High purity Various Specifications Fluorescein CAS NO.2321-07-5
9 Inquiries
2321-07-5
Pharmaceutical Grade
99%
shanghai
Lonwin
1kg/bag,25kg/drum,25kg/bag
2023-12-21
CHEMICALS,REAGENTS
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Product Description
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Seller Information
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Inquiry History
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DescriptionECHEMI Editorial ReferenceFluorescein is a synthetic fluorescent tracer.
Fluorescein is a synthetic organic compound available as a dark orange/red powder slightly soluble in water and alcohol. It is widely used as a fluorescent tracer for many applications.
Fluorescein appears as yellow amorphous solid or orange-red crystals. Latter have greenish-yellow fluorescence by reflected light. Insoluble in water. Soluble in dilute aqueous bases. Very dilute alkaline solutions exhibit intense, greenish-yellow fluorescence by reflected light. Low toxicity. May be sensitive to prolonged exposure to light.|Solid
Fluorescein appears as yellow amorphous solid or orange-red crystals. Latter have greenish-yellow fluorescence by reflected light. Insoluble in water. Soluble in dilute aqueous bases. Very dilute alkaline solutions exhibit intense, greenish-yellow fluorescence by reflected light. Low toxicity. May be sensitive to prolonged exposure to light.|Fluorescein (lactone form) is a xanthene dye that is highly fluorescent, detectable even when present in minute quantities. Used forensically to detect traces of blood, in analytical chemistry as an indicator in silver nitrate titrations and in microscopy. It has a role as a radioopaque medium and a fluorescent dye. It is a xanthene dye, a gamma-lactone, a polyphenol, an oxaspiro compound, a member of 2-benzofurans and an organic heteropentacyclic compound. It derives from a fluorescein (acid form).|A phthalic indicator dye that appears yellow-green in normal tear film and bright green in a more alkaline medium, such as the aqueous humor, and is used therapeutically as a diagnostic aid in corneal injuries and corneal trauma. It has been approved by FDA for use in externally applied drugs and cosmetics. (From Merck Index, 12th ed; American Medical Association Drug Evaluations; 1995, p2275)|Fluorescein is a Diagnostic Dye. The mechanism of action of fluorescein is as a Dye.|Fluorescein is an organic compound that has wide use as a synthetic coloring agent. It is prepared by heating phthalic anhydride and resorcinol over a zinc catalyst, and it crystallizes as a deep red powder. This agent emits an intense green fluorescence in the presence of alkaline solutions and therefore is used as a label when conjugated to antibodies or as a contrast agent for ophthalmic angiography.|A phthalic indicator dye that appears yellow-green in normal tear film and bright green in a more alkaline medium such as the aqueous humor.
ChEBI: A xanthene dye that is highly fluorescent, detectable even when present in minute quantities. Used forensically to detect traces of blood, in analytical chemistry as an indicator in silver nitrate titrations and in microscopy.Basic Info-
Product Name:
Fluorescein
Other Name:FLUORESCEIN, FREE ACIDFLUORESCEIN, FREE ACIDFLUORESCEIN, FREE ACID;Diresorcinolphthalein;Tetraoxyphthalophenone anhydride;SOLVENT YELLOW 94;S NO 880;RESORCINOL PHTHALEIN;FLUORESCEIN, ALCOHOL SOLUBLE;FLUORESCEIN
CAS No.:2321-07-5
Molecular Formula:C20H12O5
InChIKeys:GNBHRKFJIUUOQI-UHFFFAOYSA-N
Molecular Weight:332.31
Exact Mass:332.31
BRN:94324
EC Number:219-031-8
UNII:TPY09G7XIR
NSC Number:759114|667256
TSCA:TSCA listed
DSSTox ID:DTXSID0038887
NCI Thesaurus Code:C61766
Color/Form:Red to orange
ATC Code:S01JA01|S - Sensory organs
HScode:32042000
Categories:
Characteristics-
λmax:
493.5nm, 496nm, 460nm, 515nm
PSA:87.74000
Physical Properties:The fluorescence of this molecule is very intense; peak excitation occurs at 494 nm and peak emission at 521 nm.Fluorescein has a pKa of 6.4, and its ionization equilibrium leads to pH-dependent absorption and emission over the range of 5 to 9. Also, the fluorescence lifetimes of the protonated and deprotonated forms of fluorescein are approximately 3 and 4 ns, which allows for pH determination from non intensity based measurements. The lifetimes can be recovered using time-correlated single photon counting or phase-modulation fluorimetry.
XLogP3:3.4
Appearance:Red to orange Powder
Density:1.2739 (rough estimate)
Melting Point:320 °C(lit.)
Boiling Point:429.44°C (rough estimate)
Flash Point:232.6±25.0 °C
Refractive Index:1.5000 (estimate)
Water Solubility:insoluble
Storage Conditions:−20°C
Vapor Pressure:4.1X10-14 mm Hg at 25 deg C (est)
PKA:2.2, 4.4, 6.7(at 25℃)
Henrys Law Constant:1.1×1011mol/(m3Pa) at 25℃, HSDB (2015)
Collision Cross Section:172.3 Ų [M+H]+ [CCS Type: TW, Method: calibrated with polyalanine and drug standards]
Experimental Properties:Fluorescein is a fluorescent indicator. From pH 4 to pH 4.5, it changes from colorless to green fluorescent.|Hydroxyl radical reaction rate constant = 2.0X10-10 cu cm/molec-sec at 25 °C (est)
Air and Water Reactions:Insoluble in water.
Reactive Group:Acids, Carboxylic
Reactivity Profile:Fluorescein is incompatible with strong oxidizers. Also incompatible with acids, acid salts and salts of heavy metals. .
Critical Temperature & Pressure:room temp
Hazard IdentificationClassification of the substance or mixture
Eye irritation, Category 2
GHS label elements, including precautionary statements
Pictogram(s)
Signal word Warning
Hazard statement(s) H319 Causes serious eye irritation
Precautionary statement(s) Prevention P264 Wash ... thoroughly after handling.
P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...
Response P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
Storage none
Disposal none
Other hazards which do not result in classification
no data available
Handling and StoragePrecautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.
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Seller Information
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Business Type:
Trader
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Main Products:
CHEMICALS,REAGENTS
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Location:
No 966 Huaxu Road, Qingpu District, Shanghai, 201702, P.R. China
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Payment Terms:
TT against copy of documents,L/C,TT against B/L draft before shipment,100% TT in advance
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Average lead Time:
10
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Total Annual Revenue:
$10 million-$25 million
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Total Employees:
11-50
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Year of Establishment:
2011
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Inquiry History9 Inquiries
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