Factory Price Pregabalin 99 % powder CAS 148553-50-8 in Stock junjia
TDS 279 Inquiries
148553-50-8
Industrial Grade
99%
customer negotiation
junjia
2mg / 5mg / 10mg / 15mg /vial , 10 vials / box
Yes
2024-12-30
Blue copper peptide powder
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Product Description
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Seller Information
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Inquiry History
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DescriptionECHEMI Editorial ReferenceOff-White SolidPregabalin is a second- generation antiepileptic drug (AED) known with the proprietary brand name of Lyrica (Pfizer, Tadworth) in the UK and USA (Pfizer, New York, NY). As a follow-up to its g-aminobutyric acid (GABA) agonist gabapentin, Pfizer hasdeveloped and launched pregabalin for the treatment of epilepsy and neuropathicpain. Although pregabalin is a structural analog of GABA, it does not interact withGABA-A or GABA-B receptors or influence GABA uptake. The exact mec
Solid
Pregabalin is a gamma-amino acid that is gamma-aminobutyric acid (GABA) carrying an isobutyl substitutent at the beta-position (the S-enantiomer). Binds with high affinity to the alpha2-delta site (an auxiliary subunit of voltage-gated calcium channels) in central nervous system tissues. It has a role as an anticonvulsant and a calcium channel blocker. It derives from a gamma-aminobutyric acid.|Pregabalin is a DEA Schedule V controlled substance. Substances in the DEA Schedule V have a low potential for abuse relative to substances listed in Schedule IV and consist primarily of preparations containing limited quantities of certain narcotics.|Pregabalin is structurally similar to gamma-aminobutyric acid (GABA) - an inhibitory neurotransmitter. It may be used to manage neuropathic pain, postherpetic neuralgia, and fibromyalgia among other conditions. Although as per the FDA Label the mechanism of action has not been definitively defined, there is evidence that pregabalin exerts its effects by binding to the α2δ subunit of voltage-dependent calcium channels. Pregabalin is marketed by Pfizer under the trade name Lyrica and Lyrica Cr (extended release). It may have dependence liability if misused but the risk appears to be highest in patients with current or past substance use disorders.|Pregabalin is an inhibitor of neuronal activity used for therapy of painful neuropathy and as an anticonvulsant. Therapy with pregabalin is not associated with serum aminotransferase elevations, and clinically apparent liver injury from pregabalin has been reported but appears to be quite rare.|Pregabalin is a 3-isobutyl derivative of gamma-amino butyric acid (GABA) with anti-convulsant, anti-epileptic, anxiolytic, and analgesic activities. Although the exact mechanism of action is unknown, pregabalin selectively binds to alpha2delta (A2D) subunits of presynaptic voltage-dependent calcium channels (VDCCs) located in the central nervous system (CNS). Binding of pregabalin to VDCC A2D subunits prevents calcium influx and the subsequent calcium-dependent release of various neurotransmitters, including glutamate, norepinephrine, serotonin, dopamine, and substance P, from the presynaptic nerve terminals of hyperexcited neurons; synaptic transmission is inhibited and neuronal excitability is diminished. Pregabalin does not bind directly to GABA-A or GABA-B receptors and does not alter GABA uptake or degradation.|A gamma-aminobutyric acid (GABA) derivative that functions as a CALCIUM CHANNEL BLOCKER and is used as an ANTICONVULSANT as well as an ANTI-ANXIETY AGENT. It is also used as an ANALGESIC in the treatment of NEUROPATHIC PAIN and FIBROMYALGIA.CertificatesBasic Info-
Product Name:
Pregabalin
Other Name:Hexanoic acid,3-(aminomethyl)-5-methyl-,(3S)-;Hexanoic acid,3-(aminomethyl)-5-methyl-,(S)-;(3S)-3-(Aminomethyl)-5-methylhexanoic acid;PD 144723;CI 1008;Pregabalin;Lyrica;(S)-Pregabalin;(S)-(+)-3-(Aminomethyl)-5-methylhexanoic acid;(2S)-3-(Aminomethyl)-5-methylhexanoic acid;Gabanext 75;Pregalin 75;Neugaba 75;Maxgalin 75;Mahagaba-75;(S)-3-(Aminomethyl)-5-methylhexanoic acid
CAS No.:148553-50-8
Molecular Formula:C8H17NO2
InChIKeys:InChIKey=AYXYPKUFHZROOJ-ZETCQYMHSA-N
Molecular Weight:159.22600
Exact Mass:159.23
EC Number:604-639-1
UNII:55JG375S6M
DEA Code Number:2782
DSSTox ID:DTXSID1045950
NCI Thesaurus Code:C64625
Color/Form:White to off-white crystalline solid
ATC Code:N03AX16|QN03AX16|N - Nervous system
HScode:2915900090
Categories:
Characteristics-
PSA:
63.32000
XLogP3:1.78240
Appearance:Solid
Density:0.997 g/cm3
Melting Point:195 °C (decomp) @ Solvent: Isopropanol
Boiling Point:274ºC at 760 mmHg
Flash Point:119.5ºC
Refractive Index:1.464
Water Solubility:deionized water: ≥10mg/mL
Storage Conditions:Store at 25 deg C (77 deg F); excursions permitted to 15 to 30 deg C (59 to 86 deg F).
Vapor Pressure:0.00153mmHg at 25°C
Specific rotation:Specific optical rotation = +10.52 deg/D (c = 1.00 in water)
Henrys Law Constant:Henry's Law constant = 6.89X10-11 atm-cu m/mol at 25 °C (est)
Dissociation Constants:pKa1 = 4.2; pKa2 = 10.6
Experimental Properties:The log of the partition coefficient (n-octanol/0.05M phosphate buffer) at pH 7.4 is -1.35|Hydroxyl radical reaction rate constant = 4.1X10-11 cu cm/molec-sec at 25 °C (est)
Hazard IdentificationClassification of the substance or mixture
Serious eye damage, Category 1
Reproductive toxicity, Category 2
Specific target organ toxicity â repeated exposure, Category 2
GHS label elements, including precautionary statements
Pictogram(s) 
Signal word Danger
Hazard statement(s) H318 Causes serious eye damage
H361 Suspected of damaging fertility or the unborn child
H373 May cause damage to organs through prolonged or repeated exposure
Precautionary statement(s) Prevention P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...
P203 Obtain, read and follow all safety instructions before use.
P260 Do not breathe dust/fume/gas/mist/vapours/spray.
Response P305+P354+P338 IF IN EYES: Immediately rinse with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P317 Get medical help.
P318 IF exposed or concerned, get medical advice.
P319 Get medical help if you feel unwell.
Storage P405 Store locked up.
Disposal P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.
Other hazards which do not result in classification
no data available
Handling and StoragePrecautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.
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Seller Information
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Business Type:
Trader
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Main Products:
Blue copper peptide powder
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Location:
Shanghai
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Payment Terms:
TT against copy of documents,D/P,L/C,D/A,O/A,TT against B/L draft before shipment,100% TT in advance
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Average lead Time:
3 days
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Total Annual Revenue:
Less than $1 million
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Total Employees:
11-50
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Year of Establishment:
2023
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Inquiry History279 Inquiries
Country Product Purchase Quantity Date Posted 
Oman
White Crystalline powder Pregabalin Lyrica 148553-50-8 HALAL ISO
1 KG Jan 16, 2024 
United Arab Emirates
Pregabalin CAS 148553-50-8
1 KG Jan 20, 2024 
United States
Pregabalin powder CAS 148553-50-8
3 G Oct 29, 2023
United States
High Quality Pregabalin 99% powder 148553-50-8
222 G Jul 4, 2024 
Poland
Research Chemical 99.5% Pregabalin Powder CAS: 148553-50-8
100 G Nov 9, 2023
United States
Best Price Pregabalin CAS 148553-50-8 In Stock
1 G Nov 4, 2023 
Algeria
99% White Crystalline powder Pregabalin Lyrica 148553-50-8
400 G Jun 11, 2025
United States
99% White Crystalline powder Pregabalin Lyrica 148553-50-8
1 MT Nov 18, 2023 
Saudi Arabia
hot sell pregabalin lyrica pregabalin powder CAS 148553-50-8
300 G Oct 22, 2023 
Sweden
High Purity Pregabalin CAS 148553-50-8 Crystalline powder
500 G Feb 16, 2026 
Lebanon
Pregabalin 99% White Powder CAS 148553-50-8 Pregabalin powder
1 KG Dec 4, 2023 
Qatar
hot sell pregabalin lyrica pregabalin powder CAS 148553-50-8
1 MT Nov 5, 2023
United Arab Emirates
hot sell pregabalin lyrica pregabalin powder CAS 148553-50-8
1 KG Nov 1, 2023 
Turkey
High Purity in Stock Pregabalin CAS 148553-50-8 99%
100 KG Oct 29, 2023
United States
Pregabalin Crystal CAS 148553-50-8 Lyrica Powder 99.0% White Powder Mobelbiochem
50 G Feb 17, 2026
United Arab Emirates
factory price hot sell pregabalin lyrica 99.9% powder 99 likes 148553-50-8
3 KG Nov 20, 2023
United Arab Emirates
factory price hot sell pregabalin lyrica 99.9% powder 99 likes 148553-50-8
20 G Nov 20, 2023
Saudi Arabia
Pregabalin 99% White Crystalline Powder 148553-50-8 From Biocar Pregabalin 99% White Crystalline Pow
200 G Sep 4, 2026 
Malta
Pregabalin
25 MT Aug 30, 2026
Sweden
Pregabalin
1 KG Sep 3, 2026 Post an enquiry for this product
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