Pomegranate Peel Extract Ellagic acid 476-66-4
TDS
476-66-4
AAAAA
10%
长沙
STAHERB
1kg/2.6kg Carton (Required by Whyte Chemicals Sarl)
Yes
2023-09-16
plant extract,Fruit powder,herb extract,Carnosic acid,Chamomile P.E.,1-Deoxynojirimycin
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Product Description
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Seller Information
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DescriptionECHEMI Editorial ReferenceEllagic acid is a natural antioxidant, and acts as a potent and ATP-competitive CK2 inhibitor, with an IC50 of 40 nM and a Ki of 20 nM.
Ellagic acid appears as cream-colored needles (from pyridine) or yellow powder. Odorless. (NTP, 1992)|Solid
Ellagic acid appears as cream-colored needles (from pyridine) or yellow powder. Odorless. (NTP, 1992)|Ellagic acid is an organic heterotetracyclic compound resulting from the formal dimerisation of gallic acid by oxidative aromatic coupling with intramolecular lactonisation of both carboxylic acid groups of the resulting biaryl. It is found in many fruits and vegetables, including raspberries, strawberries, cranberries, and pomegranates. It has a role as an antioxidant, a food additive, a plant metabolite, an EC 5.99.1.2 (DNA topoisomerase) inhibitor, an EC 5.99.1.3 [DNA topoisomerase (ATP-hydrolysing)] inhibitor, an EC 1.14.18.1 (tyrosinase) inhibitor, an EC 2.3.1.5 (arylamine N-acetyltransferase) inhibitor, an EC 2.4.1.1 (glycogen phosphorylase) inhibitor, an EC 2.5.1.18 (glutathione transferase) inhibitor, an EC 2.7.1.127 (inositol-trisphosphate 3-kinase) inhibitor, an EC 2.7.1.151 (inositol-polyphosphate multikinase) inhibitor, an EC 2.7.4.6 (nucleoside-diphosphate kinase) inhibitor, a skin lightening agent, a fungal metabolite, an EC 2.7.7.7 (DNA-directed DNA polymerase) inhibitor and a geroprotector. It is an organic heterotetracyclic compound, a cyclic ketone, a lactone, a member of catechols and a polyphenol. It derives from a gallic acid.|Ellagic acid is present in several fruits such as cranberries, strawberries, raspberries, and pomegranates. In pomegranates, there are several therapeutic compounds but ellagic acid is the most active and abundant. Ellagic acid is also present in vegetables. Ellagic acid is an investigational drug studied for treatment of Follicular Lymphoma (phase 2 trial), protection from brain injury of intrauterine growth restricted babies (phase 1 and 2 trial), improvement of cardiovascular function in adolescents who are obese (phase 2 trial), and topical treatment of solar lentigines. Ellagic acid's therapeutic action mostly involves antioxidant and anti-proliferative effects.|A fused four ring compound occurring free or combined in galls. Isolated from the kino of Eucalyptus maculata Hook and E. Hemipholia F. Muell. Activates Factor XII of the blood clotting system which also causes kinin release; used in research and as a dye.CertificatesBasic Info-
Product Name:
Ellagic acid
Other Name:[1]Benzopyrano[5,4,3-cde][1]benzopyran-5,10-dione,2,3,7,8-tetrahydroxy-;2,3,7,8-Tetrahydroxy[1]benzopyrano[5,4,3-cde][1]benzopyran-5,10-dione;C.I. 55005;C.I. 75270;Alizarine Yellow;Benzoaric acid;Ellagic acid;Gallogen (astringent);[1,1′-Biphenyl]-2,2′-dicarboxylic acid,4,4′,5,5′,6,6′-hexahydroxy-,di-δ-lactone;Eleagic acid;Gallogen;Elagostasine;Lagistase;Alizarin yellow;G 91006;LDN 0097519;Ellagic acid LT;2,3,7,8-Tetrahydroxy-chromeno[5,4,3-cde]chromene-5,10-dione;124590-32-5;77415-21-5
CAS No.:476-66-4
Molecular Formula:C14H6O8
InChIKeys:InChIKey=AFSDNFLWKVMVRB-UHFFFAOYSA-N
Molecular Weight:302.19
Exact Mass:302.19
BRN:47549
EC Number:207-508-3
UNII:19YRN3ZS9P
NSC Number:758198|656272|407286
DSSTox ID:DTXSID2020557
Color/Form:Cream colored needles from pyridine
HScode:29322090
Categories:
Characteristics-
PSA:
134
XLogP3:1.1
Appearance:tan to gray powder
Density:2.1±0.1 g/cm3
Melting Point:>360 °C
Boiling Point:363.24°C (rough estimate)
Flash Point:310.1±26.4 °C
Refractive Index:1.895
Water Solubility:H2O: <0.1 g/100 mL at 21 ºC;1 M NaOH: 10 mg/mL, dark green
Storage Conditions:Store at RT
Vapor Pressure:2.81X10-15 mm Hg at 25 °C (est)
Toxicity:LD50 oral in rat: > 20gm/kg
Dissociation Constants:pKa1 = 6.69 (phenol); pKa2 = 7.45 (phenol); pKa3 = 9.61(phenol); pKa4 = 11.50 (phenol) (est)
Experimental Properties:Needles from acetic anhydride, mp 340 °C /Tetraacetate/|Hydroxyl radical reaction rate constant = 1.48X10-11 cu cm/molec-sec at 25 °C (est)
Air and Water Reactions:Insoluble in water.
Reactive Group:Esters, Sulfate Esters, Phosphate Esters, Thiophosphate Esters, and Borate Esters
Reactivity Profile:ELLAGIC ACID reacts as a weak acid. Incompatible with strong reducing substances such as hydrides, nitrides, alkali metals, and sulfides. Flammable gas (H2) is often generated. Heat is also generated by the acid-base reaction between phenols and bases. May be sulfonated exothermically very readily (for example, by concentrated sulfuric acid at room temperature). May be nitrated very rapidly, even by dilute nitric acid.
Hazard IdentificationClassification of the substance or mixture
Skin irritation, Category 2
Eye irritation, Category 2
Specific target organ toxicity â single exposure, Category 3
GHS label elements, including precautionary statements
Pictogram(s) 
Signal word Warning
Hazard statement(s) H315 Causes skin irritation
H319 Causes serious eye irritation
H335 May cause respiratory irritation
Precautionary statement(s) Prevention P264 Wash ... thoroughly after handling.
P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P271 Use only outdoors or in a well-ventilated area.
Response P302+P352 IF ON SKIN: Wash with plenty of water/...
P321 Specific treatment (see ... on this label).
P332+P317 If skin irritation occurs: Get medical help.
P362+P364 Take off contaminated clothing and wash it before reuse.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing.
P319 Get medical help if you feel unwell.
Storage P403+P233 Store in a well-ventilated place. Keep container tightly closed.
P405 Store locked up.
Disposal P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.
Other hazards which do not result in classification
no data available
Handling and StoragePrecautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.
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Seller Information
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Business Type:
Manufactory
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Main Products:
plant extract,Fruit powder,herb extract,Carnosic acid,Chamomile P.E.,1-Deoxynojirimycin
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Location:
No.186,Lugu Valley Garden Road, High-tech Development Zone, Changsha , Hunan, P.R. China
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Payment Terms:
TT against copy of documents,L/C
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Average lead Time:
120 days
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Total Annual Revenue:
$2.5 million-$5 million
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Total Employees:
11-50
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Year of Establishment:
2010
Changsha Staherb Natural Ingredients Co., Ltd., a good supplier of professional herb extracts, especially those with high purity and standardized production process. Our company devotes to supply high quality products and services to customers in R&D and production fields of health products, cosmetics, feed additives and biopesticides.
With cordial and professional R&D, sales and after-sales service groups, Staherb has potent capabilities both in R&D and production. The company persists in high investment on R&D of active ingredients of plants and promotes innovation on demands of customers. Upon constant R&D and tracing of new technologies and new products, Staherb makes effective cooperation with famous research institutes, such as CAS Kunming Institute of Botany, State Key Lab of Hunan Forest Products and Chemical Engineering, Hunan Agricultural University and so on.
Now the main products of Staherb are standardized high purity plant extracts, including Epimedium (10-98%), Euccomia Bark Extract (5-95%), Amygdalin (50-98%), Ursolic acid (25-98%) and Corosolic acid (1-98%). In order to meet customers’ research needs, our company also provides over 600 plant extracts, most of which are high-purity monomer plant compounds and reference substance. And some products can be supplied with milligram-scale, kilogram-scale or even to ton-scale. In addition, based upon the powerful R&D capability, Staherb can provide both products customization services and R&D outsourcing services according to customers’ specific requirements, so that to meet their continual innovation needs in the fields of natural products’ discovery and production.
Staherb endeavors to accelerate the response rate of supply chain as well as improve the service superiority upon customers’ continual innovation needs. It also devotions to establish good partnerships with customers and to construct a safe development model which is forward-looking, reciprocal and coexisting, thus to create long-term value for customers through division and cooperation as well as complementation. -
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