GW-441756
504433-23-2
98%
2026-07-14
Coenzymes,Inhibito,Enzymes,Zymogens,Substrates,Native Microorganism Creatine Amidinohydrolase
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Product Description
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Seller Information
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Description
ProductName GW-441756 Cat No CEI-0964 Description Potent, selective inhibitor of the NGF receptor tyrosine kinase A (TrkA) (IC50 = 2 nM). Displays >100-fold selectivity over a range of other kinases. Blocks TrkA-mediated gammaH2AX production and apoptosis in TrkA-overexpressing cells. Cell permeable. Abbr GW-441756(NGFR) Alias 1, 3-Dihydro-3-[(1-methyl-1H-indol-3-yl)methylene]-2H-pyrrolo[3, 2-b]pyridin-2-one Appearance Orange powder Product Overview NGFR inhibitor CAS No 504433-23-2 Molecular Weight 275.1 Purity 98% (TLC: 5% CH3OH: CH2Cl2; Rf=0.4) mixture of E Synonyms 1,3-Dihydro-3-[(1-methyl-1H-indol-3-yl)methylene]-2H-pyrrolo[3,2-b]pyridin-2-one Targets NGFR Molecular Formula C17H13N3O Solubility May be dissolved in DMSO (25 mg/ml); or Ethanol (100 mg/ml) category Inhibitors(c1514) cas_num 504433-23-2 Basic Info-
Product Name:
GW441756
Other Name:1,3-DIHYDRO-3-[(1-METHYL-1H-INDOL-3-YL)METHYLENE]-2H-PYRROLO[3,2-B]PYRIDIN-2-ONE;GW 441756;Gw;2H-Pyrrolo[3,2-b]pyridin-2-one, 1,3-dihydro-3-[(1-methyl-1H-indol-3-yl)methylene]-;(Z)-3-((1-methyl-1H-indol-3-yl)methylene)-1H-pyrrolo[3,2-b]pyridin-2(3H)-one;-3-((1-methyl-1H-indol-3-yl)methylene)-1H-pyrrolo[3,2-b]pyridin-2(3H)-one;3-[(1-methylindol-3-yl)methylidene]-1H-pyrrolo[3,2-b]pyridin-2-one
CAS No.:504433-23-2
Molecular Formula:C17H13N3O
Molecular Weight:275.30462
Exact Mass:275.105865
Categories:
Characteristics-
Density:
1.3±0.1 g/cm3
Boiling Point:567.985°C at 760 mmHg
Flash Point:297.3±30.1 °C
Refractive Index:1.708
Storage Conditions:Store at RT
Hazard IdentificationClassification of the substance or mixture
no data available
GHS label elements, including precautionary statements
Pictogram(s) no data available Signal word no data available
Hazard statement(s) no data available
Precautionary statement(s) Prevention no data available
Response no data available
Storage no data available
Disposal no data available
Other hazards which do not result in classification
no data available
Handling and StoragePrecautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.
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Seller Information
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Business Type:
Manufactory
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Main Products:
Coenzymes,Inhibito,Enzymes,Zymogens,Substrates,Native Microorganism Creatine Amidinohydrolase
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Location:
Shirley, New York 11967, USA
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Payment Terms:
TT against copy of documents,D/P
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Average lead Time:
15
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Total Annual Revenue:
$1 million-$2.5 million
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Year of Establishment:
2004
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Country Product Purchase Quantity Date Posted Post an enquiry for this product