4-Methylumbelliferone
2 Inquiries
90-33-5
99%
2026-09-01
Coenzymes,Inhibito,Enzymes,Zymogens,Substrates,Native Microorganism Creatine Amidinohydrolase
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Product Description
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Seller Information
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Inquiry History
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Description
ProductName 4-Methylumbelliferone Cat No CEI-0375 Description 4-Methylumbelliferone Alias 4-MU CAS No 90-33-5 Molecular Weight 176.17 Purity >99% Storage 2 years at -20 centigrade Synonyms 4-MU Targets HA synthesis Molecular Formula C10H8O3 Chemical Name 1-cyclopropyl-6-fluoro-8-methoxy-7-(3-methylpiperazin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid Solubility DMSO 35 mg/mL, Water In vitro 4-Methylumbelliferone(4-MU) is a hyaluronic acid (HA) synthesis inhibitor with an IC50 of 0.4 mM. 4-MU inhibited proliferation, motility, and invasion of DU145, PC3-ML, LNCaP, C4-2B, and/or LAPC-4 cells. At IC(50) for HA synthesis (0.4 mM), 4-MU induced >3-fold apoptosis in prostate cancer cells, which could be prevented by the addition of HA. The anticancer effects of 4-MU, an orally bioavailable and relatively nontoxic agent, are primarily mediated by inhibition of HA signaling. category Digestive System Drugs(c1425) cas_num 90-33-5 Basic Info-
Product Name:
4-Methylumbelliferone
Other Name:2H-1-Benzopyran-2-one,7-hydroxy-4-methyl-;Coumarin,7-hydroxy-4-methyl-;Umbelliferone,4-methyl-;7-Hydroxy-4-methyl-2H-1-benzopyran-2-one;7-Hydroxy-4-methylcoumarin;Hymecromone;LM 94;4-Methyl-7-hydroxycoumarin;β-Methylumbelliferone;4-Methylumbelliferone;7-Hydroxy-4-methyl-2-oxo-3-chromene;Imecromone;Cantabiline;Bilcolic;Bilicante;Cantabilin;Eurogale;Medilla;Omega 127;Mendiaxon;Pilot 447;Coumarin 4;Cholestil;4-MU;Coumarin 456;7-Hydroxy-4-methyl-2-chromenone;Cholonerton;Cholspasmin;Himecol;Cumarote C;Biliton H;NSC 19026;NSC 9408;7-Hydroxy-4-methyl-2H-chromen-2-one;7-Hydroxy-4-methyl-2H-chomen-2-one;7-Hydroxyl-4-methylcoumarine;7-Hydroxy-4-methylbenzopyran-2-one;Odeston;7-Hydroxy-4-methyl-2H-chromen-2-on;56275-29-7
CAS No.:90-33-5
Molecular Formula:C10H8O3
InChIKeys:InChIKey=HSHNITRMYYLLCV-UHFFFAOYSA-N
Molecular Weight:176.17
Exact Mass:176.17
BRN:142217
EC Number:201-986-7
UNII:3T5NG4Q468
NSC Number:760397|19026|9408
DSSTox ID:DTXSID8025670
ATC Code:A - Alimentary tract and metabolism
HScode:29329990
Categories:
Characteristics-
PSA:
46.5
XLogP3:1.9
Appearance:off-white to yellow Crystalline Powder
Density:1.319 g/cm3
Melting Point:195.5 °C
Boiling Point:377.4ºC at 760 mmHg
Flash Point:174.5ºC
Water Solubility:Solubility Practically insoluble in water; slightly soluble in ethanol, ether,chloroform; soluble inmethanol
Storage Conditions:-20°C Freezer
Toxicity:LD50 oral in rat: 3850mg/kg
Air and Water Reactions:Insoluble in water.
Reactive Group:Esters, Sulfate Esters, Phosphate Esters, Thiophosphate Esters, and Borate Esters
Hazard IdentificationClassification of the substance or mixture
Skin irritation, Category 2
Eye irritation, Category 2
Specific target organ toxicity â single exposure, Category 3
GHS label elements, including precautionary statements
Pictogram(s) 
Signal word Warning
Hazard statement(s) H315 Causes skin irritation
H319 Causes serious eye irritation
H335 May cause respiratory irritation
Precautionary statement(s) Prevention P264 Wash ... thoroughly after handling.
P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P271 Use only outdoors or in a well-ventilated area.
Response P302+P352 IF ON SKIN: Wash with plenty of water/...
P321 Specific treatment (see ... on this label).
P332+P317 If skin irritation occurs: Get medical help.
P362+P364 Take off contaminated clothing and wash it before reuse.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing.
P319 Get medical help if you feel unwell.
Storage P403+P233 Store in a well-ventilated place. Keep container tightly closed.
P405 Store locked up.
Disposal P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.
Other hazards which do not result in classification
no data available
Handling and StoragePrecautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.
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Seller Information
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Business Type:
Manufactory
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Main Products:
Coenzymes,Inhibito,Enzymes,Zymogens,Substrates,Native Microorganism Creatine Amidinohydrolase
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Location:
Shirley, New York 11967, USA
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Payment Terms:
TT against copy of documents,D/P
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Average lead Time:
15
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Total Annual Revenue:
$1 million-$2.5 million
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Year of Establishment:
2004
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Inquiry History2 Inquiries
Country Product Purchase Quantity Date Posted 
Russia
4-Methylumbelliferone
1 MT Feb 8, 2025 
United States
7-hydroxy-4-methyl-3,4-dihydrochromen-2-one
1 KG Jul 14, 2026 Post an enquiry for this product
