cob(I)yrinic acid a,c-diamide adenosyltransferase
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CAS No.:
37277-84-2
Price valid (until):
2026-10-18
Company Type:
Manufactory
Location:
United States
Payment Terms:
TT against copy of documents,D/P
Average Lead Time:
15 days
Qualification:
Main Products:
Coenzymes,Inhibito,Enzymes,Zymogens,Substrates,Native Microorganism Creatine Amidinohydrolase
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Description
ProductName cob(I)yrinic acid a,c-diamide adenosyltransferase Cat No EXWM-2753 Description The corrinoid adenosylation pathway comprises three steps: (i) reduction of Co(III) to Co(II) by a one-electron transfer. This can be carried out by EC 1.16.1.3, aquacobalamin reductase or non-enzymically in the presence of dihydroflavin nucleotides. (ii) Co(II) is reduced to Co(I) in a second single-electron transfer by EC 1.16.1.4, cob(II)alamin reductase and (iii) the Co(I) conducts a nucleophilic attack on the adenosyl moiety of ATP to leave the cobalt atom in a Co(III) state (EC 2.5.1.17). The enzyme responsible for the adenosylation reaction is the product of the gene cobO in the aerobic bacterium Pseudomonas denitrificans and of the gene cobA in the anaerobic bacterium Salmonella typhimurium. In P. denitrificans, the enzyme shows specificity for cobyrinic acid a,c-diamide and the corrinoids that occur later in the biosynthetic pathway whereas CobA seems to have broader specificity. While CobA has a preference for ATP and Mn2+, it is able to transfer a variety of nucleosides to the cobalt, including CTP, UTP and GTP, in decreasing order of preference and to use Mg2+ instead of Mn2+. Form Liquid or lyophilized powder Enzyme Commission Number EC 2.5.1.17 CAS No 37277-84-2 Storage Store it at +4 ºC for short term. For long term storage, store it at -20 ºC～-80 ºC. Synonyms CobA; CobO; ATP:corrinoid adenosyltransferase; cob(I)alamin adenosyltransferase; aquacob(I)alamin adenosyltransferase; aquocob(I)alamin vitamin B12s adenosyltransferase; ATP:cob(I)alamin Coβ-adenosyltransferase Reaction (1) ATP + cob(I)yrinic acid a,c-diamide = triphosphate + adenosylcob(III)yrinic acid a,c-diamide; (2) ATP + cobinamide = triphosphate + adenosylcobinamide Notes This item requires custom production and lead time is between 5-9 weeks. We can custom produce according to your specifications. cas_num 37277-84-2 category Specialty Chemicals(c26) Basic Info-
Product Name:
cob(I)yrinic acid a,c-diamide adenosyltransferase
CAS No.:37277-84-2
Categories:
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Seller Information
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Business Type:
Manufactory
-
Main Products:
Coenzymes,Inhibito,Enzymes,Zymogens,Substrates,Native Microorganism Creatine Amidinohydrolase
-
Location:
Shirley, New York 11967, USA
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Payment Terms:
TT against copy of documents,D/P
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Average lead Time:
15 days
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Total Annual Revenue:
$1 million-$2.5 million
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Year of Establishment:
2004
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