Merck 5
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CAS No.:
457081-03-7
Content:
95%
Price valid (until):
2026-08-03
Company Type:
Manufactory
Location:
United States
Qualification:
Main Products:
Coenzymes,Inhibito,Enzymes,Zymogens,Substrates,Native Microorganism Creatine Amidinohydrolase
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Product Description
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Seller Information
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Description
ProductName Merck 5 Cat No CEI-1097 Description Merck 5 is a potent and reversible ATP-competitive inhibitor of the JAK kinases Jak1, Jak2, Jak3, and Tyk2. It also blocks IL2 and IL4 dependent proliferation of CTLL cells and inhibits the phosphorylation of STAT5. Abbr Merck 5(Jaks ) Product Overview ATP-competitive inhibitor of the JAK kinases Jak1, Jak2, Jak3, and Tyk2. CAS No 457081-03-7 Molecular Weight 309.34 Purity > 95% Stability 2 years -20 centigrade Powder1 month -4 centigrade in DMSOMore than one month -80 centigrade in DMSO Storage 4 centigrade Targets Jaks Molecular Formula C18H16FN3O Chemical Name 6-dihydro-7H-Benz[h]imidazo[4,5-f]isoquinolin-7-one, 2-(1,1-dimethylethyl)-9-fluoro-1 Solubility DMSO > 112mg/mL Water >1mg/mL Ethanol > 4mg/mL category Specialty Chemicals(c26) cas_num 457081-03-7 Basic Info-
Product Name:
JAKINHIBITORI
Other Name:Merck-5;MERk-5;2-(tert-butyl)-9-fluoro-3H-benzo[h]iMidazo[4,5-f]isoquinolin-7(6H)-one;Pyridone 6（JAK INHIBITOR I）;JAK Inhibitor I - CAS 457081-03-7 - Calbiochem;JAK Inhibitor I(Merck 5);MERCK 5;MERCK5;CS-665
CAS No.:457081-03-7
Molecular Formula:C18H16FN3O
Molecular Weight:309.34
Categories:
Characteristics-
PSA:
61.80000
XLogP3:4.40650
Density:1.328
Boiling Point:646.5±55.0 °C(Predicted)
Flash Point:344.78ºC
PKA:11.35±0.20
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Seller Information
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Business Type:
Manufactory
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Main Products:
Coenzymes,Inhibito,Enzymes,Zymogens,Substrates,Native Microorganism Creatine Amidinohydrolase
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Location:
Shirley, New York 11967, USA
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Payment Terms:
TT against copy of documents,D/P
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Average lead Time:
15
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Total Annual Revenue:
$1 million-$2.5 million
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Year of Establishment:
2004
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