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Home > Active Pharmaceutical Ingredients > Vitamins and Minerals Medicines > Cyanocobalamin Vitamin B12 used for eye drops
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Cyanocobalamin Vitamin B12 used for eye drops

Unit Price: Get Latest Price
CAS No.:

13115-03-2

Grade:

Food Grade; Healthcare Grade

Content:

97%

Port:

Dalian

Brand:

HANDOM CHEM

Packaging:

100g/Aluminum tin

Price valid (until):

2023-07-31

Company Type:
Manufactory
Location:
China
Qualification:
Main Products:

Semaglutide,Tirzepatide,HCG,Retatrutide,Cagrilintide,Medetomidine

  • Product Description

  • Seller Information

  • Description


      Product Detail  


    Product Name: Cyanocobalamin

    Alias: Vitamin B12; Vitamin B12 Cyanocobalamin

    CAS No.: 13115-03-2

    Molecular Formula: C63H88CoN14O14P-

    Molecular Weight: 1354.36



    Test ItemsSpecificationsTest Methods
    CharacteristicsDark red, crystalline powder or dark red crystalsPh. Eur. Monograph:0547Visual method
    Identification AUV: Absorption maxima at 278nm, 361nm and 547-559nm.Ph. Eur.Monograph/Ph.Eur.<2.2.25>
    A361nm/A278nm: 1.70~1.90A361nm/A547-559nm: 3.15~3.45

    Identification B

    UHPLC: The principal peak in the chromatogram obtained with the test solution is similar in retention time and size to the principal peak in the chromatogram obtained with reference solution(c).

    Ph. Eur.Monograph/Ph.Eur.<2.2.29>

    Loss on Drying≤10.0%Ph. Eur.Monograph/Ph.Eur.<2.2.32>
    Assay97.0%~102.0%Ph. Eur.Monograph/Ph.Eur.<2.2.25>
     




    Related Substances

    Total impurities≤3.0% 



    Ph. Eur.

    Monograph/Ph.Eur.<2.2.29>(UHPLC)

    7β, 8β-Lactone-cyanocobalamin≤0.7%
    50-Carboxycyanocobalamin≤0.5%
    34-Methylcyanocobalamin≤1.5%
    32-Carboxycyanocobalamin≤0.5%
    8-Epi-cyanocobalamin≤0.5%
    Impurity F≤0.5%
    Unspecified impurities≤0.2%
    Acetone≤5000ppmIn house/(GC)
    The total aerobic microbial count≤1000cfu/gChP 2020 <1105>
    The total combined yeasts/mould count≤100cfu/gChP 2020 <1105>

    Brief Introduction:
    Vitamin B12 is a general term for vitamin B group chemicals with a cobalt ring structure. There are four types of vitamin B12 family: cyanocobalamin, hydroxocobalamin, adenosylcobalamin and methylcobalamin, but clinically used vitamin B12 usually refers to cyanocobalamin.
    Cyanocobalamin and hydroxocobalamin have no direct biological activity. Cyanocobalamin is a prodrug, which can be converted into methylcobalamin and adenosylcobalamin in the human body. Methylcobalamin and adenosylcobalamin are the two active coenzyme forms of vitamin B12 in the human body.
    Cyanocobalamin and hydroxocobalamin are dark red crystals or crystalline powder; adenosylcobalamin is yellow-orange hexagonal crystals, which turn dark red when exposed to air; methylcobalamin is bright red needle-like crystals or crystalline powder.
    All four injections of cobalamin are red. In the storage of ordinary medicines, it is necessary to keep them away from sunlight. Cyanocobalamin is the most stable one, and generally it will not be degraded by sunlight; adenosylcobalamin and methylcobalamin are unstable when exposed to sunlight, and must be strictly protected from sunlight, and the injection time must also be shortened.
    The four cobalamins can prevent and treat red blood cell anemia and treat peripheral neuropathy. In the human body, we can only use adenosylcobalamin and methylcobalamin directly, cyanocobalamin and hydroxocobalamin need to be converted into adenosylcobalamin and methylcobalamin by the organelles in the liver before they can be utilized by the human body. For people with liver diseases, such as hepatitis and cirrhosis, adenosylcobalamin and methylcobalamin should be directly supplemented to reduce the burden on the liver, and patients with liver function impairment can be given priority.


    Packaging:
    100g/tin or 1kg/tin, the outer package is carton box.

    Storage Conditions:
    Preserved in unopened containers in a cool dry place before using; kept away from direct sunlight, heat and moisture.

    Shelf Life:
    60 months if stored under above conditions.

    Please enter the product introduction information...

    Basic Info
    Product Name:

    CYANOCOBALAMIN CO 57

    CAS No.:

    13115-03-2

  • Seller Information
    Business Type:

    Manufactory

    Main Products:

    Semaglutide,Tirzepatide,HCG,Retatrutide,Cagrilintide,Medetomidine

    Location:

    RM702, Building 21, Liuhe Road, Ganjingzi Dist, Dalian, Liaoning, China

    Payment Terms:

    TT against copy of documents,L/C,TT against B/L draft before shipment,100% TT in advance

    Average lead Time:

    15

    Total Annual Revenue:

    $5 million-$10 million

    Total Employees:

    51-100

    Year of Establishment:

    2020

    Dalian Handom Chemicals Co., Ltd.(HDC CHEM) is a professional 15-Year-Experienced Supplier of APIs & Intermediates, Pharmaceutical Excipients, Food & Nutraceutical Ingredients, Personal Care Chemicals and Specialty Chemicals from northeast of China, which strives to provide customers with high-quality products and comprehensive service across all over the world, our main products cover Retatrutide Lyophilized Powder, Retatrutide, Tirzepatide, Tirzepatide Lyophilized Powder, Semaglutide, Mazdutide, Cagrilintide, LL-37, Thymosin Alpha 1(Thymosin α1), MT-2, MOTS-c, HEP-1, TB-500, NAD+, GHK-Cu, Glow, Klow, Selank, Semax, Glutathione, 5-Amino-1MQ, ARA-290, SS-31, DSIP, SNAP-8, Medetomidine, Medetomidine Hydrochloride, Salcaprozate Sodium, Sodium 8-(2-hydroxybenzamido)octanoate, 2,6-Dimethyl Beta Cyclodextrin, mPEG-DMG-2K, mPEG-DSPE-2K, 1,2-Distearoyl-sn-3-phosphacholine(DSPC), 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine(DOPE), Pharmaceutical Grade Fructose, Lactose Anhydrous, Lactose Monohydrate, Orotic acid anhydrous, Orotic acid monohydrate, 6-Methyluracil, Chitosan, Mushroom Chitosan, Chitosan Hydrochloride, Chitosan Oligosaccharide, Alginate Oligosaccharide, Inulin, L-Serine, Mung Bean Peptide, Walnut Peptide, Rice Peptide, Oyster Peptide, Sea Cucumber Peptide, Hydrolyzed Keratin, Folic Acid, Vitamin E Acetate, Vitamin B2, Riboflavin Sodium Phosphate, Pyridoxal 5'-phosphate Monohydrate, Vegan Vitamin D3, Vitamin A Palmitate, Vitamin A Acetate, Apple Pectin, Citrus Pectin, Sunflower Pectin, Salidroside, Urolithin A, Milk Thistle Extract, Saffron Extract, Red Clover Extract, Sulforaphane, Glucoraphanin, Soy Isoflavones, Soy Lecithin, Soya Lecithin, Egg Yolk Lecithin, Phosphatidylserine, Cooling Agent WS-3, Cooling Agent WS-5, Cooling Agent WS-10, Cooling Agent WS-12, Cooling Agent WS-23, Cooling Agent WS-27, Menthyl Lactate, Menthyl PCA, Avobenzone, Benzophenone-3 (UV-9), Benzophenone-4 (UV-284), Bis-ethylhexyloxyphenol Methoxyphenyl Triazine (Bemotrizinol), Diethylaminohydroxybenzoyl Hexyl Benzoate (UVA Plus), Diethylhexyl Butamido Triazone (Iscotrizinol), Disodium Phenyl Dibenzimidazole Tetrasulfonate (DPDT), Ethylhexyl Triazone (UVT-150), Homosalate, Octocrylene, 2-Ethylhexyl Salicylate (Octyl Salicylate), 2-Ethylhexyl Trans-4-Methoxycinnamate (OMC), 2-Phenylbenzimidazole-5-Sulfonic Acid (UV-T), Lanolin Anhydrous, Palmitoyl Tripeptide-5, Dipeptide Diaminobutyroyl Benzylamide Diacetate, Biotinoyl Tripeptide-1, etc.

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