PF-5274857
1373615-35-0
95%
2026-08-06
Coenzymes,Inhibito,Enzymes,Zymogens,Substrates,Native Microorganism Creatine Amidinohydrolase
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Product Description
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Seller Information
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Description
ProductName PF-5274857 Cat No CEI-1165 Description PF-5274857 is a potent and selective Smoothened (Smo) antagonist with IC50 and Ki of 5.8 nM and 4.6 nM, respectively. Abbr PF-5274857(SMO) Alias FZD11, Gx, SMOH CAS No 1373615-35-0 Molecular Weight 436.96 Purity > 95% Storage 4 centigrade Synonyms FZD11, Gx, SMOH Targets Smoothened (Smo) IC50 5.8 nM Molecular Formula C20H25ClN4O3S Chemical Name 5'-chloro-3,5-dimethyl-2'-{4-[3-(methylsulfonyl)propanoyl]piperazin-1-yl}-2,4'-bipyridine category Inhibitors(c1514) cas_num 1373615-35-0 Basic Info-
Product Name:
pf-5274857
Other Name:pf-5274857;1-(4-(5-chloro-4-(3,5-diMethylpyridin-2-yl)pyridin-2-yl)piperazin-1-yl)-3-(Methylsulfonyl)propan-1-one;1-[4-(5′-Chloro-3,5-dimethyl-2,4′-bipyridin-2′-yl)piperazin-1-yl] -3- (methylsulfonyl)propan-1-one hydrochloride;PF-5274857 hydrochloride;1-[4-(5'-Chloro-3,5-dimethyl[2,4'-bipyridin]-2'-yl)-1-piperazinyl]-3-(methylsulfonyl)-1-propanone;1-(4-(5-Chloro-4-(3,5-dimethylpyridin-2-yl)pyridin-2-yl)piperazin-1-yl)-3-(methylsulfonyl)prop
CAS No.:1373615-35-0
Molecular Formula:C20H25ClN4O3S
InChIKeys:BBVNTTZIOTWDSV-UHFFFAOYSA-N
Molecular Weight:436.9555
Exact Mass:436.134
EC Number:-0
DSSTox ID:DTXSID70719132
Categories:
Characteristics-
PSA:
91.8
XLogP3:1.8
Appearance:white to beige
Water Solubility:H2O: soluble3mg/mL, clear (warmed)
Storage Conditions:room temp
Hazard IdentificationClassification of the substance or mixture
no data available
GHS label elements, including precautionary statements
Pictogram(s) no data available Signal word no data available
Hazard statement(s) no data available
Precautionary statement(s) Prevention no data available
Response no data available
Storage no data available
Disposal no data available
Other hazards which do not result in classification
no data available
Handling and StoragePrecautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.
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Seller Information
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Business Type:
Manufactory
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Main Products:
Coenzymes,Inhibito,Enzymes,Zymogens,Substrates,Native Microorganism Creatine Amidinohydrolase
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Location:
Shirley, New York 11967, USA
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Payment Terms:
TT against copy of documents,D/P
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Average lead Time:
15
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Total Annual Revenue:
$1 million-$2.5 million
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Year of Establishment:
2004
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Country Product Purchase Quantity Date Posted Post an enquiry for this product