Manufactory Supply: Top quality Cobicistat/CAS1004316-88-4
1 Inquiries
1004316-88-4
Pharmaceutical Grade
98%
Shanghai
Benoy
According to customer requirements
2023-04-30
intermediate,API
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Product Description
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Seller Information
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Inquiry History
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DescriptionECHEMI Editorial ReferenceCobicistat (GS-9350) is a potent and selective inhibitor of CYP3A with IC50 of 30-285 nM. In September 2013, cobicistat (also known as GS-9350) was approved in the European Union as a pharmacokinetic (PK) enhancer of atazanavir 300 mg once daily or darunavir 800 mg once daily as part of antiretroviral combination therapy in human immunodeficiency virus-1 (HIV-1) infected adults. Cobicistat was discovered from efforts to find a PK enhancer that retained the Cyp3A inhibitory properties of ritonavBasic Info
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Product Name:
Cobicistat
Other Name:2,7,10,12-Tetraazatridecanoic acid,12-methyl-13-[2-(1-methylethyl)-4-thiazolyl]-9-[2-(4-morpholinyl)ethyl]-8,11-dioxo-3,6-bis(phenylmethyl)-,5-thiazolylmethyl ester,(3R,6R,9S)-;Cobicistat;GS 9350;Tybost
CAS No.:1004316-88-4
Molecular Formula:C40H53N7O5S2
InChIKeys:InChIKey=ZCIGNRJZKPOIKD-CQXVEOKZSA-N
Molecular Weight:776.02272
Exact Mass:776.02
UNII:LW2E03M5PG
DSSTox ID:DTXSID00143269
NCI Thesaurus Code:C97360
ATC Code:J05AR|J05|J05AR09|V03AX03|J05AR14|V - Various
Categories:
Characteristics-
PSA:
195
XLogP3:4.77
Density:1.228±0.06 g/cm3 (20 ºC 760 Torr)
Boiling Point:974.5±65.0 °C(Predicted)
Flash Point:543.2±34.3 °C
Refractive Index:1.595
Water Solubility:0.1
Hazard IdentificationClassification of the substance or mixture
no data available
GHS label elements, including precautionary statements
Pictogram(s) no data available Signal word no data available
Hazard statement(s) no data available
Precautionary statement(s) Prevention no data available
Response no data available
Storage no data available
Disposal no data available
Other hazards which do not result in classification
no data available
Handling and StoragePrecautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.
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Seller Information
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Business Type:
Trader
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Main Products:
intermediate,API
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Location:
168 Jianding Road, Jianggan District, Hangzhou City, Zhejiang Province
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Payment Terms:
TT against copy of documents,L/C
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Average lead Time:
1
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Total Annual Revenue:
$5 million-$10 million
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Total Employees:
11-50
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Year of Establishment:
2020
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Inquiry History1 Inquiries
Country Product Purchase Quantity Date Posted
Lithuania
Cobicistat
100 G Jan 24, 2024 Post an enquiry for this product
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