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Home > Pharmaceutical Intermediates > Bulk Drug Intermediates > Bosutinib for Sale > Bosutinib CAS 380843-75-4 Dual Src/Abl Kinase Inhibitor for CML Research kr
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Bosutinib CAS 380843-75-4 Dual Src/Abl Kinase Inhibitor for CML Research kr

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Unit Price:

$100-130/G FOB

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CAS No.:

380843-75-4

Grade:

Reagent Grade

Content:

99%

Port:

qingdao

Brand:

//

Packaging:

10mg, 25mg, 50mg, 100mg, 1g

Price valid (until):

2026-08-09

Company Type:
Trader
Location:
China
Qualification:
Main Products:

3-(1-Naphthoyl)indole

  • Product Description

  • Seller Information

  • Description

    —— Product Specification ——

    Parameter Specification Details
    Product Name Bosutinib SKI-606, Bosulif
    CAS Number 380843-75-4 380843-75-4
    Molecular Formula C₂₆H₂₉Cl₂N₅O₃ 26 carbons, 29 hydrogens, 2 chlorine, 5 nitrogens, 3 oxygens
    Molecular Weight 530.45 g/mol
    Appearance Off-white to pale yellow powder Visual inspection
    Purity ≥98.0% Determined by HPLC
    Melting Point 116 – 120°C
    Density 1.36 g/cm³
    Solubility DMSO: ≥15 mg/mL; DMF: 20 mg/mL; Ethanol: 20 mg/mL
    pKa 7.63 ± 0.10 Predicted
    Storage Room temperature for short-term; -20°C for long-term Sealed containers, DMSO solutions stable 1 month at -20°C
    Packaging 10mg, 25mg, 50mg, 100mg, 500mg, 1g Amber glass vials
    Application Research use only Kinase inhibition studies, CML research, reference standard


    —— Product Detail ——

    Product Overview

    • Bosutinib (CAS 380843-75-4), also known as SKI-606 and marketed under the brand name Bosulif, is a synthetic quinolone derivative and potent dual kinase modulator that targets both Abl and Src kinases with potential antineoplastic activity . It appears as an off-white to pale yellow powder with the molecular formula C₂₆H₂₉Cl₂N₅O₃ and a molecular weight of 530.45 g/mol.

      With a purity of ≥98.0% by HPLC, Bosutinib is a well-established pharmaceutical compound approved by the FDA in September 2012 for the treatment of chronic myeloid leukemia (CML) in patients with resistance or intolerance to prior therapy


    Packaging & Shipping

    • Research quantities: 10mg, 25mg, 50mg amber glass vials

    • Bulk quantities: 100mg, 500mg, 1g amber glass bottles

    • Custom packaging available upon request

    • Not classified as hazardous material for transport under normal conditions

    • Product for research and analytical use only; not for human or veterinary use

    Shop CAS 18048-64-1 Eltrombopag Intermediate for Pharmaceutical Research  kr-Detailed Image 1

    Company profile ——


     Shop CAS 1231930-42-9 Abemaciclib Intermediate for Pharma researech use KR-Detailed Image 1

    Jinan Topfull Chemical Co., Ltd. is an international company rooted in China, specializing in the export of chemical products.

    Our company is committed to making every effort to provide ideal chemical products to potential customers worldwide, including but not limited to: organic/inorganic reagents, biological reagents, plant extracts, pharmaceutical intermediates, active pharmaceutical ingredients (APIs), reference standards, reference substances, peptides, and more. Meanwhile, we have established long-term and stable cooperative relationships with university laboratories and off-campus research institutions, enabling us to offer tailored product services based on customers' actual needs.

    We currently support customized services for most product categories, with supply quantities ranging from milligram (mg), gram (g) to kilogram (kg) levels, as well as wholesale. Product purity covers the full spectrum from 90% to 99.9%, providing customers with one-stop convenient services.

    To date, our products have been exported to developed countries such as the United States, Australia, Canada, Mexico, as well as EU member states including France, Germany, and many other countries and regions such as Nigeria, Ghana, Southeast Asia, and other parts of Asia. Our product quality and services have consistently received high praise.

    Looking ahead, our company will continue to serve as a bridge connecting China and the world, delivering high-quality products and services to global customers.

     

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    —— Q&A ——

    Q1: How to confirm the product quality before placing orders?
    A: By sending you available samples. Or if you have special requirements for the goods, we can prepare samples according to your requirements for confirmation.

    Q2: Can you supply free samples?
    A: Yes, we can provide a free sample, but the shipping cost will be paid by the customers. You can either pay the shipping cost or arrange a courier to collect the samples.

    Q3: How do you treat quality complaints?
    A: All our products are strictly tested by our QC and confirmed by QA; unqualified material will not be released to customers. If any quality problem is confirmed to be caused by us, we will replace the goods or refund your payment immediately.

    Q4: What is your MOQ? Is there a discount?
    A: For highvalue products, our MOQ starts from 1g and generally starts from 10g. For other lowprice products, our MOQ starts from 100g and 1kg.
    Q: Is there a discount?
    A: Yes, for larger quantities, we always support with better prices.

    Q5: How to start orders or make payments?
    A: You can send us your Purchase Order (if your company has one), or just send a simple confirmation by email or via Trade Manager. We will then send you a Proforma Invoice with our bank details for your confirmation, and you can make payment accordingly. If you have other preferred payment methods, we are open to discussion and negotiation.



    Certificates
    • Bosutinib CAS 380843-75-4 Dual Src/Abl Kinase Inhibitor for CML Research kr Certificates 1

    Basic Info
    Product Name:

    Bosutinib

    Other Name:

    3-Quinolinecarbonitrile,4-[(2,4-dichloro-5-methoxyphenyl)amino]-6-methoxy-7-[3-(4-methyl-1-piperazinyl)propoxy]-;4-[(2,4-Dichloro-5-methoxyphenyl)amino]-6-methoxy-7-[3-(4-methyl-1-piperazinyl)propoxy]-3-quinolinecarbonitrile;SKI 606;Bosutinib;SK 606;Bosulif;KIN 001-160

    CAS No.:

    380843-75-4

    Molecular Formula:

    C26H29Cl2N5O3

    InChIKeys:

    InChIKey=UBPYILGKFZZVDX-UHFFFAOYSA-N

    Molecular Weight:

    530.45

    Exact Mass:

    530.45

    EC Number:

    1308068-626-2

    UNII:

    5018V4AEZ0

    NCI Thesaurus Code:

    C60809

    ATC Code:

    L01XE14|L - Antineoplastic and immunomodulating agents

    HScode:

    29335990

    Characteristics
    PSA:

    82.9

    XLogP3:

    5.4

    Appearance:

    off-white to light brown

    Density:

    1.4±0.1 g/cm3

    Melting Point:

    116-120 °C

    Boiling Point:

    649.7±55.0°C at 760 mmHg

    Flash Point:

    346.7±31.5 °C

    Refractive Index:

    1.652

    Water Solubility:

    DMSO: ≥15mg/mL

    Storage Conditions:

    room temp

    Hazard Identification

    Classification of the substance or mixture

    Eye irritation, Category 2

    Hazardous to the aquatic environment, long-term (Chronic) - Category Chronic 4

    GHS label elements, including precautionary statements

    Pictogram(s)
    Signal word

    Warning

    Hazard statement(s)

    H319 Causes serious eye irritation

    H413 May cause long lasting harmful effects to aquatic life

    Precautionary statement(s)
    Prevention

    P264 Wash ... thoroughly after handling.

    P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...

    P273 Avoid release to the environment.

    Response

    P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

    Storage

    none

    Disposal

    P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.

    Other hazards which do not result in classification

    no data available

    Handling and Storage

    Precautions for safe handling

    Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

    Conditions for safe storage, including any incompatibilities

    Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

  • Seller Information
    Business Type:

    Trader

    Main Products:

    3-(1-Naphthoyl)indole

    Location:

    RONGSHENG BEIYUANDAJIE 9, LICHENG DISTRICT,JINAN, SHANDONG CHINA

    Year of Establishment:

    2022

    Jinan Topfull Chemical Co., Ltd. is a global chemical Industrial and focuses on advanced chemical technology. Specialized in Cosmetic materials, water treatment, fine chemicals and so on. We are looking forward to working together with the people of all circles at home and abroad to seek common development!
  • Country Product Purchase Quantity Date Posted
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