GRF (1-29) amide 98% white powder G-1303 cellmano
516482-86-3
Chemical Grade
98%
shanghai
cellmano
1g/vial
2029-12-31
Cagrilintide,SS-31, Elamipretide,Semaglutide,Tirzepatide,Retatrutide
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Product Description
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Seller Information
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DescriptionBasic Info
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Product Name:
Sermorelin Acetate
Other Name:1-29-Somatoliberin (human pancreatic islet), 29-L-argininamide-,acetate
CAS No.:516482-86-3
Molecular Formula:C151H250N44O44S
Molecular Weight:3417.99
Categories:
Characteristics-
Water Solubility:
Water: 1 mg/ml
Critical Temperature & Pressure:-20°C
Research-
Class:
GHRH analog (1–29 amino-terminal fragment, 29-amino-acid peptide amide)
Status:FDA-approved diagnostic agent (Geref, discontinued). NOT for therapeutic use.
Mechanism:A synthetic 29-amino-acid peptide (H-Tyr-Ala-Asp-Ala-Ile-Phe-Thr-Asn-Ser-Tyr-Arg-Lys-Val-Leu-Gly-Gln-Leu-Ser-Ala-Arg-Lys-Leu-Leu-Gln-Asp-Ile-Met-Ser-Arg-NH₂) identical to the amino-terminal segment of endogenous human GHRH. Sermorelin binds to the GHRH receptor (GHRHR) on anterior pituitary somatotrophs, stimulating pulsatile GH synthesis and secretion via the cAMP/PKA pathway. Unlike exogenous GH, sermorelin preserves the endogenous GH pulsatility and IGF-1 feedback loop.
EC50 (Ghrhr Ec50):~0.1–1 nM (cAMP accumulation in rat pituitary cells)
Source:DrugBank: DB00010. Frohman LA, et al. Endocr Rev. 1986;7(3):223–253.DOI
Clinical Development:FDA:Geref (approved 1991-10-11)
References-
ChEMBL:
CHEMBL1201555
DrugBank:KEGG DRUG:D08554
PubChem:Literature:Disclaimer:Sermorelin was FDA-approved as a diagnostic agent (Geref) for growth hormone deficiency but has been discontinued (not for safety reasons). It is NOT approved for anti-aging, bodybuilding, or therapeutic GH replacement. This listing is for industrial and laboratory research use only. Research-chemical listings on B2B marketplaces are not interchangeable with approved medicines. It is not medical advice, a clinical recommendation, or an approved therapy description. Always verify regulatory status, purity, and intended use with the supplier and applicable authorities before purchase or use.
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Seller Information
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Business Type:
Trader
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Main Products:
Cagrilintide,SS-31, Elamipretide,Semaglutide,Tirzepatide,Retatrutide
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Location:
Room C608, Chiyuan venture park
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Payment Terms:
TT against copy of documents,100% TT in advance
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Average lead Time:
10 days
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Total Annual Revenue:
$5 million-$10 million
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Total Employees:
11-50
Cellmano Biotech Limited focus on researching and developing solid phase peptide synthesis methodology since 2011. Cellmano has 10 years experience in researching, developing and manufacturing peptides by solid peptide phase synthesis.
Cellmano not only provides cosmeceuticals peptide & generic peptides to the customers, but also offer peptide CMO service and custom peptides synthesis service depend on the requirement from the customers over the world. Cellmano has state-of-the-art labs armed with excellent instrument for synthesis, purify and analysis .Cellmao control the quality by checking the materials, supervising produce process and finally QC. Cellmano keep all the synthesis records , purify methods and analysis result for every batch peptide product with staff and time invovled in the archives. Synthesizing by classical solid phase mothed invented by Prof.Bruce Merrified and purifying by HPLC instrument, Cellmano supply the customers excellent peptide products with reasonable price ,while maintain high quality, to help the customers to cut down their cost and shorten the time . Cellmano is trying her best to complement the inventory for more than 2000 popular peptide products, to make sure the customers can get what they need in one week from Cellmano’s inventory. Also to saitisfy diverse request from different customers for different projects, Cellmano provide custom synthesis for peptides from mgs to kgs with the purity from crude to 98% .
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