Irinotecan Hydrochloride
100286-90-6
90%
2026-08-14
Coenzymes,Inhibito,Enzymes,Zymogens,Substrates,Native Microorganism Creatine Amidinohydrolase
-
Product Description
-
Seller Information
-
Description
ProductName Irinotecan Hydrochloride Cat No CEI-0467 Description An anticancer agent. This is a prodrug that is converted by tissue carboxylesterase to 7-ethyl-10-hydroxycamptothecin (SN-38), a potent inhibitor of DNA topoisomerase I. Appearance Off-white solid Product Overview A DNA topoisomerase I inhibitor CAS No 100286-90-6 Molecular Weight 799.77 Purity >90% by HPLC Storage -20 centigrade Targets TOP1MT Molecular Formula C₃₃H₃₈N₄O₆. HCl Chemical Name S)-4,11-diethyl-3,4,12,14-tetrahydro-4-hydroxy-3,14-dioxo1H-pyrano[3’,4’:6,7]-indolizino[1,2-b]quinolin-9-yl-[1,4’bipiperidine]-1’-carboxylate, Hydrochloride Solubility DMSO Shipping Conditions Gel pack category Plant Extracts(c1524) cas_num 100286-90-6 Basic Info-
Product Name:
Irinotecan hydrochloride
Other Name:[1,4′-Bipiperidine]-1′-carboxylic acid,(4S)-4,11-diethyl-3,4,12,14-tetrahydro-4-hydroxy-3,14-dioxo-1H-pyrano[3′,4′:6,7]indolizino[1,2-b]quinolin-9-yl ester,hydrochloride (1:1);[1,4′-Bipiperidine]-1′-carboxylic acid,4,11-diethyl-3,4,12,14-tetrahydro-4-hydroxy-3,14-dioxo-1H-pyrano[3′,4′:6,7]indolizino[1,2-b]quinolin-9-yl ester,monohydrochloride,(S)-;[1,4′-Bipiperidine]-1′-carboxylic acid,(4S)-4,11-diethyl-3,4,12,14-tetrahydro-4-hydroxy-3,14-dioxo-1H-pyrano[3′,4′:6,7]indolizino[1,2-b]quinolin-9-yl ester,monohydrochloride;1H-Pyrano[3′,4′:6,7]indolizino[1,2-b]quinoline,[1,4′-bipiperidine]-1′-carboxylic acid deriv.;CPT 11;Camptothecin 11;7-Ethyl-10-[[4-(1-piperidyl)-1-piperidyl]carbonyloxy]camptothecin hydrochloride;Camptothecin 11 hydrochloride;Irinotecan hydrochloride;U 101440E;Topotecin;Campto;Camptosar;Topotesin;(19S)-10,19-Diethyl-19-hydroxy-14,18-dioxo-17-oxa-3,13-diazapentacyclo[11.8.0.0[2,11].0[4,9].0[15,20]]henicosa-1(21),2(11),3,5,7,9,15(20)-heptaen-7-yl 4-(piperidin-1-yl)piperidine-1-carboxylate hydrochloride;111348-33-5
CAS No.:100286-90-6
Molecular Formula:C33H38N4O6.ClH
InChIKeys:InChIKey=GURKHSYORGJETM-WAQYZQTGSA-N
Molecular Weight:623.14
Exact Mass:622.255798
EC Number:1308068-626-2
UNII:06X131E4OE
NSC Number:759878|616348
DSSTox ID:DTXSID6045953
HScode:29399990
Categories:
Characteristics-
PSA:
113
XLogP3:4.76890
Appearance:Yellow crystalline powder
Melting Point:250-256°C (dec.)
Boiling Point:257 °C
Flash Point:482ºC
Refractive Index:67.7 ° (C=1, H2O)
Water Solubility:soluble in DMSO at 100mg/ml. soluble in water at 25mg/ml with warming;soluble in DMF at approximately 20mg/ml. Sparingly soluble in aqueous buffers.
Storage Conditions:Refrigerator
Vapor Pressure:1.31E-32mmHg at 25°C
Hazard IdentificationClassification of the substance or mixture
Acute toxicity - Category 4, Oral
GHS label elements, including precautionary statements
Pictogram(s) 
Signal word Warning
Hazard statement(s) H302 Harmful if swallowed
Precautionary statement(s) Prevention P264 Wash ... thoroughly after handling.
P270 Do not eat, drink or smoke when using this product.
Response P301+P317 IF SWALLOWED: Get medical help.
P330 Rinse mouth.
Storage none
Disposal P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.
Other hazards which do not result in classification
no data available
Handling and StoragePrecautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.
-
-
Seller Information
-
Business Type:
Manufactory
-
Main Products:
Coenzymes,Inhibito,Enzymes,Zymogens,Substrates,Native Microorganism Creatine Amidinohydrolase
-
Location:
Shirley, New York 11967, USA
-
Payment Terms:
TT against copy of documents,D/P
-
Average lead Time:
15
-
Total Annual Revenue:
$1 million-$2.5 million
-
Year of Establishment:
2004
-
-
Country Product Purchase Quantity Date Posted Post an enquiry for this product