Purvalanol B
212844-54-7
95%
2026-08-08
Coenzymes,Inhibito,Enzymes,Zymogens,Substrates,Native Microorganism Creatine Amidinohydrolase
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Product Description
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Seller Information
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Description
ProductName Purvalanol B Cat No CEI-1104 Description Cyclin-dependent kinase inhibitor with IC50 values of 6, 6, 9, > 10,000, and 6 nM for cdc2/cyclin B, cdk2/cyclin A, cdk2/cyclin E, cdk4/cyclin D1 and cdk5-p35 respectively. Purvalanol B has also been shown to have antiproliferative properties, mediated by p42/p44 MAPK. Abbr Purvalanol B(CDK1, cyclin B, CDK2, CCNA2, cyclin E, CDK4, CCND1, CDK5, IL12A, ) Alias CDC2, CDC28A, P34CDC2 Product Overview Cyclin-dependent kinase inhibitor CAS No 212844-54-7 Molecular Weight 432.9 Purity > 95% Stability 2 years -20 centigrade Powder1 month -4 centigrade in DMSOMore than one month -80 centigrade in DMSO Storage 4 centigrade Synonyms CDC2, CDC28A, P34CDC2 Targets cdc2/cyclin B, cdk2/cyclin A, cdk2/cyclin E, cdk4/cyclin D1, cdk5-p35 Molecular Formula C20H25ClN6O3 Chemical Name (R)-2-chloro-4-(2-(1-hydroxy-3-methylbutan-2-ylamino)-9-isopropyl-9H-purin-6-ylamino)benzoic acid Solubility DMSO > 112mg/mL Water >1mg/mL Ethanol > 4mg/mL category Specialty Chemicals(c26) cas_num 212844-54-7 Basic Info-
Product Name:
Purvalanol B
Other Name:Benzoic acid,2-chloro-4-[[2-[[(1R)-1-(hydroxymethyl)-2-methylpropyl]amino]-9-(1-methylethyl)-9H-purin-6-yl]amino]-;2-Chloro-4-[[2-[[(1R)-1-(hydroxymethyl)-2-methylpropyl]amino]-9-(1-methylethyl)-9H-purin-6-yl]amino]benzoic acid;Purvalanol B;NG 95
CAS No.:212844-54-7
Molecular Formula:C20H25ClN6O3
InChIKeys:InChIKey=ZKDXRFMOHZVXSG-HNNXBMFYSA-N
Molecular Weight:432.90400
Exact Mass:432.90
Categories:
Characteristics-
PSA:
125.19000
XLogP3:4.07720
Density:1.43g/cm3
Melting Point:55.9 °C
Boiling Point:666ºC
Flash Point:353.3ºC
Refractive Index:1.672
Storage Conditions:-20ºC
Vapor Pressure:2.37E-18mmHg at 25°C
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Seller Information
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Business Type:
Manufactory
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Main Products:
Coenzymes,Inhibito,Enzymes,Zymogens,Substrates,Native Microorganism Creatine Amidinohydrolase
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Location:
Shirley, New York 11967, USA
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Payment Terms:
TT against copy of documents,D/P
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Average lead Time:
15
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Total Annual Revenue:
$1 million-$2.5 million
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Year of Establishment:
2004
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Country Product Purchase Quantity Date Posted Post an enquiry for this product