Company Type:
Manufactory
Location:
United States
Qualification:
Main Products:
Coenzymes,Inhibito,Enzymes,Zymogens,Substrates,Native Microorganism Creatine Amidinohydrolase
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Product Description
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Seller Information
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Description
ProductName caspase-6 Cat No EXWM-4234 Description Caspase-6 is an effector/executioner caspase, as are caspase-3 (EC 3.4.22.56) and caspase-7 (EC 3.4.22.60). These caspases are responsible for the proteolysis of the majority of cellular polypeptides [e.g. poly(ADP-ribose) polymerase (PARP)], which leads to the apoptotic phenotype. Caspase-6 can cleave its prodomain to produce mature caspase-6, which directly activates caspase-8 (EC 3.4.22.61) and leads to the release of cytochrome c from the mitochondria. The release of cytochrome c is an essential component of the intrinsic apoptosis pathway. The enzyme can also cleave and inactivate lamins, the intermediate filament scaffold proteins of the nuclear envelope, leading to nuclear fragmentation in the final phases of apoptosis. Belongs in peptidase family C14. Form Liquid or lyophilized powder Enzyme Commission Number EC 3.4.22.59 CAS No 182372-15-2 Storage Store it at +4 ºC for short term. For long term storage, store it at -20 ºC～-80 ºC. Synonyms CASP-6; apoptotic protease Mch-2; Mch2 Reaction Strict requirement for Asp at position P1 and has a preferred cleavage sequence of Val-Glu-His-Asp┼ Notes This item requires custom production and lead time is between 5-9 weeks. We can custom produce according to your specifications. category Specialty Chemicals(c26) cas_num 182372-15-2 Basic Info-
Product Name:
CASPASE-6
CAS No.:182372-15-2
Categories:
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Seller Information
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Business Type:
Manufactory
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Main Products:
Coenzymes,Inhibito,Enzymes,Zymogens,Substrates,Native Microorganism Creatine Amidinohydrolase
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Location:
Shirley, New York 11967, USA
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Payment Terms:
TT against copy of documents,D/P
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Average lead Time:
15
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Total Annual Revenue:
$1 million-$2.5 million
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Year of Establishment:
2004
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