Doxofylline Impurity 16
1 Inquiries
603-00-9
25
2023-02-27
Chemical Pesticides,Food Additives,Agrochemicals,Active Pharm Ingredients,Flavors and Fragrances,Chemical Catalyst
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Product Description
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Seller Information
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Inquiry History
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DescriptionECHEMI Editorial ReferenceProxyphylline is a methylxanthine derivative clinical used as cardiac stimulant, vasodilator and bronchodilator.
Proxyphylline is an oxopurine.|Proxyphylline is a methylxanthine and derivative of theophylline. Proxyphylline relaxes smooth muscles, particularly bronchial muscles. This xanthine most likely exerts its effect by inhibiting cAMP or cGMP phosphodiesterases, thereby increasing levels of the second messenger cAMP or cGMP intracellularly. Other mode of actions include an adenosine antagonistic effect on the activity of CD4 lymphocytes and mediator release from mast cells thereby decreasing lung sensitivity to allergens and other substances that cause inflammation. Proxyphylline also acts as a CNS stimulant and exerts a positive chronotropic and inotropic effect on the heart.Basic Info-
Product Name:
Proxyphylline
Other Name:1H-Purine-2,6-dione,3,7-dihydro-7-(2-hydroxypropyl)-1,3-dimethyl-;Theophylline,7-(2-hydroxypropyl)-;3,7-Dihydro-7-(2-hydroxypropyl)-1,3-dimethyl-1H-purine-2,6-dione;Brontyl;1,3-Dimethyl-7-(2-hydroxypropyl)xanthine;7-(β-Hydroxypropyl)theophylline;Proxyphylline;Purophyllin;7-(2-Hydroxypropyl)theophylline;Spasmolysin;Hydroxypropyltheophylline;2-Hydroxypropyl-7-theophylline;Oxypropyltheophylline;β-Hydroxypropyltheophylline;Proxiphylline;7-(β-Hydroxypropyl)-1,3-dimethylxanthine;Theoden;Sanwaphyllin;Sigophyl;Thean;Monophylline;2,6-Dioxo-3,7-dihydro-7-(2-hydroxypropyl)-1,3-dimethylpurine;(±)-Proxyphyllin;Proxy-Retardoral;Theon;Spantin;NSC 163343;86480-51-5
CAS No.:603-00-9
Molecular Formula:C10H14N4O3
InChIKeys:InChIKey=KYHQZNGJUGFTGR-UHFFFAOYSA-N
Molecular Weight:238.24
Exact Mass:238.24
EC Number:210-028-7
NSC Number:759279|163343
DSSTox ID:DTXSID5023536
NCI Thesaurus Code:C80339
ATC Code:R - Respiratory system
HScode:2933990090
Categories:
Characteristics-
PSA:
78.7
XLogP3:-0.8
Density:1.46 g/cm3
Melting Point:135.5 °C
Boiling Point:487.2°C at 3 mmHg
Flash Point:248.5ºC
Refractive Index:1.664
Water Solubility:>35.7 [ug/mL]
Storage Conditions:Refrigerator
Collision Cross Section:149.1 Ų [M+H]+ [CCS Type: TW, Method: calibrated with polyalanine and drug standards]
Hazard IdentificationClassification of the substance or mixture
Acute toxicity - Category 4, Oral
GHS label elements, including precautionary statements
Pictogram(s)
Signal word Warning
Hazard statement(s) H302 Harmful if swallowed
Precautionary statement(s) Prevention P264 Wash ... thoroughly after handling.
P270 Do not eat, drink or smoke when using this product.
Response P301+P317 IF SWALLOWED: Get medical help.
P330 Rinse mouth.
Storage none
Disposal P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.
Other hazards which do not result in classification
no data available
Handling and StoragePrecautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.
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Seller Information
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Business Type:
Manufactory
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Main Products:
Chemical Pesticides,Food Additives,Agrochemicals,Active Pharm Ingredients,Flavors and Fragrances,Chemical Catalyst
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Location:
https://www.dideu.com/en/
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Payment Terms:
TT against copy of documents,D/P,L/C,D/A,O/A,TT against B/L draft before shipment,100% TT in advance
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Average lead Time:
7 days
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Total Annual Revenue:
Above $100 million
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Total Employees:
Above 1000
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Year of Establishment:
2016
Company Certificates-
ISO Certificate
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REACH
">Company Profile -
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Inquiry History1 Inquiries
Country Product Purchase Quantity Date Posted
India
7-(beta-Hydroxypropyl)-theophylline, BP Cas No. : 603-00-9
100 MT Apr 25, 2024 Post an enquiry for this product
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