Y-39983 dihydrochloride
173897-44-4
0.98%
2026-07-23
Coenzymes,Inhibito,Enzymes,Zymogens,Substrates,Native Microorganism Creatine Amidinohydrolase
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Product Description
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Seller Information
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Description
ProductName Y-39983 dihydrochloride Cat No CEI-1588 Product Overview Y-39983 dihydrochloride is a novel and selective inhibitor of ROCK family with IC50 value of 3.6nM for ROCK. Y-39983 dihydrochloride has shown a selective inhibitor of Rho-associated coiled coil-forming protein kinase (ROCK) with IC50 values of 3.6nM, 0.42μM and 0.81μM for ROCK, PKC and CaMKII, respectively. Apart from these, Y-39983 has been reported to relax the ciliary arteries of precontracted isolated rabbit in vitro. In addition, Y-39983 has been found to increase optic-nerve-head blood flow by laser speckle flowmetry. Moreover, Y-39983 lowered the intraocular pressure (IOP) in a dose-dependent fashion in the eyes of rabbits and monkeys. CAS No 173897-44-4 Molecular Weight 353.25 Purity 0.98 Storage Store at-20°C Targets ROCK Molecular Formula C16H18Cl2N4O Chemical Name 4-[(1R)-1-aminoethyl]-N-(1H-pyrrolo[2,3-b]pyridin-4-yl)benzamide; dihydrochloride Solubility Soluble in DMSO Shipping Conditions Evaluation sample solution: ship with blue ice. All other available size: ship with RT, or blue ice upon request category Specialty Chemicals(c26) cas_num 173897-44-4 Basic Info-
Product Name:
(R)-4-(1-aMinoethyl)-N-(1H-pyrrolo[2,3-b]pyridin-4-yl)benzaMide dihydrochloride
Other Name:(R)-4-(1-aMinoethyl)-N-(1H-pyrrolo[2,3-b]pyridin-4-yl)benzaMide dihydrochloride;Y-33075 (dihydrochloride);Y 39983 2HCL;Y-33075 2HCl;Y 39983, 2 HCl salt;Y39983 HYDROCHLORIDE;Y-33075 HCl;Y39983 dihydrochlortide
CAS No.:173897-44-4
Molecular Formula:C16H18Cl2N4O
InChIKeys:CKFHAVRPVZNMGT-WTVPDBJGNA-N
Molecular Weight:353.24632
Exact Mass:352.0857666
DSSTox ID:DTXSID40609036
Color/Form:White to gray
Categories:
Characteristics-
Critical Temperature & Pressure:
Inert atmosphere,Room Temperature
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Seller Information
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Business Type:
Manufactory
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Main Products:
Coenzymes,Inhibito,Enzymes,Zymogens,Substrates,Native Microorganism Creatine Amidinohydrolase
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Location:
Shirley, New York 11967, USA
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Payment Terms:
TT against copy of documents,D/P
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Average lead Time:
15
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Total Annual Revenue:
$1 million-$2.5 million
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Year of Establishment:
2004
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