GW843682X
660868-91-7
0.98%
2026-08-29
Coenzymes,Inhibito,Enzymes,Zymogens,Substrates,Native Microorganism Creatine Amidinohydrolase
-
Product Description
-
Seller Information
-
Description
ProductName GW843682X Cat No CEI-1359 Product Overview GW843682X is a selective inhibitor of polo-like kinase 1 (PLK1) and polo-like kinase 3 (PLK3) (IC50 values are 2.2 and 9.1 nM respectively). GW843682X displays >100-fold selectivity over 30 other kinases tested including cdk1 and cdk2.GW843682X inhibits proliferation of most tumor cells in vitro and is selective over normal diploid fibroblasts. CAS No 660868-91-7 Molecular Weight 477.46 Purity 0.98 Storage Store at -20°C Synonyms GW 843682X; GW843682; GW-843682X Targets PLK1/PLK3 Molecular Formula C22H18F3N3O4S Chemical Name 5-(5,6-dimethoxybenzimidazol-1-yl)-3-[[2-(trifluoromethyl)phenyl]methoxy]thiophene-2-carboxamide Solubility Soluble in DMSO > 10 mM Shipping Conditions Evaluation sample solution: ship with blue ice. All other available size: ship with RT, or blue ice upon request category Specialty Chemicals(c26) cas_num 660868-91-7 Basic Info-
Product Name:
GW843682,5-(5,6-Dimethoxy-1H-benzimidazol-1-yl)-3-{[2-(trifluoromethyl)-benzyl]oxy}thiophene-2-carboxamide
Other Name:GW843682, 5-(5,6-Dimethoxy-1H-benzimidazol-1-yl)-3-{[2-(trifluoromethyl)-benzyl]oxy}thiophene-2-carboxamide;GW843682X;3-(2-(Trifluoromethyl)benzyloxy)-5-(5,6-dimethoxy-1H-benzo[d]imidazol-1-yl)thiophene-2-carboxamide;Polo-like Kinase Inhibitor III;5-(5,6-Dimethoxy-1H-benzimidazol-1-yl)-3-{[2-(trifluoromethyl)-benzyl]oxy}thiophene-2-carboxamide;5-(5,6-Dimethoxy-1H-benzimidazol-1-yl)-3-[[2-(trifluoromethyl)phenyl]methoxy]-2-thiophenecarboxamide;GW843682;5-(5,6-dimethoxy-1H-benzo[d]imidazol-1-yl)-3-((2-(trifluoromethyl)benzyl)oxy)thiophene-2-carboxamide
CAS No.:660868-91-7
Molecular Formula:C22H18F3N3O4S
InChIKeys:JSKUWFIZUALZLX-UHFFFAOYSA-N
Molecular Weight:477.46
Exact Mass:477.09701172
EC Number:200-258-5
DSSTox ID:DTXSID80431373
Categories:
Characteristics-
PSA:
116.84000
XLogP3:5.50120
Density:1.45±0.1 g/cm3
Boiling Point:609.1±65.0 °C(Predicted)
Flash Point:322.183ºC
Storage Conditions:2-8ºC
PKA:15.03±0.50
-
-
Seller Information
-
Business Type:
Manufactory
-
Main Products:
Coenzymes,Inhibito,Enzymes,Zymogens,Substrates,Native Microorganism Creatine Amidinohydrolase
-
Location:
Shirley, New York 11967, USA
-
Payment Terms:
TT against copy of documents,D/P
-
Average lead Time:
15
-
Total Annual Revenue:
$1 million-$2.5 million
-
Year of Establishment:
2004
-
-
Country Product Purchase Quantity Date Posted Post an enquiry for this product