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1-Fluoro-2,4-dinitrobenzene

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CAS No.:

70-34-8

Content:

99%

Sample Available:

Yes

Price valid (until):

2026-11-25

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Creative Enzymes

Company Type:

Manufactory

Location:

United States

Payment Terms:

TT against copy of documents,D/P

Average Lead Time:

15 days

Qualification:

Main Products:

Coenzymes,Inhibito,Enzymes,Zymogens,Substrates,Native Microorganism Creatine Amidinohydrolase

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Product Details
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Description

ProductName	1-Fluoro-2,4-dinitrobenzene
Cat No	CSUB-0636
Description	1-Fluoro-2,4-dinitrobenzene is a chemical used for polypeptide sequencing.
Applications	An alkylating agent used in elucidating amino acid sequence in proteins
Form	Low-Melting Solid
CAS No	70-34-8
Molecular Weight	186.1
Purity	>99%
Storage	Desiccate at 4° C
Synonyms	Sanger’s Reagent; Dinitrofluorobenzene; DNFB
Molecular Formula	C6H3FN2O4
MDL Number	MFCD00007056
Melting Point	24-30° C
Solubility	Soluble in chloroform, benzene, ether and propylene glycol.
category	Analysis Reagents(c2412)
cas_num	70-34-8

ECHEMI Editorial Reference

Yellow solid
2,4-dinitrofluorobenzene appears as clear yellow crystals or yellow crystalline solid. (NTP, 1992)
2,4-dinitrofluorobenzene appears as clear yellow crystals or yellow crystalline solid. (NTP, 1992)|1-fluoro-2,4-dinitrobenzene is the organofluorine compound that is benzene with a fluoro substituent at the 1-position and two nitro substituents in the 2- and 4-positions. It has a role as an agrochemical, a protein-sequencing agent, an EC 2.7.3.2 (creatine kinase) inhibitor, an allergen, a chromatographic reagent and a spectrophotometric reagent. It is a C-nitro compound and an organofluorine compound.|Dinitrofluorobenzene is an aromatic hydrocarbon composed of a benzene ring linked to two nitro groups and one fluoride group that is used for N-terminal amino acid sequencing by the Sanger method. In vitro, dinitrofluorobenzene (DNFB) reacts with the amine group in amino acids to produce dinitrophenyl (DNP)-amino acids. Then the sample is subjected to acid hydrolysis. Under these conditions, the peptide bonds are broken but the DNP-amino acid bonds remain intact. The DNP-amino acids can be recovered and their identities can be determined through the use of various chromatography techniques. This reagent can also be used to distinguish the reduced and oxidized forms of glutathione and cysteine.|Irritants and reagents for labeling terminal amino acid groups.

Basic Info

Product Name:

Dinitrofluorobenzene

Other Name:

Benzene,1-fluoro-2,4-dinitro-;1-Fluoro-2,4-dinitrobenzene;DFB;2,4-Dinitrofluorobenzene;2,4-Dinitro-1-fluorobenzene;DNFB;FDNB;Dinitrofluorobenzene;Fluorodinitrobenzene;2,4-Dinitrobenzene fluoride;2,4-Dinitrophenyl fluoride;4-Fluoro-1,3-dinitrobenzene;NSC 33519;Sanger's reagent

CAS No.:

70-34-8

Molecular Formula:

C6H3FN2O4

InChIKeys:

InChIKey=LOTKRQAVGJMPNV-UHFFFAOYSA-N

Molecular Weight:

186.1

Exact Mass:

186.10

BRN:

398632

EC Number:

200-734-3

UNII:

D241E059U6

NSC Number:

33519

UN Number:

2811

DSSTox ID:

DTXSID8025331

NCI Thesaurus Code:

C440

Color/Form:

Pale yellow crystals from ether

HScode:

29049085

Categories:

Analysis Reagents

Characteristics

PSA:

91.6

XLogP3:

1.83 (est)

Appearance:

Yellow to brownish Liquid or Low Melting Crystals

Density:

1.4718 g/cm³ @ Temp: 54 °C

Melting Point:

25.8 °C

Boiling Point:

296 °C

Flash Point:

>230 °F

Refractive Index:

1.585

Water Solubility:

H2O: 400 mg/L (25 ºC);chloroform: 0.1 g/mL, clear

Storage Conditions:

2-8°C

Vapor Pressure:

0.00237 mm Hg at 25 deg C (est)

Toxicity:

Oral-rat LDL0: 50 mg/kg; Subcutaneous-mouse LDL0: 100 mg/kg

Flammability characteristics:

Open flame is flammable; nitrogen oxide and fluoride are liberated by heat

Explosive limit:

Solutions in ether may explode when evaporated.

Henrys Law Constant:

Henry's Law constant = 9.8X10-8 atm-cu m/mole at 25 °C (est)

Experimental Properties:

Hydroxyl radical reaction rate constant = 3.8X10-14 cu cm/molecule-sec at 25 °C (est)

Air and Water Reactions:

Slightly soluble in water.

Reactive Group:

Nitro, Nitroso, Nitrate, and Nitrite Compounds, Organic

Reactivity Profile:

Reacts with oxidizing agents (NTP, 1992). When air was admitted after vacuum evaporation of an ether peroxide solution, a violent explosion occurred. A halogenated aromatic nitro compound. Aromatic nitro compounds range from slight to strong oxidizing agents. If mixed with reducing agents, including hydrides, sulfides and nitrides, they may begin a vigorous reaction that culminates in a detonation. The aromatic nitro compounds may explode in the presence of a base such as sodium hydroxide or potassium hydroxide even in the presence of water or organic solvents. The explosive tendencies of aromatic nitro compounds are increased by the presence of multiple nitro groups.

See More Dinitrofluorobenzene Properties 

Hazard Identification

Classification of the substance or mixture

Acute toxicity - Category 4, Oral

Skin irritation, Category 2

Skin sensitization, Category 1

Eye irritation, Category 2

Specific target organ toxicity â single exposure, Category 3

Specific target organ toxicity â repeated exposure, Category 2

GHS label elements, including precautionary statements

Precautionary statement(s)
Pictogram(s)
Signal word	Warning
Hazard statement(s)	H302 Harmful if swallowed H315 Causes skin irritation H317 May cause an allergic skin reaction H319 Causes serious eye irritation H335 May cause respiratory irritation H373 May cause damage to organs through prolonged or repeated exposure
Prevention	P264 Wash ... thoroughly after handling. P270 Do not eat, drink or smoke when using this product. P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/... P261 Avoid breathing dust/fume/gas/mist/vapours/spray. P272 Contaminated work clothing should not be allowed out of the workplace. P271 Use only outdoors or in a well-ventilated area. P260 Do not breathe dust/fume/gas/mist/vapours/spray.
Response	P301+P317 IF SWALLOWED: Get medical help. P330 Rinse mouth. P302+P352 IF ON SKIN: Wash with plenty of water/... P321 Specific treatment (see ... on this label). P332+P317 If skin irritation occurs: Get medical help. P362+P364 Take off contaminated clothing and wash it before reuse. P333+P317 If skin irritation or rash occurs: Get medical help. P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing. P319 Get medical help if you feel unwell.
Storage	P403+P233 Store in a well-ventilated place. Keep container tightly closed. P405 Store locked up.
Disposal	P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.

Other hazards which do not result in classification

no data available

Handling and Storage

Precautions for safe handling

Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

Conditions for safe storage, including any incompatibilities

Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

See More Dinitrofluorobenzene Safety Data Sheet 

Seller Information

Business Type:
Manufactory

Main Products:
Coenzymes,Inhibito,Enzymes,Zymogens,Substrates,Native Microorganism Creatine Amidinohydrolase

Location:
Shirley, New York 11967, USA

Payment Terms:
TT against copy of documents,D/P

Average lead Time:
15 days

Total Annual Revenue:
$1 million-$2.5 million

Year of Establishment:
2004

Creative Enzymes is a leading Manufactory supplier of Proline dipeptidase, Glucoamylase, BenzaMide, N-1H-pyrrolo[2,3-c]pyridin-5-yl- based in America. With a commitment to quality and customer satisfaction, Creative Enzymes has become a trusted name in the industry. Our product line includes a range of high-quality Proline dipeptidase, Glucoamylase, BenzaMide, N-1H-pyrrolo[2,3-c]pyridin-5-yl-, which are available at competitive prices. Creative Enzymes has established itself as a reliable supplier of chemical products on the echemi.com.
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1-Fluoro-2,4-dinitrobenzene

Product Details

Seller Information

Classification of the substance or mixture

GHS label elements, including precautionary statements

Other hazards which do not result in classification

Precautions for safe handling

Conditions for safe storage, including any incompatibilities

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