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D-Tetrandrine

Unit Price: Get Latest Price
CAS No.:

518-34-3

Grade:

Industrial Grade

Content:

98%

Brand:

CUIKANG

Packaging:

G/bottle; Kg/bag; 25kg/barrel

Price valid (until):

2025-01-30

Company Type:
Manufactory
Location:
China
Qualification:
Main Products:

Cosmetics raw materials,Pesticide intermediate,Photoelectric material,pharmaceutical intermediates,Raw materials for food and health products,Polymer materials

  • Product Description

  • Seller Information

  • Description


      Product Detail  


    Uses: Antirheumatic and analgesic drugs for rheumatism, hypertension, lung cancer, etc. Antirheumatic and analgesic drugs used in the treatment of rheumatism, hypertension, lung cancer and other diseases

    Apply
    1. The immune system disease tetrandrine can significantly inhibit the development of arthritis and has a stronger effect than aspirin, which can be applied to the treatment of rheumatoid arthritis.
    2. In cardiovascular diseases, tetrandrine not only has calcium antagonism, can inhibit T and L calcium channels in ventricular myocytes, but also interacts with M receptors to block calcium-activated potassium channels, becoming a treatment method for paroxysmal supraventricular tachycardia.
    3. Tetrandrine in digestive system plays a certain role in protecting liver cells and anti-liver fibrosis.
    4. Ophthalmic diseases Hantetrandrine is used for the treatment of eye inflammation, including uveitis, keratitis and the resulting retinopathy.
    5. Tetrandrine has an obvious antagonistic effect on acute renal toxicity induced by streptomycin, can reduce the apoptosis and proliferation of renal tubular epithelial cells, protect renal function, protect acute ischemia-reperfusion renal injury, significantly reduce serum creatinine and urea nitrogen levels, improve glomerular filtration rate and renal plasma flow, and delay the development of glomerular sclerosis. Summary, physicochemical properties, pharmacological action and application of tetrandrine




    Items Specifications






    Basic Info
    Product Name:

    Tetrandrine

    Other Name:

    16H-1,24:6,9-Dietheno-11,15-metheno-2H-pyrido[2′,3′:17,18][1,11]dioxacycloeicosino[2,3,4-ij]isoquinoline,3,4,4a,5,16a,17,18,19-octahydro-12,21,22,26-tetramethoxy-4,17-dimethyl-,(4aS,16aS)-;Tetrandrine;Berbaman,6,6′,7,12-tetramethoxy-2,2′-dimethyl-,(1β)-;(4aS,16aS)-3,4,4a,5,16a,17,18,19-Octahydro-12,21,22,26-tetramethoxy-4,17-dimethyl-16H-1,24:6,9-dietheno-11,15-metheno-2H-pyrido[2′,3′:17,18][1,11]dioxacycloeicosino[2,3,4-ij]isoquinoline;d-Tetrandrine;NSC 77037;(+)-Tetrandrine;Tetrandrin;(S,S)-Tetrandrine;Sinomenine A;Fanchinine;16H-1,24:6,9-Dietheno-11,15-metheno-2H-pyrido[2′,3′:17,18][1,11]dioxacycloeicosino[2,3,4-ij]isoquinoline,3,4,4a,5,16a,17,18,19-octahydro-12,21,22,26-tetramethoxy-4,17-dimethyl-,[4aS-(4aR*,16aR*)]-;TTD;S,S-(+)-Tetrandrine;Hanfangchin A;5990-67-0;6490-80-8;607379-81-7;916770-74-6;1217517-04-8

    CAS No.:

    518-34-3

    Molecular Formula:

    C38H42N2O6

    InChIKeys:

    InChIKey=WVTKBKWTSCPRNU-KYJUHHDHSA-N

    Molecular Weight:

    622.75

    Exact Mass:

    622.75

    EC Number:

    1806241-263-5

    UNII:

    29EX23D5AJ

    NSC Number:

    91771|77037

    DSSTox ID:

    DTXSID10178062

    NCI Thesaurus Code:

    C28952

    HScode:

    2942000000

    Categories:

    Plant Extracts

    Characteristics
    PSA:

    61.9

    XLogP3:

    6.4

    Appearance:

    solid

    Density:

    1.2±0.1 g/cm3

    Melting Point:

    217.5 °C

    Boiling Point:

    710.5°C at 760 mmHg

    Flash Point:

    175.8±30.1 °C

    Refractive Index:

    1.586

    Storage Conditions:

    Keep container tightly closed. Keep container in a cool, well-ventilated area. Do not store above 20ºC.

    Specific rotation:

    285 º (c=1, CHCl3)

    Collision Cross Section:

    245.3 Ų [M+H]+ [CCS Type: TW, Method: calibrated with polyalanine and drug standards]

    Hazard Identification

    Classification of the substance or mixture

    Acute toxicity - Category 4, Oral

    GHS label elements, including precautionary statements

    Pictogram(s)
    Signal word

    Warning

    Hazard statement(s)

    H302 Harmful if swallowed

    Precautionary statement(s)
    Prevention

    P264 Wash ... thoroughly after handling.

    P270 Do not eat, drink or smoke when using this product.

    Response

    P301+P317 IF SWALLOWED: Get medical help.

    P330 Rinse mouth.

    Storage

    none

    Disposal

    P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.

    Other hazards which do not result in classification

    no data available

    Handling and Storage

    Precautions for safe handling

    Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

    Conditions for safe storage, including any incompatibilities

    Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

  • Seller Information
    Business Type:

    Manufactory

    Main Products:

    Cosmetics raw materials,Pesticide intermediate,Photoelectric material,pharmaceutical intermediates,Raw materials for food and health products,Polymer materials

    Location:

    D307, Zhuque Square Office Building, No. 14, Chang'an North Road, Beilin District, Xi'an City, Shaanxi Province

    Payment Terms:

    TT against copy of documents,TT against B/L draft before shipment,100% TT in advance

    Average lead Time:

    45

    Total Annual Revenue:

    Less than $1 million

    Total Employees:

    11-50

    Year of Establishment:

    2023

    Certifications:

    ISO,ISO,ISO

    Shaanxi Cuikang Pharmaceutical Technology Co., Ltd., founded in January 2023, is a wholly-owned subsidiary of Shaanxi Cuicheng Bio-pharmaceutical Technology Co., Ltd., and a comprehensive innovative enterprise focusing on the research and development, production, sales, import and export trade, technical services and related resource allocation and integration of products in the field of fine chemistry and biochemistry. The company has built a 2700 square meter R&D center in Hanzhong, Shaanxi Province, and has established in-depth and stable cooperative relations with three factories, which can provide one-stop service for domestic and foreign customers from pilot R&D to industrial scale-up production.

    Cuikang Company is an enterprise integrating natural products, fine chemicals, biological fermentation, innovative material research and development, production, sales and technical services. It can provide global customers with a series of products with different specifications and models, such as proportional plant extracts, content plant extracts, synthetic chemical blocks, synthetic pharmaceutical intermediates, active API molecules, fermented pharmaceutical intermediates and APIs, health food, functional food raw materials, veterinary drug raw materials, pharmaceutical innovative materials, laboratory equipment, pharmaceutical machinery and equipment.

    The company adheres to the market demand-oriented, technical innovation as the starting point, product quality as the core, customer service as the foundation, and the enterprise spirit of "professional integrity", and wholeheartedly provides high-quality products and services for customers at home and abroad.


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