Rocaglamide
84573-16-0
98%
2026-09-17
Coenzymes,Inhibito,Enzymes,Zymogens,Substrates,Native Microorganism Creatine Amidinohydrolase
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Product Description
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Seller Information
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Description
ProductName Rocaglamide Cat No CEI-0589 Description An immunosuppressant and a potent inhibitor of NF-κB activation in T cells, with an almost complete inhibition at 200 nM. Suppresses cytokine production (IFN-γ, TNF-α, IL-2 and IL-4) and inhibits NF-AT in peripheral blood T cells at concentrations that do not impair NF-κB and AP-1 activities. Also induces mitochondria-mediated apoptosis in leukemia cells and sensitizes CD95/CD95L-mediated apoptosis in malignant T-cells by differential regulation of CD95L and c-FLIP expression. Alias Rocaglamide A Appearance White solid Product Overview An immunosuppressant CAS No 84573-16-0 Molecular Weight 228.2 Purity >98% by HPLC Storage -20 centigrade Synonyms Rocaglamide A Targets NFKB1 Molecular Formula C₂₉H₃₁NO₇ Solubility DMSO (100 mM) or H2O (100 mM) Shipping Conditions Gel pack category Alkaloids(c2322) cas_num 84573-16-0 ECHEMI Editorial ReferenceRocaglamide is a potent NF-κB activation inhibitor.Basic Info-
Product Name:
(1R,2R,3S,3aR,8bS)-2,3,3a,8b-Tetrahydro-1,8b-dihydroxy-6,8-dimethoxy-3a-(4-methoxyphenyl)-N,N-dimethyl-3-phenyl-1H-cyclopenta[b]benzofuran-2-carboxamide
Other Name:1H-Cyclopenta[b]benzofuran-2-carboxamide,2,3,3a,8b-tetrahydro-1,8b-dihydroxy-6,8-dimethoxy-3a-(4-methoxyphenyl)-N,N-dimethyl-3-phenyl-,(1R,2R,3S,3aR,8bS)-;1H-Cyclopenta[b]benzofuran-2-carboxamide,2,3,3a,8b-tetrahydro-1,8b-dihydroxy-6,8-dimethoxy-3a-(4-methoxyphenyl)-N,N-dimethyl-3-phenyl-,[1R-(1α,2α,3β,3aβ,8bβ)]-;(1R,2R,3S,3aR,8bS)-2,3,3a,8b-Tetrahydro-1,8b-dihydroxy-6,8-dimethoxy-3a-(4-methoxyphenyl)-N,N-dimethyl-3-phenyl-1H-cyclopenta[b]benzofuran-2-carboxamide;Rocaglamide;NSC 326408;Roc-A;Rocaglamide A;(-)-Rocaglamide
CAS No.:84573-16-0
Molecular Formula:C29H31NO7
InChIKeys:InChIKey=DAPAQENNNINUPW-IDAMAFBJSA-N
Molecular Weight:505.55894
Exact Mass:505.56
UNII:FRG4N852F7
NSC Number:326408
Categories:
Characteristics-
PSA:
97.7
XLogP3:3.10
Appearance:colorless
Density:1.3±0.1 g/cm3
Melting Point:117-118 °C
Boiling Point:667.3±55.0 °C at 760 mmHg
Flash Point:357.4±31.5 °C
Refractive Index:1.634
Storage Conditions:-20°C
Hazard IdentificationClassification of the substance or mixture
no data available
GHS label elements, including precautionary statements
Pictogram(s) no data available Signal word no data available
Hazard statement(s) no data available
Precautionary statement(s) Prevention no data available
Response no data available
Storage no data available
Disposal no data available
Other hazards which do not result in classification
no data available
Handling and StoragePrecautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.
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Seller Information
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Business Type:
Manufactory
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Main Products:
Coenzymes,Inhibito,Enzymes,Zymogens,Substrates,Native Microorganism Creatine Amidinohydrolase
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Location:
Shirley, New York 11967, USA
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Payment Terms:
TT against copy of documents,D/P
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Average lead Time:
15
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Total Annual Revenue:
$1 million-$2.5 million
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Year of Establishment:
2004
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Country Product Purchase Quantity Date Posted Post an enquiry for this product
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