99% Raw Material Sumatriptan Succinate 103628-46-2 Pharmaceutical Powder Sumatriptan
KOSHER ISO FDA 1 Inquiries
103628-46-2
Food grade
99%
shen zhen
Flying
10g/1kg/ 10kg/ 25kg
2023-11-16
vitamin
-
Product Description
-
Seller Information
-
Inquiry History
-
DescriptionECHEMI Editorial ReferenceChEBI: A sulfonamide that consists of N,N-dimethyltryptamine bearing an additional (N-methylsulfamoyl)methyl substituent at position 5. Selective agonist for a vascular 5-HT1 receptor s btype (probably a member of the 5-HT1D family). Used (in the form of its succinate salt) for the acute treatment of migraine with or without aura in adults.Sumatriptan was the first triptan approved (1991) for theacute treatment of migraine headaches. It has the lowestoral bioavailability among all triptans bec
Solid
Sumatriptan is a sulfonamide that consists of N,N-dimethyltryptamine bearing an additional (N-methylsulfamoyl)methyl substituent at position 5. Selective agonist for a vascular 5-HT1 receptor subtype (probably a member of the 5-HT1D family). Used (in the form of its succinate salt) for the acute treatment of migraine with or without aura in adults. It has a role as a serotonergic agonist and a vasoconstrictor agent. It is a sulfonamide and a member of tryptamines. It derives from a N,N-dimethyltryptamine. It is a conjugate acid of a sumatriptan(1+).|Sumatriptan is a serotonin receptor agonist commonly used to treat migraines and sometimes cluster headaches. Sumatriptan is the first of the triptans and was made available in Europe in 1991 to treat migraines. Sumatriptan was granted FDA approval on 28 December 1992.|Sumatriptan is a Serotonin-1b and Serotonin-1d Receptor Agonist. The mechanism of action of sumatriptan is as a Serotonin 1b Receptor Agonist, and Serotonin 1d Receptor Agonist.|The triptans are a group of serotonin receptor agonists that are useful in the therapy of vascular headaches and migraine. The triptans are generally used in low doses for a limited period of time and have not been associated with serum enzyme elevations, but some have been implicated in rare instances of clinically apparent, acute cholestatic hepatitis.|Sumatriptan is a sulfonamide triptan with vasoconstrictor activity. Sumatriptan selectively binds to and activates serotonin 5-HT1D receptors in the central nervous system (CNS), thereby constricting cerebral blood vessels. This may lead to a relief in pain from vascular headaches. Sumatriptan may also relieve vascular headaches by decreasing the release of vasoactive neuropeptides from perivascular trigeminal axons in the dura mater during a migraine, by reducing extravasation of plasma proteins, and by decreasing the release of other mediators of inflammation from the trigeminal nerve.|A serotonin agonist that acts selectively at 5HT1 receptors. It is used in the treatment of MIGRAINE DISORDERS.CertificatesBasic Info-
Product Name:
Sumatriptan
Other Name:1H-Indole-5-methanesulfonamide,3-[2-(dimethylamino)ethyl]-N-methyl-;3-[2-(Dimethylamino)ethyl]-N-methyl-1H-indole-5-methanesulfonamide;Sumatriptan;GR 43175X;GR 43175;Zelrix;3-[2-(Dimethylamino)ethyl]-N-methylindolyl-5-methanesulfonamide;Onzetra Xsail;Zecuity;1-[3-[2-(Dimethylamino)ethyl]-1H-indol-5-yl]-N-methylmethanesulfonamide
CAS No.:103628-46-2
Molecular Formula:C14H21N3O2S
InChIKeys:InChIKey=KQKPFRSPSRPDEB-UHFFFAOYSA-N
Molecular Weight:295.4
Exact Mass:295.40
UNII:8R78F6L9VO
DSSTox ID:DTXSID4023628
NCI Thesaurus Code:C1240
ATC Code:N02CC01|N - Nervous system
HScode:2935904000
Categories:
Characteristics-
PSA:
73.6
XLogP3:0.93
Appearance:Solid
Density:1.1778 (rough estimate)
Melting Point:169-171 °C
Boiling Point:497.7±55.0 °C(Predicted)
Flash Point:254.8±31.5 °C
Refractive Index:1.6740 (estimate)
Water Solubility:H2O: 21.4 mg/mL;40.3 [ug/mL]
Storage Conditions:Sumatriptan succinate injection and tablets and sumatriptan nasal spray should be protected from light and stored at 2-30 deg C.
Vapor Pressure:7.05X10-9 mm Hg at 25 deg C (est)
PKA:4.9None
Henrys Law Constant:Henry's Law constant = 4.47X10-14 atm-cu m/mol at 25 °C (est)
Dissociation Constants:4.9|pKa = 10.4 (est) (amide)
Collision Cross Section:162.1 Ų [M+H]+ [CCS Type: TW, Method: Major Mix IMS/Tof Calibration Kit (Waters)]
Experimental Properties:MW: 413.49; mp 165-166 °C /Sumatriptan succinate/
Hazard IdentificationClassification of the substance or mixture
Reproductive toxicity, Category 2
Hazardous to the aquatic environment, long-term (Chronic) - Category Chronic 3
GHS label elements, including precautionary statements
Pictogram(s) 
Signal word Warning
Hazard statement(s) H361 Suspected of damaging fertility or the unborn child
H412 Harmful to aquatic life with long lasting effects
Precautionary statement(s) Prevention P203 Obtain, read and follow all safety instructions before use.
P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...
P273 Avoid release to the environment.
Response P318 IF exposed or concerned, get medical advice.
Storage P405 Store locked up.
Disposal P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.
Other hazards which do not result in classification
no data available
Handling and StoragePrecautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.
-
-
Seller Information
-
Business Type:
Trader
-
Main Products:
vitamin
-
Location:
Room 2-502, Building 6, Luneng Tehran Garden Building, No.8 Changbin Road, Xiuying district, Haikou City, Hainan Province
-
Payment Terms:
TT against copy of documents,TT against B/L draft before shipment
-
Average lead Time:
25
-
Total Annual Revenue:
$2.5 million-$5 million
-
Total Employees:
Less than 5
-
Year of Establishment:
2023
-
-
Inquiry History1 Inquiries
Country Product Purchase Quantity Date Posted 
Saudi Arabia
Sumatriptan
300 KG May 11, 2026 Post an enquiry for this product
