SMI-4a
438190-29-5
95%
2026-07-11
Coenzymes,Inhibito,Enzymes,Zymogens,Substrates,Native Microorganism Creatine Amidinohydrolase
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Product Description
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Seller Information
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Description
ProductName SMI-4a Cat No CEI-1120 Description SMI-4a is a novel, ATP-competitive inhibitor of Pim kinases.
It kills a wide range of both myeloid and lymphoid cell lines with precursor T-cell lymphoblastic leukemia/lymphoma (pre-T-LBL/T-ALL) being highly sensitive.Abbr SMI-4a(PIM1) Alias PIM Product Overview Inhibitor of Pim kinases CAS No 438190-29-5 Molecular Weight 273.23 Purity > 95% Stability 2 years -20 centigrade Powder1 month -4 centigrade in DMSOMore than one month -80 centigrade in DMSO Storage 4 centigrade Synonyms PIM Targets PIM Molecular Formula C11H6F3NO2S Chemical Name (E)-5-(3-(trifluoromethyl)benzylidene)thiazolidine-2,4-dione Solubility DMSO > 112mg/mL Water >1mg/mL Ethanol > 4mg/mL category Inhibitors(c1514) cas_num 438190-29-5 Basic Info-
Product Name:
(5Z)-5-[[3-(Trifluoromethyl)phenyl]methylene]-2,4-thiazolidinedione
Other Name:(5Z)-5-[[3-(Trifluoromethyl)phenyl]methylene]-2,4-thiazolidinedione;TCS PIM-1 4a;SMI-4a;(Z)-5-(3-(trifluoroMethyl)benzylidene)thiazolidine-2,4-dione;2,4-Thiazolidinedione, 5-[[3-(trifluoromethyl)phenyl]methylene]-, (5Z)-;TCS PIM-1 4a, >=98%;(5E)-5-{[3-(trifluoromethyl)phenyl]methylidene}-1,3-thiazolidine-2,4-dione;(Z)-SMI-4a
CAS No.:438190-29-5
Molecular Formula:C11H6F3NO2S
InChIKeys:NGJLOFCOEOHFKQ-YVMONPNESA-N
Molecular Weight:273
Exact Mass:273.007
Categories:
Characteristics-
PSA:
71.5
XLogP3:3.1
Appearance:white to beige
Water Solubility:DMSO: >10mg/mL
Storage Conditions:Desiccate at +4°C
Hazard IdentificationClassification of the substance or mixture
Skin sensitization, Category 1
Eye irritation, Category 2
GHS label elements, including precautionary statements
Pictogram(s) 
Signal word Warning
Hazard statement(s) H317 May cause an allergic skin reaction
H319 Causes serious eye irritation
Precautionary statement(s) Prevention P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P272 Contaminated work clothing should not be allowed out of the workplace.
P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...
P264 Wash ... thoroughly after handling.
Response P302+P352 IF ON SKIN: Wash with plenty of water/...
P333+P317 If skin irritation or rash occurs: Get medical help.
P321 Specific treatment (see ... on this label).
P362+P364 Take off contaminated clothing and wash it before reuse.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
Storage none
Disposal P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.
Other hazards which do not result in classification
no data available
Handling and StoragePrecautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.
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Seller Information
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Business Type:
Manufactory
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Main Products:
Coenzymes,Inhibito,Enzymes,Zymogens,Substrates,Native Microorganism Creatine Amidinohydrolase
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Location:
Shirley, New York 11967, USA
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Payment Terms:
TT against copy of documents,D/P
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Average lead Time:
15
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Total Annual Revenue:
$1 million-$2.5 million
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Year of Establishment:
2004
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Country Product Purchase Quantity Date Posted Post an enquiry for this product