CGP60474
164658-13-3
0.98%
2026-09-24
Coenzymes,Inhibito,Enzymes,Zymogens,Substrates,Native Microorganism Creatine Amidinohydrolase
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Product Description
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Seller Information
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Description
ProductName CGP60474 Cat No CEI-1276 Product Overview CGP60474 is a potent inhibitor of cyclin-dependent kinases (CDKs) with IC50 value of 17 nM for CDK1.It is also an inhibitor of Protein Kinase C (PKC). CDKs are a family of protein kinases regulating the cell cycle. PKC plays an important role in signal transductions, cellular proliferation and differentiation. CGP60474 was highly selective for PKC than other serine/threonine and tyrosine kinases and showed competitive kinetics relative to ATP. CAS No 164658-13-3 Molecular Weight 355.82 Purity 0.98 Storage Store at -20°C Synonyms CGP-60474; CGP 60474 Targets CDKs; PKC Molecular Formula C18H18ClN5O Chemical Name 3-[[4-[2-(3-chloroanilino)pyrimidin-4-yl]pyridin-2-yl]amino]propan-1-ol Solubility Soluble in DMSO Shipping Conditions Evaluation sample solution: ship with blue ice. All other available size: ship with RT, or blue ice upon request category Specialty Chemicals(c26) cas_num 164658-13-3 ECHEMI Editorial ReferenceCGP60474 is a potent VEGFR-2 inhibitor, with an IC50 of 84 nM, and also an ATP-competitive PKC inhibitor.
3-[[4-[2-(3-chloroanilino)-4-pyrimidinyl]-2-pyridinyl]amino]-1-propanol is a substituted aniline.Basic Info-
Product Name:
3-[[4-[2-[(3-Chlorophenyl)amino]-4-pyrimidinyl]-2-pyridinyl]amino]-1-propanol
Other Name:1-Propanol, 3-((4-(2-((3-chlorophenyl)amino)-4-pyrimidinyl)-2-pyridinyl)amino)-;3-((4-(2-((3-Chlorophenyl)amino)-4-pyrimidinyl)-2-pyridinyl)amino)-1-propanol;3-(4-(2-(3-chlorophenylamino)pyrimidin-4-yl)pyridin-2-ylamino)propanol;CGP 60474;CGP-60474;CGP60474;UNII-16IP6G5MLC;3-[[4-[2-[(3-Chlorophenyl)amino]-4-pyrimidinyl]-2-pyridinyl]amino]-1-propanol
CAS No.:164658-13-3
Molecular Formula:C18H18ClN5O
InChIKeys:IYNDTACKOAXKBJ-UHFFFAOYSA-N
Molecular Weight:355.82142
Exact Mass:355.12000
UNII:16IP6G5MLC
DSSTox ID:DTXSID00167788
Categories:
Characteristics-
PSA:
83
XLogP3:3.8
Density:1.356
Melting Point:144-147℃
Boiling Point:630.6±65.0 °C(Predicted)
Flash Point:335.2ºC
Refractive Index:1.685
Vapor Pressure:9.02E-17mmHg at 25°C
Hazard IdentificationClassification of the substance or mixture
no data available
GHS label elements, including precautionary statements
Pictogram(s) no data available Signal word no data available
Hazard statement(s) no data available
Precautionary statement(s) Prevention no data available
Response no data available
Storage no data available
Disposal no data available
Other hazards which do not result in classification
no data available
Handling and StoragePrecautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.
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Seller Information
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Business Type:
Manufactory
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Main Products:
Coenzymes,Inhibito,Enzymes,Zymogens,Substrates,Native Microorganism Creatine Amidinohydrolase
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Location:
Shirley, New York 11967, USA
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Payment Terms:
TT against copy of documents,D/P
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Average lead Time:
15
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Total Annual Revenue:
$1 million-$2.5 million
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Year of Establishment:
2004
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Country Product Purchase Quantity Date Posted Post an enquiry for this product