high quality FK506(Tacrolimus) 99% transparent liquid KANBEI
HALAL ISO 2 Inquiries
104987-11-3
Industrial Grade
99%
QINGDAO
KANBEI
25kg drum
2023-10-08
PVC resin,pvc paste resin,melamine
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Product Description
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Seller Information
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Inquiry History
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DescriptionECHEMI Editorial ReferenceTacrolimus is a macrocyclic lactone with potent immunosuppressive properties. Tacrolimus binds to FK506 binding protein (FKBP) to form a complex and inhibits calcineurin phosphatase.CertificatesBasic Info
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Product Name:
Tacrolimus
Other Name:15,19-Epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclotricosine-1,7,20,21(4H,23H)-tetrone,5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a-hexadecahydro-5,19-dihydroxy-3-[(1E)-2-[(1R,3R,4R)-4-hydroxy-3-methoxycyclohexyl]-1-methylethenyl]-14,16-dimethoxy-4,10,12,18-tetramethyl-8-(2-propen-1-yl)-,(3S,4R,5S,8R,9E,12S,14S,15R,16S,18R,19R,26aS)-;15,19-Epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclotricosine-1,7,20,21(4H,23H)-tetrone,5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a-hexadecahydro-5,19-dihydroxy-3-[2-(4-hydroxy-3-methoxycyclohexyl)-1-methylethenyl]-14,16-dimethoxy-4,10,12,18-tetramethyl-8-(2-propenyl)-,[3S-[3R*[E(1S*,3S*,4S*)],4S*,5R*,8S*,9E,12R*,14R*,15S*,16R*,18S*,19S*,26aR*]]-;15,19-Epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclotricosine-1,7,20,21(4H,23H)-tetrone,5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a-hexadecahydro-5,19-dihydroxy-3-[(1E)-2-[(1R,3R,4R)-4-hydroxy-3-methoxycyclohexyl]-1-methylethenyl]-14,16-dimethoxy-4,10,12,18-tetramethyl-8-(2-propenyl)-,(3S,4R,5S,8R,9E,12S,14S,15R,16S,18R,19R,26aS)-;(3S,4R,5S,8R,9E,12S,14S,15R,16S,18R,19R,26aS)-5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a-Hexadecahydro-5,19-dihydroxy-3-[(1E)-2-[(1R,3R,4R)-4-hydroxy-3-methoxycyclohexyl]-1-methylethenyl]-14,16-dimethoxy-4,10,12,18-tetramethyl-8-(2-propen-1-yl)-15,19-epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclotricosine-1,7,20,21(4H,23H)-tetrone;FR 900506;FK 506;Tsukubaenolide;L 679934;Fujimycin;(-)-FK 506;Tacrolimus;Prograf;Protopic;Advagraf;TacroBell;FK506;Prograph;Envarsus XR;Astagraf XL;Hecoria;Tacropic;Protopy;Modigraf;Envarsus
CAS No.:104987-11-3
Molecular Formula:C44H69NO12
InChIKeys:InChIKey=QJJXYPPXXYFBGM-LFZNUXCKSA-N
Molecular Weight:804.02
Exact Mass:804.02
EC Number:1308068-626-2
DSSTox ID:DTXSID5046354
Categories:
Characteristics-
PSA:
178 Ų
XLogP3:3.3
Appearance:white solid
Density:1.2±0.1 g/cm3
Melting Point:113-115°C
Flash Point:2℃
Refractive Index:1.549
Water Solubility:Freely soluble in DMSO or ethanol. Poorly soluble in water.soluble in dimethyl sulfoxide, ethanol, water, acetone, chloroform, ethyl acetate, ether, methanol and dimethyl formamide.DMSO: >3 mg/mL
Storage Conditions:−20°C
Vapor Pressure:8.37X10-32 mm Hg at 25 °C (est)
Henrys Law Constant:Henry's Law constant = 4.74X10-24 atm-cum/mol at 25 °C (est)
Dissociation Constants:pKa1 = 2.94; pKa2 = 9.95; pKa3 = 14.07 (est)
Experimental Properties:Hydroxyl radical reaction rate constant = 3.81X10-10 cu cm/molec-sec at 25 °C (est)|Ozone radical reaction rate constant = 8.719X10-16 cu cm/molec-sec at 25 °C (est)
Hazard IdentificationClassification of the substance or mixture
Acute toxicity - Category 3, Oral
Reproductive toxicity, Category 2
Specific target organ toxicity â repeated exposure, Category 1
GHS label elements, including precautionary statements
Pictogram(s) 
Signal word Danger
Hazard statement(s) H301 Toxic if swallowed
H361 Suspected of damaging fertility or the unborn child
H372 Causes damage to organs through prolonged or repeated exposure
Precautionary statement(s) Prevention P264 Wash ... thoroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P203 Obtain, read and follow all safety instructions before use.
P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...
P260 Do not breathe dust/fume/gas/mist/vapours/spray.
Response P301+P316 IF SWALLOWED: Get emergency medical help immediately.
P321 Specific treatment (see ... on this label).
P330 Rinse mouth.
P318 IF exposed or concerned, get medical advice.
P319 Get medical help if you feel unwell.
Storage P405 Store locked up.
Disposal P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.
Other hazards which do not result in classification
no data available
Handling and StoragePrecautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.
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Seller Information
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Business Type:
Trader
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Main Products:
PVC resin,pvc paste resin,melamine
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Location:
Room 405, Unit 2, Building 1, Taiji Mansion, No. 38, Nanyang Road, Jinshui District, Zhengzhou City, Henan Province
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Payment Terms:
TT against copy of documents,L/C
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Average lead Time:
90 days
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Total Annual Revenue:
$5 million-$10 million
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Total Employees:
11-50
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Year of Establishment:
2022
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Inquiry History2 Inquiries
Country Product Purchase Quantity Date Posted 
Uzbekistan
China GMP Factory Direct Supply 99% Purity Tacrolimus FK-506 powder CAS 104987-11-3 Sinoway
1 KG Oct 12, 2023 
Saudi Arabia
Tacrolimus
10 G Sep 14, 2024 Post an enquiry for this product
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