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Merck 5

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CAS No.:

457081-03-7

Content:

95%

Sample Available:

Yes

Price valid (until):

2026-11-22

Company Type:
Manufactory
Location:
United States
Payment Terms:
TT against copy of documents,D/P
Average Lead Time:
15 days
Qualification:
Main Products:

Coenzymes,Inhibito,Enzymes,Zymogens,Substrates,Native Microorganism Creatine Amidinohydrolase

  • Product Details

  • Seller Information

  • Description
    ProductName Merck 5
    Cat No CEI-1097
    Description Merck 5 is a potent and reversible ATP-competitive inhibitor of the JAK kinases Jak1, Jak2, Jak3, and Tyk2. It also blocks IL2 and IL4 dependent proliferation of CTLL cells and inhibits the phosphorylation of STAT5.
    Abbr Merck 5(Jaks )
    Product Overview ATP-competitive inhibitor of the JAK kinases Jak1, Jak2, Jak3, and Tyk2.
    CAS No 457081-03-7
    Molecular Weight 309.34
    Purity > 95%
    Stability 2 years -20 centigrade Powder1 month -4 centigrade in DMSOMore than one month -80 centigrade in DMSO
    Storage 4 centigrade
    Targets Jaks
    Molecular Formula C18H16FN3O
    Chemical Name 6-dihydro-7H-Benz[h]imidazo[4,5-f]isoquinolin-7-one, 2-(1,1-dimethylethyl)-9-fluoro-1
    Solubility DMSO > 112mg/mL Water >1mg/mL Ethanol > 4mg/mL
    category Specialty Chemicals(c26)
    cas_num 457081-03-7

    Basic Info
    Product Name:

    JAKINHIBITORI

    Other Name:

    Merck-5;MERk-5;2-(tert-butyl)-9-fluoro-3H-benzo[h]iMidazo[4,5-f]isoquinolin-7(6H)-one;Pyridone 6(JAK INHIBITOR I);JAK Inhibitor I - CAS 457081-03-7 - Calbiochem;JAK Inhibitor I(Merck 5);MERCK 5;MERCK5;CS-665

    CAS No.:

    457081-03-7

    Molecular Formula:

    C18H16FN3O

    Molecular Weight:

    309.34

    Categories:

    Characteristics
    PSA:

    61.80000

    XLogP3:

    4.40650

    Density:

    1.328

    Boiling Point:

    646.5±55.0 °C(Predicted)

    Flash Point:

    344.78ºC

    PKA:

    11.35±0.20

  • Seller Information
    Business Type:

    Manufactory

    Main Products:

    Coenzymes,Inhibito,Enzymes,Zymogens,Substrates,Native Microorganism Creatine Amidinohydrolase

    Location:

    Shirley, New York 11967, USA

    Payment Terms:

    TT against copy of documents,D/P

    Average lead Time:

    15 days

    Total Annual Revenue:

    $1 million-$2.5 million

    Year of Establishment:

    2004

    Creative Enzymes is a leading Manufactory supplier of Proline dipeptidase, Glucoamylase, BenzaMide, N-1H-pyrrolo[2,3-c]pyridin-5-yl- based in America. With a commitment to quality and customer satisfaction, Creative Enzymes has become a trusted name in the industry. Our product line includes a range of high-quality Proline dipeptidase, Glucoamylase, BenzaMide, N-1H-pyrrolo[2,3-c]pyridin-5-yl-, which are available at competitive prices. Creative Enzymes has established itself as a reliable supplier of chemical products on the echemi.com.

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