5373-11-5
5373-11-5
kg
2023-05-07
Custom Synthetic Chemicals,Biological Stains,Pharmaceutical Intermediates,Cosmetic Grade Chemicals,Enzyme,Nucleosides
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Product Details
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Seller Information
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DescriptionECHEMI Editorial ReferenceCynaroside is a flavone, a flavonoid-like chemical compound. It is a 7-O-glucoside of luteolin.
Solid
Luteolin 7-O-beta-D-glucoside is a glycosyloxyflavone that is luteolin substituted by a beta-D-glucopyranosyl moiety at position 7 via a glycosidic linkage. It has a role as an antioxidant and a plant metabolite. It is a beta-D-glucoside, a glycosyloxyflavone, a trihydroxyflavone and a monosaccharide derivative. It derives from a luteolin. It is a conjugate acid of a luteolin 7-O-beta-D-glucoside(1-).
Luteolin-7-O-glucoside is a flavonoid that has been found in many Chinese herbs with diverse biological activities. It reduces lactate dehydrogenase (LDH) and caspase-3 activities and production of reactive oxygen species (ROS) and increases cell viability and 14-3-3η protein levels in H9C2 cardiomyocytes after anoxia/reoxygenation injury. Luteoloside blocks 3C protease activity (IC50= 0.36 mM) and reduces the cytopathic effect of enterovirus 71 in rhabdomyosarcoma cells (EC50= 0.43 mM). It inhibits the growth of hepatocellular carcinoma (HCC) cellsin vitro viareduction in ROS accumulation, caspase-1 activity, and expression of the NLRP3 inflammasome and reduces the number of lung metastases in an SMMC-7721 HCC mouse xenograft model when administered at a dose of 2 mg/kg. Luteoloside also reduces acanthosis and expression of epidermal differentiation markers in a mouse model of psoriasis induced by imiquimod .
Off-white powderBasic Info-
Product Name:
Cynaroside
Other Name:LUTEOLIN-7-O-GLUCOSIDE 98+%;4H-1-Benzopyran-4-one, 2-(3,4-dihydroxyphenyl)-7-(.beta.-D-glucopyranosyloxy)-5-hydroxy-;luteolin7-o-glucopyranoside;luteoloside;CYNAROSIDE;LUTEOLIN-7-GLUCOSIDE;LUTEOLIN-7-O-GLUCOSIDE;LUTEOLIN-7-O-GLUCOSIDE WITH HPLC
CAS No.:5373-11-5
Molecular Formula:C21H20O11
InChIKeys:PEFNSGRTCBGNAN-QNDFHXLGSA-N
Molecular Weight:448.38
Exact Mass:448.38
EC Number:226-365-8
UNII:98J6XDS46I
Color/Form:Yellow to Very Dark Yellow
HScode:29389090
Categories:
Characteristics-
PSA:
186
XLogP3:0.5
Appearance:Solid
Density:1.713±0.06 g/cm3(Predicted)
Melting Point:256～258℃
Boiling Point:838.1±65.0 °C(Predicted)
Flash Point:296.8±27.8 °C
Refractive Index:1.740
Water Solubility:2888 mg/L @ 25 °C (est)
Storage Conditions:2-8°C
Critical Temperature & Pressure:Sealed in dry,2-8°C
Hazard IdentificationClassification of the substance or mixture
Not classified.
GHS label elements, including precautionary statements
Pictogram(s) No symbol. Signal word No signal word
Hazard statement(s) none
Precautionary statement(s) Prevention none
Response none
Storage none
Disposal none
Other hazards which do not result in classification
no data available
Handling and StoragePrecautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.
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Seller Information
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Business Type:
Manufactory
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Main Products:
Custom Synthetic Chemicals,Biological Stains,Pharmaceutical Intermediates,Cosmetic Grade Chemicals,Enzyme,Nucleosides
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Location:
Room 308-80, building 1, 1963 Huaguan Road, Tianhe District, Guangzhou
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Payment Terms:
TT against copy of documents,D/P,L/C,D/A,O/A,100% TT in advance
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Average lead Time:
30 days
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Total Annual Revenue:
$5 million-$10 million
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Total Employees:
51-100
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Year of Establishment:
2021
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Country Product Purchase Quantity Date Posted Post an enquiry for this product
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