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China origin Nicotinamide 98.5%~101.5% USP41

Name: China origin Nicotinamide 98.5%~101.5% USP41
Brand: HANDOM CHEM
SKU: pr2305171661
Price: 3.7 USD
Availability: InStock

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CAS No.:

98-92-0

Grade:

Food Grade

Content:

98.5%

Port:

Shanghai, Beijing or Dalian

Brand:

HANDOM CHEM

Packaging:

1kg net Aluminum foil bag; 25kg net Carton or Cardboard Drum

Sample Available:

Yes

Price valid (until):

2023-07-31

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DALIAN HANDOM CHEMICALS CO.,LTD.

Company Type:

Manufactory

Location:

China

Payment Terms:

TT against copy of documents,L/C,TT against B/L draft before shipment,100% TT in advance

Average Lead Time:

15 days

Qualification:

Main Products:

Semaglutide,Tirzepatide,HCG,Retatrutide,Cagrilintide,Medetomidine

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Product Description
Seller Information
Inquiry History

Description

Product Detail

Product Name: Nicotinamide

Synonym: Niacinamide; VB3; Vitamin B3; Vitamin PP; 3-Pyridinecarboxamide

CAS No.: 98-92-0

Molecular Formula: C6H6N2O

Molecular Weight: 122.13

EINECS No.: 202-713-4

Brief Introduction:
Niacinamide, also known as nicotinamide, vitamin B3 or vitamin PP, is a water-soluble vitamin belonging to the B group vitamins. Nicotinic acid phosphate, NADP) components, the nicotinamide part of the two coenzyme structures in the human body has reversible hydrogenation and dehydrogenation properties, plays a role in hydrogen delivery in biological oxidation, can promote tissue respiration, biological oxidation Process and metabolism, important for maintaining the integrity of normal tissues, especially the skin, digestive tract and nervous system. When it is lacking, pellagra is caused due to the influence of cell respiration and metabolism, so this product is mainly used to prevent and treat pellagra, stomatitis, glossitis, etc.

Test Items		Specifications
Identification	Test A(IR)	The IR Absorption spectrum is concordant with the spectrum of reference standard.
Identification	Test B(UV)	Ratio: A245/A262, between 0.63 and 0.67
Melting Point	152°C~156°C
Assay(By HPLC)		Not less than 98.5%W/W and not more than 101.5%W/W of C6H6N2O, calculated on the anhydrous basis.
Appearance		White crystalline powder
Melting Range		128℃ ~ 131℃
Loss on Drying		Not more than 0.5%W/W
Residue on Ignition		Not more than 0.1%W/W
Heavy Metals		Not more than 0.003%
Readily Carbonizable Substances		Conforms to USP41
Organic Volatile Impurities		Conforms to USP41
Residual Solvents		Conforms to USP41

Applications:
♔ Vitamin drugs, which participate in the metabolic process in the body and are used to prevent and treat niacin deficiency such as pellagra;
♔ Niacinamide used in skin care products can prevent skin roughness, maintain skin cell health, and promote skin whitening. Used in hair care products to promote blood circulation in the scalp, healthy hair follicles, promote hair growth, and prevent baldness;
♔ Biochemical research; nutrient composition of tissue culture medium;
♔ Nicotinamide can also be used as a feed additive for animals, which can promote the growth of livestock and treat mucosal inflammation in animals.

Packagings:
1kg net Aluminum foil bag; 25kg net Carton or Cardboard Drum.

Storage Conditions:
Preserved in unopened original containers in a cool dry place before using; kept away from sunlight, heat and moisture.

Shelf Life:
36 months if stored under above conditions.

ECHEMI Editorial Reference

It is white needle crystal or crystalline powder, no smell or odor slightly, slightly bitter taste. The relative density is 1.4, melting point is 131-132 ℃.1 g of the above the product is soluble in 1 ml of water, 1.5 ml ethanol or 10 ml glycerin, insoluble in ether. The pH of 10% aqueous solution is 6.5-7.5. in dry air to light and heat stability, in alkaline or acidic solution, heating generation to nicotinic acid. Rats by oral LD502.5-3.5g/kg ADI value does not make special provisions (ECC,
Nicotinamide is a white powder. (NTP, 1992)|DryPowder; OtherSolid|Solid|WHITE CRYSTALLINE POWDER.
Nicotinamide is a white powder. (NTP, 1992)|Nicotinamide is a pyridinecarboxamide that is pyridine in which the hydrogen at position 3 is replaced by a carboxamide group. It has a role as an EC 2.4.2.30 (NAD(+) ADP-ribosyltransferase) inhibitor, a metabolite, a cofactor, an antioxidant, a neuroprotective agent, an EC 3.5.1.98 (histone deacetylase) inhibitor, an anti-inflammatory agent, a Sir2 inhibitor, a Saccharomyces cerevisiae metabolite, an Escherichia coli metabolite, a mouse metabolite, a human urinary metabolite and a geroprotector. It is a vitamin B3, a pyridinecarboxamide and a pyridine alkaloid. It derives from a nicotinic acid.|Mediatric is a DEA Schedule III controlled substance. Substances in the DEA Schedule III have a potential for abuse less than substances in Schedules I or II and abuse may lead to moderate or low physical dependence or high psychological dependence.|An important compound functioning as a component of the coenzyme NAD. Its primary significance is in the prevention and/or cure of blacktongue and pellagra. Most animals cannot manufacture this compound in amounts sufficient to prevent nutritional deficiency and it therefore must be supplemented through dietary intake.|Vitamin B refers to several water soluble vitamins often found together in foods, all of which are necessary for normal growth and metabolism, but none of which are synthesized in adequate amounts by humans. The common forms of vitamin B include vitamin B1 (thiamine), B2 (riboflavin), B3 (niacin), B6 (pyridoxine) and B12 (cyanocobalamin). Except for niacin (when given in high doses), there is no evidence that the other B vitamins, in physiologic or even super-physiologic high doses cause liver injury or jaundice. The major forms of vitamin B and selected other water soluble vitamins (biotin, pantothenic acid, choline) are discussed briefly in this record.|Niacinamide is the active form of vitamin B3 and a component of the coenzyme nicotinamide adenine dinucleotide (NAD). Niacinamide acts as a chemo- and radio-sensitizing agent by enhancing tumor blood flow, thereby reducing tumor hypoxia. This agent also inhibits poly(ADP-ribose) polymerases, enzymes involved in the rejoining of DNA strand breaks induced by radiation or chemotherapy.|An important compound functioning as a component of the coenzyme NAD. Its primary significance is in the prevention and/or cure of blacktongue and PELLAGRA. Most animals cannot manufacture this compound in amounts sufficient to prevent nutritional deficiency and it therefore must be supplemented through dietary intake.

Basic Info

Product Name:

Nicotinamide

Other Name:

3-Pyridinecarboxamide;Nicotinamide;Aminicotin;Benicot;Delonin Amide;Dipegyl;NAM;Niacinamide;Nicamindon;Nicofort;Nicotilamide;Nicotine acid amide;Nicotinic acid amide;Nicotinic amide;Nicotylamide;Niocinamide;Niozymin;Pelonin amide;3-Pyridinecarboxylic acid amide;Vi-Nicotyl;Vitamin B3 (niacinamide);Vitamin B;Nicosan 2;3-Carbamoylpyridine;Pelmine;β-Pyridinecarboxamide;Nicobion;Nicosylamide;Nicovit;Niavit PP;Nicovitina;Nicamina;Nicasir;3-(Aminocarbonyl)pyridine;m-(Aminocarbonyl)pyridine;3-Amidopyridine;Papulex;Nictoamide;Pelmin;NSC 13128;NSC 27452;Vitamin B3 (nicotinamide);123574-63-0;37321-14-5;78731-47-2

CAS No.:

98-92-0

Molecular Formula:

C6H6N2O

InChIKeys:

InChIKey=DFPAKSUCGFBDDF-UHFFFAOYSA-N

Molecular Weight:

122.12500

Exact Mass:

122.12

EC Number:

202-713-4

UNII:

25X51I8RD4

DEA Code Number:

1405

ICSC Number:

1703

NSC Number:

759115|27452|13128

DSSTox ID:

DTXSID2020929

NCI Thesaurus Code:

C2327

Color/Form:

White, powder, needles from benzene|Colorless crystalline solid|White, crystalline powder|Colorless needles

ATC Code:

A11HA01|A - Alimentary tract and metabolism

HScode:

2933399090

Categories:

Amides

Characteristics

PSA:

55.98000

XLogP3:

0.88080

Appearance:

Nicotinamide is a white powder. (NTP, 1992)

Density:

1.400 g/cm³ @ Temp: 25 °C

Melting Point:

130 °C

Boiling Point:

157 °C @ Press: 5 x 10^-4 Torr

Flash Point:

182°C

Refractive Index:

1.4660 (estimate)

Water Solubility:

1000 g/L (20 ºC)

Storage Conditions:

Keep container tightly closed in a dry and well-ventilated place. Keep in a dry place.

Vapor Pressure:

Vapour pressure, kPa at 35°C: 3.1

Vapor Density:

Relative vapour density (air = 1): 4.2

Toxicity:

LD50 s.c. in rats: 1.68 g/kg (Brazda, Coulson)

Odor:

Odorless

Taste:

Bitter taste

PH:

10% "wt in vol" solution in water is neutral to litmus

PKA:

3.35(at 20 °C)

Henrys Law Constant:

Henry's Law constant = 2.90X10-12 atm-cu m/mol at 25 °C (est)

Dissociation Constants:

3.35 (at 20 °C)|pKa = 3.35 (conjugate acid)|kb1 = 2.24X10-11; kb2 = 3.16X10-14

Collision Cross Section:

125.3 Å² [M+H]+ [CCS Type: DT, Method: single field calibrated with Agilent tune mix (Agilent)]|129.32 Å² [M+H]+ [CCS Type: DT, Method: stepped-field]|137.3 Å² [M+Na]+ [CCS Type: DT, Method: stepped-field]|118 Å² [M+H]+ [CCS Type: TW, Method: calibrated with polyalanine]|125.3 Å² [M+H]+ [CCS Type: DT, Method: single field calibrated with ESI Low Concentration Tuning Mix (Agilent)]|121.7 Å² [M+H]+ [CCS Type: TW, Method: calibrated with polyalanine and drug standards]|125.2 Å² [M+H]+ [CCS Type: DT, Method: single field calibrated]|126.7 Å² [M+H]+

Experimental Properties:

Readily hydrolyzed to free acid by heating in acid or alkaline solution|Forms crystalline salts with acids|Hydroxyl radical reaction rate constant = 2.34X10-12 cu cm/molec sec at 25 °C (est)

Air and Water Reactions:

Water soluble.

Reactive Group:

Amides and Imides

Reactivity Profile:

An amine and amide. Acts as a weak base in solution. Amines are chemical bases. They neutralize acids to form salts plus water. These acid-base reactions are exothermic. The amount of heat that is evolved per mole of amine in a neutralization is largely independent of the strength of the amine as a base. Amines may be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Flammable gaseous hydrogen is generated by amines in combination with strong reducing agents, such as hydrides. Organic amides/imides react with azo and diazo compounds to generate toxic gases. Flammable gases are formed by the reaction of organic amides/imides with strong reducing agents. Amides are very weak bases (weaker than water). Imides are less basic yet and in fact react with strong bases to form salts. That is, they can react as acids. Mixing amides with dehydrating agents such as P2O5 or SOCl2 generates the corresponding nitrile. The combustion of these compounds generates mixed oxides of nitrogen (NOx).

Autoignition Temperature:

480 °C

Physical Dangers:

Dust explosion possible if in powder or granular form, mixed with air.

See More Nicotinamide Properties 

Hazard Identification

Classification of the substance or mixture

Eye irritation, Category 2

GHS label elements, including precautionary statements

Precautionary statement(s)
Pictogram(s)
Signal word	Warning
Hazard statement(s)	H319 Causes serious eye irritation
Prevention	P264 Wash ... thoroughly after handling. P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...
Response	P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
Storage	none
Disposal	none

Other hazards which do not result in classification

no data available

Handling and Storage

Precautions for safe handling

Prevent deposition of dust. Closed system, dust explosion-proof electrical equipment and lighting. Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

Conditions for safe storage, including any incompatibilities

Separated from oxidants.

See More Nicotinamide Safety Data Sheet 

Seller Information

Business Type:
Manufactory

Main Products:
Semaglutide,Tirzepatide,HCG,Retatrutide,Cagrilintide,Medetomidine

Location:
RM702, Building 21, Liuhe Road, Ganjingzi Dist, Dalian, Liaoning, China

Payment Terms:
TT against copy of documents,L/C,TT against B/L draft before shipment,100% TT in advance

Average lead Time:
15 days

Total Annual Revenue:
$5 million-$10 million

Total Employees:
51-100

Year of Establishment:
2020

Dalian Handom Chemicals Co., Ltd.(HDC CHEM) is a professional 15-Year-Experienced Supplier of APIs & Intermediates, Pharmaceutical Excipients, Food & Nutraceutical Ingredients, Personal Care Chemicals and Specialty Chemicals from northeast of China, which strives to provide customers with high-quality products and comprehensive service across all over the world, our main products cover Retatrutide Lyophilized Powder, Retatrutide, Tirzepatide, Tirzepatide Lyophilized Powder, Semaglutide, Mazdutide, Cagrilintide, LL-37, Thymosin Alpha 1(Thymosin α1), MT-2, MOTS-c, HEP-1, TB-500, NAD+, GHK-Cu, Glow, Klow, Selank, Semax, Glutathione, 5-Amino-1MQ, ARA-290, SS-31, DSIP, SNAP-8, Medetomidine, Medetomidine Hydrochloride, Salcaprozate Sodium, Sodium 8-(2-hydroxybenzamido)octanoate, 2,6-Dimethyl Beta Cyclodextrin, mPEG-DMG-2K, mPEG-DSPE-2K, 1,2-Distearoyl-sn-3-phosphacholine(DSPC), 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine(DOPE), Pharmaceutical Grade Fructose, Lactose Anhydrous, Lactose Monohydrate, Orotic acid anhydrous, Orotic acid monohydrate, 6-Methyluracil, Chitosan, Mushroom Chitosan, Chitosan Hydrochloride, Chitosan Oligosaccharide, Alginate Oligosaccharide, Inulin, L-Serine, Mung Bean Peptide, Walnut Peptide, Rice Peptide, Oyster Peptide, Sea Cucumber Peptide, Hydrolyzed Keratin, Folic Acid, Vitamin E Acetate, Vitamin B2, Riboflavin Sodium Phosphate, Pyridoxal 5'-phosphate Monohydrate, Vegan Vitamin D3, Vitamin A Palmitate, Vitamin A Acetate, Apple Pectin, Citrus Pectin, Sunflower Pectin, Salidroside, Urolithin A, Milk Thistle Extract, Saffron Extract, Red Clover Extract, Sulforaphane, Glucoraphanin, Soy Isoflavones, Soy Lecithin, Soya Lecithin, Egg Yolk Lecithin, Phosphatidylserine, Cooling Agent WS-3, Cooling Agent WS-5, Cooling Agent WS-10, Cooling Agent WS-12, Cooling Agent WS-23, Cooling Agent WS-27, Menthyl Lactate, Menthyl PCA, Avobenzone, Benzophenone-3 (UV-9), Benzophenone-4 (UV-284), Bis-ethylhexyloxyphenol Methoxyphenyl Triazine (Bemotrizinol), Diethylaminohydroxybenzoyl Hexyl Benzoate (UVA Plus), Diethylhexyl Butamido Triazone (Iscotrizinol), Disodium Phenyl Dibenzimidazole Tetrasulfonate (DPDT), Ethylhexyl Triazone (UVT-150), Homosalate, Octocrylene, 2-Ethylhexyl Salicylate (Octyl Salicylate), 2-Ethylhexyl Trans-4-Methoxycinnamate (OMC), 2-Phenylbenzimidazole-5-Sulfonic Acid (UV-T), Lanolin Anhydrous, Palmitoyl Tripeptide-5, Dipeptide Diaminobutyroyl Benzylamide Diacetate, Biotinoyl Tripeptide-1, etc.

Inquiry History

108 Inquiries

Country	Product	Purchase Quantity	Date Posted
India	Nicotinamide	45.00 KG	Jun 13, 2025
India	Nicotinamide	25.00 KG	Jun 12, 2025
India	Nicotinamide	50.00 KG	Jun 11, 2025
India	Nicotinamide	50.00 KG	Jun 13, 2025
United States	Niacinamide	1 KG	Feb 5, 2024
India	Nicotinamide	25.00 KG	Jun 11, 2025
Egypt	Niacinamide	1.00 KG	Aug 28, 2026
Russia	Niacinamide	1 KG	Dec 2, 2024
India	Niacinamide	100.00 KG	Aug 3, 2026
Pakistan	Niacinamide	5.00 KG	Sep 14, 2026
India	Nicotinamide	5000 G	Oct 6, 2026
India	Niacinamide	200.00 KG	Sep 2, 2026
India	Niacinamide	1.00 KG	Aug 22, 2026
Nigeria	Niacinamide	100.00 KG	Aug 20, 2026
Uganda	Niacinamide	500 G	Aug 13, 2026
Pakistan	Niacinamide	10.00 MT	Jul 10, 2026
India	Nicotinamide	1 KG	Jul 1, 2026
South Korea	Niacinamide	150 KG	Jun 29, 2026
India	Niacinamide	1.00 MT	Jun 26, 2026
Nigeria	Niacinamide	100.00 KG	Jun 22, 2026

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China origin Nicotinamide 98.5%~101.5% USP41

Product Description

Seller Information

Inquiry History

Classification of the substance or mixture

GHS label elements, including precautionary statements

Other hazards which do not result in classification

Precautions for safe handling

Conditions for safe storage, including any incompatibilities

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