Aprepitant(MK-0869)
1 Inquiries
170729-80-3
99%
2026-06-30
Coenzymes,Inhibito,Enzymes,Zymogens,Substrates,Native Microorganism Creatine Amidinohydrolase
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Product Description
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Seller Information
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Inquiry History
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Description
ProductName Aprepitant(MK-0869) Cat No CEI-0371 Description The substance P receptor antagonist MK-0869 shows antidepressant and anxiolytic activity in depressed outpatients which was comparable to a standard SSRI. Alias MK-869, L-754030, Emend CAS No 170729-80-3 Molecular Weight 534.43 Purity >99% Storage 2 years -20centigrade Powder Synonyms MK-869, L-754030, Emend Targets CYP3A4 Molecular Formula C23H21F7N4O3 In vitro MK-869 is the substance P inhibitor. MK-869 showed antidepressant and anxiolytic activity. category Antiemetics(c1121) cas_num 170729-80-3 Basic Info-
Product Name:
Aprepitant
Other Name:3H-1,2,4-Triazol-3-one,5-[[(2R,3S)-2-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-4-morpholinyl]methyl]-1,2-dihydro-;3H-1,2,4-Triazol-3-one,5-[[2-[1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-4-morpholinyl]methyl]-1,2-dihydro-,[2R-[2α(R*),3α]]-;5-[[(2R,3S)-2-[(1R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-4-morpholinyl]methyl]-1,2-dihydro-3H-1,2,4-triazol-3-one;L 754030;MK 869;Aprepitant;MK 0869;Emend;ONO 7436;221350-96-5
CAS No.:170729-80-3
Molecular Formula:C23H21F7N4O3
InChIKeys:InChIKey=ATALOFNDEOCMKK-OITMNORJSA-N
Molecular Weight:534.4266624
Exact Mass:534.43
EC Number:1806241-263-5
UNII:1NF15YR6UY
NSC Number:748825
DSSTox ID:DTXSID3049047
NCI Thesaurus Code:C49173
ATC Code:A04AD12|A - Alimentary tract and metabolism
HScode:2934990002
Categories:
Characteristics-
PSA:
75.2
XLogP3:4.2
Appearance:Solid
Density:1.51±0.1 g/cm3(Predicted)
Melting Point:255 °C
Refractive Index:1.564
Water Solubility:Practically insoluble in water
Storage Conditions:-20°C Freezer
Specific rotation:D25 +69° (c = 1.00 in methanol)
Hazard IdentificationClassification of the substance or mixture
Specific target organ toxicity â repeated exposure, Category 2
Hazardous to the aquatic environment, long-term (Chronic) - Category Chronic 1
GHS label elements, including precautionary statements
Pictogram(s) 
Signal word Warning
Hazard statement(s) H373 May cause damage to organs through prolonged or repeated exposure
H410 Very toxic to aquatic life with long lasting effects
Precautionary statement(s) Prevention P260 Do not breathe dust/fume/gas/mist/vapours/spray.
P273 Avoid release to the environment.
Response P319 Get medical help if you feel unwell.
P391 Collect spillage.
Storage none
Disposal P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.
Other hazards which do not result in classification
no data available
Handling and StoragePrecautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.
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Seller Information
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Business Type:
Manufactory
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Main Products:
Coenzymes,Inhibito,Enzymes,Zymogens,Substrates,Native Microorganism Creatine Amidinohydrolase
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Location:
Shirley, New York 11967, USA
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Payment Terms:
TT against copy of documents,D/P
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Average lead Time:
15
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Total Annual Revenue:
$1 million-$2.5 million
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Year of Establishment:
2004
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Inquiry History1 Inquiries
Country Product Purchase Quantity Date Posted 
Pakistan
Aprepitant USP
2.00 KG Oct 15, 2025 Post an enquiry for this product