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Nepafenac

1 Inquiries

Unit Price: Get Latest Price
CAS No.:

78281-72-8

Grade:

Pharmaceutical Grade

Content:

99%

Port:

ShangHai

Packaging:

drums

Sample Available:

Yes

Price valid (until):

2023-11-12

Company Type:
Trader
Location:
China
Payment Terms:
TT against copy of documents,L/C,TT against B/L draft before shipment,100% TT in advance
Average Lead Time:
15 days
Qualification:
Main Products:

Di-n-butyl naphthalene-2,6-dicarboxylate

  • Product Details

  • Seller Information

  • Inquiry History

  • Description


      Product Detail  


    Nepafenac is a non-steroidal anti-inflammatory drug (NSAID), usually sold as a prescription eye drop. It reduces pain and inflammation in the eyes. Nepafenac ophthalmic is used to reduce pain and swelling after cataract surgery.

    Items Specifications
    Melting point  177-181°C
    Boiling point  562.5±50.0 °C(Predicted)
    density 1.249±0.06 g/cm3(Predicted)
    storage temp.  room temp
    solubility  DMSO: ≥5mg/mL
    pka 16.09±0.40(Predicted)
    form  powder
    color  faint yellow to dark yellow
    Water Solubility 0.014 mg/mL in water
    ECHEMI Editorial Reference
    Nepafenac(AHR 9434; AL 6515; Nevanac) is a selective COX-2 inhibitor; is prodrug of Amfenac.IC50 value:Target: COX-2Nepafenac is a NSAID (nonsteroidal anti inflammatory drug) that is routinely used in opthamology to control pain following cataract surgery.
    Solid
    Nepafenac is a monocarboxylic acid amide that is amfenac in which the carboxylic acid group has been converted into the corresponding carboxamide. It is a prodrug for amfenac, used in eye drops to treat pain and inflammation following cataract surgery. It has a role as a prodrug, a cyclooxygenase 2 inhibitor, a cyclooxygenase 1 inhibitor, a non-steroidal anti-inflammatory drug and a non-narcotic analgesic.|Nepafenac is a non-steroidal anti-inflammatory prodrug (NSAID) usually sold as a prescription eye drop. It is used to treat pain and inflammation associated with cataract surgery.|Nepafenac is a Nonsteroidal Anti-inflammatory Drug. The mechanism of action of nepafenac is as a Cyclooxygenase Inhibitor.|Nepafenac is a topical nonsteroidal anti-inflammatory drug that is used in eye drops for the treatment of eye pain and swelling.

    Basic Info
    Product Name:

    Nepafenac

    Other Name:

    Benzeneacetamide,2-amino-3-benzoyl-;2-Amino-3-benzoylbenzeneacetamide;AL 6515;Nepafenac;AHR 9434;Nevanac;Ilevro;2-(2-Amino-3-benzoylphenyl)acetamide

    CAS No.:

    78281-72-8

    Molecular Formula:

    C15H14N2O2

    InChIKeys:

    InChIKey=QEFAQIPZVLVERP-UHFFFAOYSA-N

    Molecular Weight:

    254.28400

    Exact Mass:

    254.28

    UNII:

    0J9L7J6V8C

    DSSTox ID:

    DTXSID0048638

    NCI Thesaurus Code:

    C66228

    ATC Code:

    S01BC10|S - Sensory organs

    HScode:

    2924299090

    Characteristics
    PSA:

    86.18000

    XLogP3:

    1.9

    Appearance:

    Solid

    Density:

    1.249 g/cm3

    Melting Point:

    178-180 °C @ Solvent: Isopropanol

    Boiling Point:

    562.5ºC at 760 mmHg

    Flash Point:

    294ºC

    Refractive Index:

    1.641

    Storage Conditions:

    Refrigerator

    Hazard Identification

    Classification of the substance or mixture

    Hazardous to the aquatic environment, short-term (Acute) - Category Acute 1

    GHS label elements, including precautionary statements

    Pictogram(s)
    Signal word

    Warning

    Hazard statement(s)

    H400 Very toxic to aquatic life

    Precautionary statement(s)
    Prevention

    P273 Avoid release to the environment.

    Response

    P391 Collect spillage.

    Storage

    none

    Disposal

    P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.

    Other hazards which do not result in classification

    no data available

    Handling and Storage

    Precautions for safe handling

    Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

    Conditions for safe storage, including any incompatibilities

    Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

  • Seller Information
    Business Type:

    Trader

    Main Products:

    Di-n-butyl naphthalene-2,6-dicarboxylate

    Location:

    1208# HuaCe Building-B,Wuchanggang Road,XIHU District,Hangzhou City,Zhejiang Province ,China

    Payment Terms:

    TT against copy of documents,L/C,TT against B/L draft before shipment,100% TT in advance

    Average lead Time:

    15 days

    Total Annual Revenue:

    $5 million-$10 million

    Total Employees:

    5-10

    Year of Establishment:

    2023

  • Inquiry History
    1 Inquiries
    Country Product Purchase Quantity Date Posted
    Pakistan

    NEPAFENAC

    1 KG May 13, 2026
    Post an enquiry for this product
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