 Home > Biochemical Engineering > Amino Acids and Derivatives > Adenosine, 5′-[[(3S)-3-amino-3-carboxypropyl]methylsulfonio]-5′-deoxy-, sulfate, 4-methylbenzenesulfonate sulfate (1:1:1:1) for Sale > S-Adenosyl-L-Methionine Disulfate Tosylate 95.0% White to off-white powder HDC-SAM-T HANDOM CHEM

S-Adenosyl-L-Methionine Disulfate Tosylate 95.0% White to off-white powder HDC-SAM-T HANDOM CHEM

Name: S-Adenosyl-L-Methionine Disulfate Tosylate 95.0% White to off-white powder HDC-SAM-T HANDOM CHEM
Brand: HANDOM CHEM
SKU: pr2306291418
Price: 160 USD
Availability: InStock

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CAS No.:

97540-22-2

Grade:

Pharmaceutical Grade

Content:

95%

Port:

Dalian, Beijing or Shanghai

Brand:

HANDOM CHEM

Packaging:

100g/Aluminum foil bag, 1kg/Aluminum foil bag, 25kg/drum

Price valid (until):

2023-08-31

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DALIAN HANDOM CHEMICALS CO.,LTD.

Company Type:

Manufactory

Location:

China

Qualification:

Main Products:

Semaglutide,Tirzepatide,HCG,Retatrutide,Cagrilintide,Medetomidine

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Product Description
Seller Information

Description

Product Details

Product Name: S-Adenosyl-L-Methionine Disulfate Tosylate

Alias: 4-methylbenzenesulfonate; AdeMethionine Disulfate Tosylate; Ademetionine Disulfate Tosylate; hydrogen sulfate; S-adenisyl-L-Methioninedisulfate-p-toluenesulfonate; S-Adenosyl-5-L-Methionine Tosylate; S-Adenosyl-L-Methionine disulfate tosylate(SAM-T); SAM-T; SAM-T(S-Adenosyl-5-L-Methionine Tosylate)

CAS No.: 97540-22-2

EINECS No.: 249-946-8

Molecular Formula: C22H34N6O16S4

Molecular Weight: 766.78

Brief Introduction:
S-Adenosyl-L-methionine Disulfate Tosylate, referred to as: SAM-T, is a natural molecule that exists in all cells of the human body. Concentrations are higher in the liver, adrenal gland and pineal gland, and evenly distributed in the brain.

S-Adenosyl-L-methionine Disulfate Tosylate has multiple protective effects on liver cells through mechanisms such as anti-oxidative free radicals and promotion of liver cell regeneration.

In recent years, studies have also found that S-Adenosyl-L-methionine Disulfate Tosylate can increase the fluidity of neuronal membranes in the brain of patients, promote the production of excitatory neurotransmitters, has an important dual role in improving the mood of liver disease patients and treating depression.

The concentration of SAM-T in the cerebrospinal fluid of patients can be increased by intravenous or oral medication. Adjuvant therapy for patients with mild to moderate depression is safer and more effective, bringing a broader space for the treatment of human "physiological-psychological" diseases.

Test Items		Specifications
Appearance		White to off-white powder
Identification	Infrared	Conforms to the Reference Spectrum
Identification	HPLC	The retention time of the major peak corresponds to the reference sample
Water Content(K. F)		Not more than 3.0%
Sulphated Ash		Not more than 0.5%
pH Value(5% Aqueous Solution)		1.0 ~ 2.0
S,S-Isomer(HPLC)		Not less than 75.0%
SAM-e ION(HPLC)		49.5% ~ 54.7%
P-Toluenesulfonic Acid		21.0% ~ 24.0%
Content of Sulfate(SO4) (HPLC)		23.5% ~ 26.5%
S-Adenosyl-L-methionine Disulfate Tosylate		95.0% ~ 103.0%
Related Substances(HPLC)	S-Adenosyl-L-Homocysteine	Not more than 1.0%
	Adenine	Not more than 1.0%
	Methylthioadenosine	Not more than 1.5%
	Adenosine	Not more than 1.0%
	Single Unknown Impurities	Not more than 1.0%
	Total Impurities	Not more than 3.5%
Heavy Metals		Not more than 10ppm
Lead(Pb)		Not more than 3ppm
Cadmium(Cd)		Not more than 1ppm
Arsenic(As)		Not more than 1ppm
Mercury(Hg)		Not more than 0.1ppm
Microbiology	Total Plate Count	Not more than 1000CFU/g
	Yeasts & Moulds	Not more than 100CFU/g
	Escherichia coli/10g	Negative
	Salmonella/10g	Negative
	Staphylococcus aureus/10g	Negative

Product Use and Impact on The Human Body:

1. Good Liver Nutrition：
S-Adenosyl-L-methionine Disulfate Tosylate has a protective effect on liver function in patients with liver cancer after TACE treatment, and the short-term effect of protecting acute liver injury is satisfactory.

2. Regulate Emotions, Antidepressant：
S-Adenosyl-L-methionine Disulfate Tosylate is a natural substance widely present in the body, and it participates in many important biological processes as a methyl donor. It has been found to have metabolic abnormalities in several psychiatric disorders, such as schizophrenia and affective disorders.
Medicinal grade S-Adenosyl-L-methionine Disulfate Tosylate is a potent antidepressant. It has the characteristics of definite curative effect, quick onset, small adverse reactions, and patients' willingness to accept it. Especially suitable for patients with chronic liver disease or poor physical condition and elderly patients.

3. Improve Joint Pain:
S-Adenosyl-L-methionine Disulfate Tosylate has anti-inflammation, relieves pain, promotes cartilage tissue formation and injury healing, maintains bone and joint health, and has a significant effect on various arthritis and joint injuries.

4. Improve Sleep

5. Adjuvant treatment of Parkinson's disease, pancreatitis, Alzheimer's disease, etc.

Packaging:
100g/Aluminum foil bag, 1kg/Aluminum foil bag, 25kg/drum or according to the specific requirements from customers.

Storage Conditions:
Preserved in unopened original containers in a cool dry place before using; kept away from sunlight, heat and moisture.

Shelf Life:
24 months if stored under above conditions.

Basic Info

Product Name:

Adenosine, 5′-[[(3S)-3-amino-3-carboxypropyl]methylsulfonio]-5′-deoxy-, sulfate, 4-methylbenzenesulfonate sulfate (1:1:1:1)

Other Name:

Adenosine,5′-[[(3S)-3-amino-3-carboxypropyl]methylsulfonio]-5′-deoxy-,sulfate,4-methylbenzenesulfonate sulfate (1:1:1:1);Adenosine,5′-[(3-amino-3-carboxypropyl)methylsulfonio]-5′-deoxy-,(3S)-,sulfate (salt),4-methylbenzenesulfonate (salt) sulfate (salt) (1:1:1:1);Adenosine,5′-[[(3S)-3-amino-3-carboxypropyl]methylsulfonio]-5′-deoxy-,sulfate (salt),4-methylbenzenesulfonate (salt) sulfate (salt) (1:1:1:1);FO 1561;S-Adenosyl-L-methionine disulfate tosylate;110899-33-7;113883-52-6;137088-54-1;89365-51-5

CAS No.:

97540-22-2

Molecular Formula:

C15H23N6O5S.C7H8O3S.H2O4S.HO4S

InChIKeys:

InChIKey=XDCFCHNAIMYBAZ-XQVUROGGSA-N

Molecular Weight:

766.8

Exact Mass:

766.091431

UNII:

R96GHU97Q3|4G5PYL0DR1|564ROC9U09

NCI Thesaurus Code:

C71745

HScode:

2934999090

Categories:

Amino Acids and Derivatives

Characteristics

PSA:

415

XLogP3:

1.20310

Appearance:

white powder

See More Adenosine, 5′-[[(3S)-3-amino-3-carboxypropyl]methylsulfonio]-5′-deoxy-, sulfate, 4-methylbenzenesulfonate sulfate (1:1:1:1) Properties 

Hazard Identification

Classification of the substance or mixture

Skin corrosion, Sub-category 1B

Serious eye damage, Category 1

GHS label elements, including precautionary statements

Precautionary statement(s)
Pictogram(s)
Signal word	Danger
Hazard statement(s)	H314 Causes severe skin burns and eye damage H318 Causes serious eye damage
Prevention	P260 Do not breathe dust/fume/gas/mist/vapours/spray. P264 Wash ... thoroughly after handling. P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...
Response	P301+P330+P331 IF SWALLOWED: Rinse mouth. Do NOT induce vomiting. P363 Wash contaminated clothing before reuse. P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing. P316 Get emergency medical help immediately. P321 Specific treatment (see ... on this label). P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P305+P354+P338 IF IN EYES: Immediately rinse with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P317 Get medical help.
Storage	P405 Store locked up.
Disposal	P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.

Other hazards which do not result in classification

no data available

Handling and Storage

Precautions for safe handling

Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

Conditions for safe storage, including any incompatibilities

Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

See More Adenosine, 5′-[[(3S)-3-amino-3-carboxypropyl]methylsulfonio]-5′-deoxy-, sulfate, 4-methylbenzenesulfonate sulfate (1:1:1:1) Safety Data Sheet 

Seller Information

Business Type:
Manufactory

Main Products:
Semaglutide,Tirzepatide,HCG,Retatrutide,Cagrilintide,Medetomidine

Location:
RM702, Building 21, Liuhe Road, Ganjingzi Dist, Dalian, Liaoning, China

Payment Terms:
TT against copy of documents,L/C,TT against B/L draft before shipment,100% TT in advance

Average lead Time:
15

Total Annual Revenue:
$5 million-$10 million

Total Employees:
51-100

Year of Establishment:
2020

Dalian Handom Chemicals Co., Ltd.(HDC CHEM) is a professional 15-Year-Experienced Supplier of APIs & Intermediates, Pharmaceutical Excipients, Food & Nutraceutical Ingredients, Personal Care Chemicals and Specialty Chemicals from northeast of China, which strives to provide customers with high-quality products and comprehensive service across all over the world, our main products cover Retatrutide Lyophilized Powder, Retatrutide, Tirzepatide, Tirzepatide Lyophilized Powder, Semaglutide, Mazdutide, Cagrilintide, LL-37, Thymosin Alpha 1(Thymosin α1), MT-2, MOTS-c, HEP-1, TB-500, NAD+, GHK-Cu, Glow, Klow, Selank, Semax, Glutathione, 5-Amino-1MQ, ARA-290, SS-31, DSIP, SNAP-8, Medetomidine, Medetomidine Hydrochloride, Salcaprozate Sodium, Sodium 8-(2-hydroxybenzamido)octanoate, 2,6-Dimethyl Beta Cyclodextrin, mPEG-DMG-2K, mPEG-DSPE-2K, 1,2-Distearoyl-sn-3-phosphacholine(DSPC), 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine(DOPE), Pharmaceutical Grade Fructose, Lactose Anhydrous, Lactose Monohydrate, Orotic acid anhydrous, Orotic acid monohydrate, 6-Methyluracil, Chitosan, Mushroom Chitosan, Chitosan Hydrochloride, Chitosan Oligosaccharide, Alginate Oligosaccharide, Inulin, L-Serine, Mung Bean Peptide, Walnut Peptide, Rice Peptide, Oyster Peptide, Sea Cucumber Peptide, Hydrolyzed Keratin, Folic Acid, Vitamin E Acetate, Vitamin B2, Riboflavin Sodium Phosphate, Pyridoxal 5'-phosphate Monohydrate, Vegan Vitamin D3, Vitamin A Palmitate, Vitamin A Acetate, Apple Pectin, Citrus Pectin, Sunflower Pectin, Salidroside, Urolithin A, Milk Thistle Extract, Saffron Extract, Red Clover Extract, Sulforaphane, Glucoraphanin, Soy Isoflavones, Soy Lecithin, Soya Lecithin, Egg Yolk Lecithin, Phosphatidylserine, Cooling Agent WS-3, Cooling Agent WS-5, Cooling Agent WS-10, Cooling Agent WS-12, Cooling Agent WS-23, Cooling Agent WS-27, Menthyl Lactate, Menthyl PCA, Avobenzone, Benzophenone-3 (UV-9), Benzophenone-4 (UV-284), Bis-ethylhexyloxyphenol Methoxyphenyl Triazine (Bemotrizinol), Diethylaminohydroxybenzoyl Hexyl Benzoate (UVA Plus), Diethylhexyl Butamido Triazone (Iscotrizinol), Disodium Phenyl Dibenzimidazole Tetrasulfonate (DPDT), Ethylhexyl Triazone (UVT-150), Homosalate, Octocrylene, 2-Ethylhexyl Salicylate (Octyl Salicylate), 2-Ethylhexyl Trans-4-Methoxycinnamate (OMC), 2-Phenylbenzimidazole-5-Sulfonic Acid (UV-T), Lanolin Anhydrous, Palmitoyl Tripeptide-5, Dipeptide Diaminobutyroyl Benzylamide Diacetate, Biotinoyl Tripeptide-1, etc.
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