydrocinnamamido]-3′-deoxy-N,N-dimethyladenosine dihydrochloride Shipping Conditions Dry Ice category Antibiotics(c1416) cas_num 58-58-2 Basic Info-
Product Name:
Puromycin hydrochloride
Other Name:Adenosine,3′-[[(2S)-2-amino-3-(4-methoxyphenyl)-1-oxopropyl]amino]-3′-deoxy-N,N-dimethyl-,hydrochloride (1:2);Adenosine,3′-(α-amino-p-methoxyhydrocinnamamido)-3′-deoxy-N,N-dimethyl-,dihydrochloride,L-;Adenosine,3′-[[2-amino-3-(4-methoxyphenyl)-1-oxopropyl]amino]-3′-deoxy-N,N-dimethyl-,dihydrochloride,(S)-;Adenosine,3′-[[(2S)-2-amino-3-(4-methoxyphenyl)-1-oxopropyl]amino]-3′-deoxy-N,N-dimethyl-,dihydrochloride;CL 16,536;3′-(L-α-Amino-p-methoxyhydrocinnamamido)-3′-deoxy-N,N-dimethyladenosine dihydrochloride;PDH;Puromycin dihydrochloride;Puromycin hydrochloride;Stylomycin dihydrochloride;CL 13900 dihydrochloride;P 638 dihydrochloride;CL 16536;NSC 3055
CAS No.:58-58-2
Molecular Formula:C22H29N7O5.2ClH
InChIKeys:InChIKey=MKSVFGKWZLUTTO-FZFAUISWSA-N
Molecular Weight:544.43
Exact Mass:471.223017
EC Number:200-387-8
UNII:4A6ZS6Q2CL
DSSTox ID:DTXSID8036788|DTXSID7045861
NCI Thesaurus Code:C787
HScode:29419090
Categories:
Characteristics-
PSA:
160.88000
XLogP3:0.93
Appearance:Puromycin dihydrochloride is a white powder. (NTP, 1992)
Density:1.5±0.1 g/cm3
Melting Point:168-170℃
Refractive Index:1.701
Water Solubility:H2O: soluble 50mg/mL (Sterilize stock solution by filtration using 0.22 μm filter then store in aliquots at20 °C.)
Storage Conditions:−20°C
Toxicity:LD50 oral in guinea pig: 600mg/kg
Air and Water Reactions:Water soluble.
Reactive Group:Alcohols and Polyols
Reactivity Profile:PUROMYCIN DIHYDROCHLORIDE is sensitive to prolonged exposure to heat. (NTP, 1992). Behaves as a very weak acid in solution.
Hazard IdentificationClassification of the substance or mixture
Acute toxicity - Category 4, Oral
GHS label elements, including precautionary statements
Pictogram(s) 
Signal word Warning
Hazard statement(s) H302 Harmful if swallowed
Precautionary statement(s) Prevention P264 Wash ... thoroughly after handling.
P270 Do not eat, drink or smoke when using this product.
Response P301+P317 IF SWALLOWED: Get medical help.
P330 Rinse mouth.
Storage none
Disposal P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.
Other hazards which do not result in classification
no data available
Handling and StoragePrecautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.
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Seller Information
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Business Type:
Manufactory
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Main Products:
Coenzymes,Inhibito,Enzymes,Zymogens,Substrates,Native Microorganism Creatine Amidinohydrolase
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Location:
Shirley, New York 11967, USA
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Payment Terms:
TT against copy of documents,D/P
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Average lead Time:
15
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Total Annual Revenue:
$1 million-$2.5 million
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Year of Establishment:
2004
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Country Product Purchase Quantity Date Posted Post an enquiry for this product