Bosutinib
380843-75-4
95%
2026-07-27
Coenzymes,Inhibito,Enzymes,Zymogens,Substrates,Native Microorganism Creatine Amidinohydrolase
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Product Description
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Seller Information
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Description
ProductName Bosutinib Cat No CEI-1091 Description Bosutinib (SKI-606) is a novel, dual Src/Abl inhibitor with IC50 of 1.2 nM and 1 nM, respectively. Abbr Bosutinib(SRC, ABL1) Alias RP5-823N20.1, ASV, SRC1, c-SRC, p60-Src Product Overview Src/Abl inhibitor CAS No 380843-75-4 Molecular Weight 530.45 Purity > 95% Storage 4 centigrade Synonyms RP5-823N20.1, ASV, SRC1, c-SRC, p60-Src Targets Src, Abl IC50 1.2 nM, 1 nM Molecular Formula C26H29Cl2N5O3 Chemical Name 4-((2,4-dichloro-5-methoxyphenyl)amino)-6-methoxy-7-(3-(4-methylpiperazin-1-yl)propoxy)quinoline-3-carbonitrile category Antineoplastic Agents(c1417) cas_num 380843-75-4 Basic Info-
Product Name:
Bosutinib
Other Name:3-Quinolinecarbonitrile,4-[(2,4-dichloro-5-methoxyphenyl)amino]-6-methoxy-7-[3-(4-methyl-1-piperazinyl)propoxy]-;4-[(2,4-Dichloro-5-methoxyphenyl)amino]-6-methoxy-7-[3-(4-methyl-1-piperazinyl)propoxy]-3-quinolinecarbonitrile;SKI 606;Bosutinib;SK 606;Bosulif;KIN 001-160
CAS No.:380843-75-4
Molecular Formula:C26H29Cl2N5O3
InChIKeys:InChIKey=UBPYILGKFZZVDX-UHFFFAOYSA-N
Molecular Weight:530.45
Exact Mass:530.45
EC Number:1308068-626-2
UNII:5018V4AEZ0
NCI Thesaurus Code:C60809
ATC Code:L01XE14|L - Antineoplastic and immunomodulating agents
HScode:29335990
Categories:
Characteristics-
PSA:
82.9
XLogP3:5.4
Appearance:off-white to light brown
Density:1.4±0.1 g/cm3
Melting Point:116-120 °C
Boiling Point:649.7±55.0°C at 760 mmHg
Flash Point:346.7±31.5 °C
Refractive Index:1.652
Water Solubility:DMSO: ≥15mg/mL
Storage Conditions:room temp
Hazard IdentificationClassification of the substance or mixture
Eye irritation, Category 2
Hazardous to the aquatic environment, long-term (Chronic) - Category Chronic 4
GHS label elements, including precautionary statements
Pictogram(s) 
Signal word Warning
Hazard statement(s) H319 Causes serious eye irritation
H413 May cause long lasting harmful effects to aquatic life
Precautionary statement(s) Prevention P264 Wash ... thoroughly after handling.
P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...
P273 Avoid release to the environment.
Response P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
Storage none
Disposal P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.
Other hazards which do not result in classification
no data available
Handling and StoragePrecautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.
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Seller Information
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Business Type:
Manufactory
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Main Products:
Coenzymes,Inhibito,Enzymes,Zymogens,Substrates,Native Microorganism Creatine Amidinohydrolase
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Location:
Shirley, New York 11967, USA
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Payment Terms:
TT against copy of documents,D/P
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Average lead Time:
15
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Total Annual Revenue:
$1 million-$2.5 million
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Year of Establishment:
2004
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Country Product Purchase Quantity Date Posted Post an enquiry for this product