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Home > Food Additives > Nutrition Supplements > Orotic acid for Sale > China Largest Manufacturer factory Supply Orotic Acid 99.9% white powder from China largest Manufacturer factory Grade TOP AAAAA Brand Leader
China Largest Manufacturer factory Supply Orotic Acid 99.9% white powder from China largest Manufacturer factory Grade TOP AAAAA Brand Leader buy - large image1
China Largest Manufacturer factory Supply Orotic Acid 99.9% white powder from China largest Manufacturer factory Grade TOP AAAAA Brand Leader buy - image1
China Largest Manufacturer factory Supply Orotic Acid 99.9% white powder from China largest Manufacturer factory Grade TOP AAAAA Brand Leader buy - image2
China Largest Manufacturer factory Supply Orotic Acid 99.9% white powder from China largest Manufacturer factory Grade TOP AAAAA Brand Leader buy - image3
China Largest Manufacturer factory Supply Orotic Acid 99.9% white powder from China largest Manufacturer factory Grade TOP AAAAA Brand Leader buy - image4
China Largest Manufacturer factory Supply Orotic Acid 99.9% white powder from China largest Manufacturer factory Grade TOP AAAAA Brand Leader buy - image5
China Largest Manufacturer factory Supply Orotic Acid 99.9% white powder from China largest Manufacturer factory Grade TOP AAAAA Brand Leader buy - image6

China Largest Manufacturer factory Supply Orotic Acid 99.9% white powder from China largest Manufacturer factory Grade TOP AAAAA Brand Leader

GMP HALAL KOSHER ISO FDA 7 Inquiries

Unit Price:

$1/KG EXW

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CAS No.:

65-86-1

Grade:

99%

Content:

99.9%

Port:

China Ports

Brand:

Brand Leader

Packaging:

25Kg/drum

Price valid (until):

2029-12-30

Company Type:
Manufactory
Location:
China
Qualification:
Main Products:

Biochemicals Ingredients,Vitamin Amino Acid Ingredients,Cosmestic Ingredients,Pharma Chemicals,Organic Fine Chemicals,Food Nutrient Ingredients

  • Product Description

  • Seller Information

  • Inquiry History

  • Description
    Orotic acid Chemical Properties
    Melting point  ≥300 °C
    Boiling point  280.29°C (rough estimate)
    density  1.6814 (rough estimate)
    refractive index  1.4800 (estimate)
    storage temp.  Sealed in dry,Room Temperature
    solubility  DMSO : 32 mg/mL (205.00 mM; Need ultrasonic and warming)
    pka pK1:1.8(+1);pK2:9.55(0) (25°C)
    form  Crystalline Powder
    color  White
    Water Solubility  Slightly soluble
    Merck  13,6942
    BRN  383901
    Stability: Stable. Incompatible with strong oxidizing agents.
    InChIKey PXQPEWDEAKTCGB-UHFFFAOYSA-N
    LogP -0.830
    CAS DataBase Reference 65-86-1(CAS DataBase Reference)
    NIST Chemistry Reference Orotic acid(65-86-1)
    EPA Substance Registry System Orotic acid (65-86-1)

    Safety Information
    Hazard Codes  Xn,Xi
    Risk Statements  22-36/37/38
    Safety Statements  26-36/37/39-22-37/39
    WGK Germany  3
    RTECS  RM3180000
    10-21
    Hazard Note  Harmful
    TSCA  Yes
    HS Code  29335990
    Hazardous Substances Data 65-86-1(Hazardous Substances Data)
    Toxicity pic-esc 1 g/L ZAPOAK12,583,72

    Certificates

    Basic Info
    Product Name:

    Orotic acid

    Other Name:

    4-Pyrimidinecarboxylic acid,1,2,3,6-tetrahydro-2,6-dioxo-;Orotic acid;1,2,3,6-Tetrahydro-2,6-dioxo-4-pyrimidinecarboxylic acid;Animal galactose factor;6-Carboxyuracil;6-Uracilcarboxylic acid;Whey factor;2,6-Dihydroxy-4-pyrimidinecarboxylic acid;Oroturic;Orotyl;Orodin;Orotonin;2,6-Dioxo-1,2,3,6-tetrahydropyrimidine-4-carboxylic acid;NSC 79560;NSC 9791;Vitamin B13;2,4-Dihydroxypyrimidine-6-carboxylic acid;2,4-Dioxo-1H-pyrimidine-6-carboxylic acid;2-Hydroxy-6-oxo-1,6-dihydropyrimidine-4-carboxylic acid;6784-70-9;58915-47-2

    CAS No.:

    65-86-1

    Molecular Formula:

    C5H4N2O4

    InChIKeys:

    InChIKey=PXQPEWDEAKTCGB-UHFFFAOYSA-N

    Molecular Weight:

    156.09600

    Exact Mass:

    156.10

    EC Number:

    200-619-8

    UNII:

    61H4T033E5

    NSC Number:

    758903|9791

    DSSTox ID:

    DTXSID0025814

    Color/Form:

    Crystals

    HScode:

    29335990

    Categories:

    Nutrition Supplements

    Characteristics
    PSA:

    103.02000

    XLogP3:

    -1.4

    Appearance:

    Orotic acid appears as white crystals or crystalline powder. (NTP, 1992)

    Density:

    1.642 g/cm3

    Melting Point:

    345-346 °C

    Boiling Point:

    656.9ºC at 760 mmHg

    Flash Point:

    351.1ºC

    Refractive Index:

    1.705

    Water Solubility:

    H2O: Slightly soluble

    Storage Conditions:

    Keep in a cool, dry, dark location in a tightly sealed container or cylinder. Keep away from incompatible materials, ignition so

    Vapor Pressure:

    1X10-8 mm Hg at 25 deg C (est)

    Toxicity:

    pic-esc 1 g/L ZAPOAK12,583,72

    Henrys Law Constant:

    Henry's Law constant = 8.1X10-15 atm-cu m/mol at 25 °C (est)

    Dissociation Constants:

    pKa1 = 2.07; pKa2 = 9.45

    Collision Cross Section:

    138.85 Ų [M+H]+ [CCS Type: DT, Method: stepped-field]|181.87 Ų [M+Na]+ [CCS Type: DT, Method: stepped-field]|125.2 Ų [M-H]- [CCS Type: DT, Method: stepped-field]|121.7 Ų [M-H]-

    Experimental Properties:

    Hydroxyl radical reaction rate constant = 8.9X10-12 cu cm/molec-sec at 25 °C (est)

    Air and Water Reactions:

    Slightly soluble in water.

    Reactive Group:

    Acids, Carboxylic

    Reactivity Profile:

    Carboxylic acids, such as OROTIC ACID, donate hydrogen ions if a base is present to accept them. They react in this way with all bases, both organic (for example, the amines) and inorganic. Their reactions with bases, called "neutralizations", are accompanied by the evolution of substantial amounts of heat. Neutralization between an acid and a base produces water plus a salt. Carboxylic acids with six or fewer carbon atoms are freely or moderately soluble in water; those with more than six carbons are slightly soluble in water. Soluble carboxylic acid dissociate to an extent in water to yield hydrogen ions. The pH of solutions of carboxylic acids is therefore less than 7.0. Many insoluble carboxylic acids react rapidly with aqueous solutions containing a chemical base and dissolve as the neutralization generates a soluble salt. Carboxylic acids in aqueous solution and liquid or molten carboxylic acids can react with active metals to form gaseous hydrogen and a metal salt. Such reactions occur in principle for solid carboxylic acids as well, but are slow if the solid acid remains dry. Even "insoluble" carboxylic acids may absorb enough water from the air and dissolve sufficiently in it to corrode or dissolve iron, steel, and aluminum parts and containers. Carboxylic acids, like other acids, react with cyanide salts to generate gaseous hydrogen cyanide. The reaction is slower for dry, solid carboxylic acids. Insoluble carboxylic acids react with solutions of cyanides to cause the release of gaseous hydrogen cyanide. Flammable and/or toxic gases and heat are generated by the reaction of carboxylic acids with diazo compounds, dithiocarbamates, isocyanates, mercaptans, nitrides, and sulfides. Carboxylic acids, especially in aqueous solution, also react with sulfites, nitrites, thiosulfates (to give H2S and SO3), dithionites (SO2), to generate flammable and/or toxic gases and heat. Their reaction with carbonates and bicarbonates generates a harmless gas (carbon dioxide) but still heat. Like other organic compounds, carboxylic acids can be oxidized by strong oxidizing agents and reduced by strong reducing agents. These reactions generate heat. A wide variety of products is possible. Like other acids, carboxylic acids may initiate polymerization reactions; like other acids, they often catalyze (increase the rate of) chemical reactions.

    Hazard Identification

    Classification of the substance or mixture

    Acute toxicity - Category 4, Oral

    Skin irritation, Category 2

    Eye irritation, Category 2

    Specific target organ toxicity – single exposure, Category 3

    GHS label elements, including precautionary statements

    Pictogram(s)
    Signal word

    Warning

    Hazard statement(s)

    H302 Harmful if swallowed

    H315 Causes skin irritation

    H319 Causes serious eye irritation

    H335 May cause respiratory irritation

    Precautionary statement(s)
    Prevention

    P264 Wash ... thoroughly after handling.

    P270 Do not eat, drink or smoke when using this product.

    P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...

    P261 Avoid breathing dust/fume/gas/mist/vapours/spray.

    P271 Use only outdoors or in a well-ventilated area.

    Response

    P301+P317 IF SWALLOWED: Get medical help.

    P330 Rinse mouth.

    P302+P352 IF ON SKIN: Wash with plenty of water/...

    P321 Specific treatment (see ... on this label).

    P332+P317 If skin irritation occurs: Get medical help.

    P362+P364 Take off contaminated clothing and wash it before reuse.

    P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

    P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing.

    P319 Get medical help if you feel unwell.

    Storage

    P403+P233 Store in a well-ventilated place. Keep container tightly closed.

    P405 Store locked up.

    Disposal

    P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.

    Other hazards which do not result in classification

    no data available

    Handling and Storage

    Precautions for safe handling

    Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

    Conditions for safe storage, including any incompatibilities

    Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

  • Seller Information
    Business Type:

    Manufactory

    Main Products:

    Biochemicals Ingredients,Vitamin Amino Acid Ingredients,Cosmestic Ingredients,Pharma Chemicals,Organic Fine Chemicals,Food Nutrient Ingredients

    Location:

    National Aerospace Economic & Technical Development Zone,Chang'an,Xi'an,China

    Payment Terms:

    TT against copy of documents,D/P,L/C,D/A,O/A,TT against B/L draft before shipment,100% TT in advance

    Average lead Time:

    5

    Total Annual Revenue:

    $10 million-$25 million

    Total Employees:

    Above 1000

    Year of Establishment:

    2014

    Certifications:

    Level A of Tax Credit Registration Assessment by Government,Good Product Quality Management Certificate of Shanxi Province,China,Company Trade Union Qualification Certificate,Excellent Group Enterprise of Quality and credit in Shaanxi ProvinceChina,AAA TOP Credit Excellent Group Enterprise of Shanxi Province,China,FDA


    24 Hours Team Service

    Email

    info@leader-biogroup.com   

    Hot Line

    +86-029-68895030  

    +86-029-68569961  

    +86-029-68569962  

    Fax

    +86-029-68895030


    Leader Biochemical Group is a large leader incorporated industry manufacturers and suppliers of advanced refined raw materials From the year of 1996 when our factory was put into production to year of 2020, our group has successively invested in more than 52 factories Base with shares and subordinates.We focus on manufacture Pharm & chemicals, functional active ingredients, nutritional Ingredients, health care products, cosmetics, pharmaceutical and refined feed, oil, natural plant ingredients industries to provide top quality of GMP standards products.All the invested factories' product lines cover API and intermediates, vitamins, amino acids, plant extracts, daily chemical products, cosmetics raw materials, nutrition and health care products, food additives, feed additives, essential oil products, fine chemical products and agricultural chemical raw materials And flavors and fragrances. Especially in the field of vitamins, amino acids, pharmaceutical raw materials and cosmetic raw materials, we have more than 20 years of production and sales experience. All products meet the requirements of high international export standards and have been recognized by customers all over the world.

    • Our manufacture basement & R&D center located in National Aerospace Economic & Technical Development Zone Xi`an Shaanxi China. Now not only relying on self-cultivation and development as well as maintains good cooperative relations with many famous research institutes and universities in China. Now, we have closely cooperation with Shanghai Institute of Organic Chemistry of Chinese Academy of Science, Beijing Institute of Material Medical of Chinese Academy of Medical Science, China Pharmaceutical University, Zhejiang University. Closely cooperation with them not only integrating Science and technology resources, but also increasing the R&D speed and improving our R&D power. Offering Powerful Tech supporting Platform for group development. Keep serve the manufacture and the market as the R&D central task, focus on the technical research.

      Now there are 3 technology R & D platforms including biological extract, microorganism fermentation and chemical synthesis, and can independently research and develop kinds of difficult APIs and pharmaceutical intermediates. With the strong support of China State Institute of Pharmaceutical Industry (hereinafter short for CSIPI), earlier known as Shanghai Institute of Pharmaceutical Industry (SIPI), we have unique advantages in the R & D and industrialization of high-grade, precision and advanced products.

      Now our Group technical force is abundant, existing staff more that 1000 people, senior professional and technical staff accounted for more than 50% of the total number of employees, including 15 PhD research and development personnel, 5 master′ S degree in technical and management personnel 9 people. We have advanced equipment like fermentation equipment and technology also extraction, isolation, purification, synthesis with rich production experience and strict quality control system, According to the GMP required, quickly transforming the R&D results to industrial production in time, it is our advantages and our products are exported to North and South America, Europe, Middle East, Africa, and other five continents and scale the forefront in the nation, won good international reputation.

      We believe only good quality can bring good cooperation, quality is our key spirit during our production, we are warmly welcome clients and partner from all over the world contact us for everlasting cooperation, Leader will be your strong, sincere and reliable partner in China.

    • Process Capability :   It has more than 100 sets of multi-functional reaction reactors, such as 100l~6300l enamel, stainless steel, Hastelloy, etc. It can realize Grignard, coupling, bromination, Wittig reaction and other conventional reactions. There are microchannel reactor workshops, which can realize continuous production, energy conservation and emission reduction. It can realize high pressure, high vacuum rectification, ultra-low temperature (-80 ℃ ~-100 ℃), ultra-high temperature (300 ℃ ~400 ℃) and other special reactions. It can realize the customization and processing of customers' products.

                                      

        Factory Overview

                                                                                 Factory Production Lines

    Our Professional Lab

                               Factory Warehouse 

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    GROUP HONOR

    Honor Name: Level A of Tax Credit Registration Assessment   
    Issued By:National Administration of Taxation & Shaanxi Tax Bureau   
    Authorised Date:2018-09-16  
    Description: National Administration of Taxation & Shaanxi Tax Bureau




    Honor Name: AAA TOP Credit Excellent Group Enterprise of Shanxi Province,China  
    Issued By:China Association of Shaanxi product Quality management Center   
    Authorised Date:2018-12-31  
    Description:AAA TOP Credit Excellent Group Enterprise of Shanxi Province,China



    Honor Name:Excellent Group Enterprise of Quality and credit in Shaanxi ProvinceChina

    Issued By: China Association of Shaanxi product Quality management Center

    Authorised Date:2018-12-31

    Description: Excellent Group Enterprise of Quality and Integrity in Shaanxi Province,China



    Honor Name: Products Patent Certificates


  • Inquiry History
    7 Inquiries
    Country Product Purchase Quantity Date Posted
    India

    Orotic acid

    3 MT Jul 22, 2025
    United Kingdom

    Orotic acid 99%

    25 KG Oct 12, 2023
    Romania

    orotic acid crude

    50 MT Dec 11, 2025
    India

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    1.00 20' Fcl Oct 26, 2023
    India

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