CPA inhibitor
223532-02-3
0.98%
2026-08-20
Coenzymes,Inhibito,Enzymes,Zymogens,Substrates,Native Microorganism Creatine Amidinohydrolase
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Product Description
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Seller Information
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Description
ProductName CPA inhibitor Cat No CEI-1294 Description CPA inhibitor is a potent inhibitor for carboxypeptidase A (CPA) Product Overview CPA inhibitor (carboxypeptidase inhibitor) is a potent inhibitor of EGFR. EGFR (epidermal growth factor receptor) is a member of ErbB family of receptors and binds to the members of EGF-family. It has been reported that EGFR aberrant expression is correlated with cancer, inflammatory disease, monogenic disease and so on. When tested with human pancreatic adenocarcinoma cell lines Capan-1, CPA inhibitor treatment significantly inhibited cells growth at the concentration more than 10 μg/ml and pre-treatment markedly inhibited cell proliferation rate. In A431 and MDA-MB-453 cell lines, pre-treated with CPA inhibitor markedly suppressed EGFR expression level. In nude mouse model with Capan-1 cells subcutaneous xenograft, administration of CPA inhibitor significantly reduced solid tumor growth without side effect. CAS No 223532-02-3 Molecular Weight 313.36 Purity 0.98 Storage Store at -20°C Synonyms carboxypeptidase inhibitor Targets CPA Molecular Formula C18H19NO4 Chemical Name 2-benzyl-3-[hydroxy-(2-phenylacetyl)amino]propanoic acid Solubility Soluble in DMSO Shipping Conditions Evaluation sample solution: ship with blue ice. All other available size: ship with RT, or blue ice upon request category Specialty Chemicals(c26) cas_num 223532-02-3 Basic Info-
Product Name:
alpha-[[Hydroxy(2-phenylacetyl)amino]methyl]benzenepropanoic acid
Other Name:CPA inhibitor;CHEMBL161702;carboxypeptidase inhibitor;DTXSID90658554;alpha-[[Hydroxy(2-phenylacetyl)aMino]Methyl]benzenepropanoic acid;BCP25346;3560AH;BDBM50075829;CS-0335;HY-70005
CAS No.:223532-02-3
Molecular Formula:C18H19NO4
InChIKeys:PONANXDRJJIGPG-UHFFFAOYSA-N
Molecular Weight:313.34776
Exact Mass:313.13100
DSSTox ID:DTXSID90658554
Categories:
Characteristics-
PSA:
77.8
XLogP3:2.39040
Density:1.274
Hazard IdentificationClassification of the substance or mixture
no data available
GHS label elements, including precautionary statements
Pictogram(s) no data available Signal word no data available
Hazard statement(s) no data available
Precautionary statement(s) Prevention no data available
Response no data available
Storage no data available
Disposal no data available
Other hazards which do not result in classification
no data available
Handling and StoragePrecautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.
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Seller Information
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Business Type:
Manufactory
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Main Products:
Coenzymes,Inhibito,Enzymes,Zymogens,Substrates,Native Microorganism Creatine Amidinohydrolase
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Location:
Shirley, New York 11967, USA
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Payment Terms:
TT against copy of documents,D/P
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Average lead Time:
15
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Total Annual Revenue:
$1 million-$2.5 million
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Year of Establishment:
2004
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