NOCODAZOLE
31430-18-9
Industrial Grade
98%
CUIKANG
G/bottle; Kg/bag; 25kg/barrel
Yes
2025-01-30
Cosmetics raw materials,Pesticide intermediate,Photoelectric material,pharmaceutical intermediates,Raw materials for food and health products,Polymer materials
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Product Description
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Seller Information
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DescriptionECHEMI Editorial ReferenceNocodazole is a rapidly-reversible inhibitor of microtubule. Nocodazole binds to β-tubulin and disrupts microtubule assembly/disassembly dynamics, which prevents mitosis and induces apoptosis in tumor cells.
Nocodazole is a white powder. (NTP, 1992)
Nocodazole is a white powder. (NTP, 1992)|Nocodazole is a member of the class of benzimidazoles that is benzimidalole which is substituted at position 2 by a (methoxycarbonyl)amino group and at position 5 by a 2-thienoyl group. It is an antineoplastic agent that exerts its effect by depolymerising microtubules. It has a role as an antineoplastic agent, a tubulin modulator, an antimitotic and a microtubule-destabilising agent. It is a member of thiophenes, a member of benzimidazoles, a carbamate ester and an aromatic ketone.|Nocodazole is an antineoplastic agent which exerts its effect by depolymerizing microtubules.|Nocodazole is a synthetic tubulin-binding agent with antineoplastic activity. Nocodazole binds to beta-tubulin and disrupts microtubule assembly/disassembly dynamics. This prevents mitosis and induces apoptosis in tumor cells. Although nocodazole binding site overlaps with that of colchicine, the two agents are structurally quite different.Basic Info-
Product Name:
Nocodazole
Other Name:Carbamic acid,N-[6-(2-thienylcarbonyl)-1H-benzimidazol-2-yl]-,methyl ester;2-Benzimidazolecarbamic acid,5-(2-thenoyl)-,methyl ester;Carbamic acid,[5-(2-thienylcarbonyl)-1H-benzimidazol-2-yl]-,methyl ester;NSC 238159;R 17934;Oncodazole;N-[5-(2-Thenoyl)-2-benzimidazolyl]carbamic acid methyl ester;Nocodazole;Methyl[5-(2-thienylcarbonyl)-1H-benzimidazol-2-yl]carbamate;[6-(Thiophene-2-carbonyl)-1H-benzoimidazol-2-yl]-carbamic acid methyl ester;[5-(Thiophene-2-carbonyl)-1H-benzoimidazol-2-yl]-carbamic acid methyl ester;59697-13-1
CAS No.:31430-18-9
Molecular Formula:C14H11N3O3S
InChIKeys:InChIKey=KYRVNWMVYQXFEU-UHFFFAOYSA-N
Molecular Weight:301.32
Exact Mass:301.32
EC Number:250-626-5
UNII:SH1WY3R615
NSC Number:759882|238159
UN Number:2811
DSSTox ID:DTXSID9031800
NCI Thesaurus Code:C75228
HScode:2934999090
Categories:
Characteristics-
PSA:
112
XLogP3:2.8
Appearance:white powder
Density:1.5±0.1 g/cm3
Melting Point:300 °C (dec.)
Refractive Index:1.732
Water Solubility:DMSO: 10 mg/mL, soluble
Storage Conditions:2-8°C
Toxicity:sln-smc 1 ppm/16H MUREAV 141,15,84
Collision Cross Section:168.7 Ų [M+H]+ [CCS Type: TW, Method: calibrated with polyalanine and drug standards]
Air and Water Reactions:Insoluble in water.
Reactive Group:Amines, Phosphines, and Pyridines
Reactivity Profile:NOCODAZOLE may be sensitive to heat. (NTP, 1992).
Hazard IdentificationClassification of the substance or mixture
Germ cell mutagenicity, Category 2
Reproductive toxicity, Category 2
GHS label elements, including precautionary statements
Pictogram(s) 
Signal word Warning
Hazard statement(s) H341 Suspected of causing genetic defects
H361 Suspected of damaging fertility or the unborn child
Precautionary statement(s) Prevention P203 Obtain, read and follow all safety instructions before use.
P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...
Response P318 IF exposed or concerned, get medical advice.
Storage P405 Store locked up.
Disposal P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.
Other hazards which do not result in classification
no data available
Handling and StoragePrecautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.
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Seller Information
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Business Type:
Manufactory
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Main Products:
Cosmetics raw materials,Pesticide intermediate,Photoelectric material,pharmaceutical intermediates,Raw materials for food and health products,Polymer materials
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Location:
D307, Zhuque Square Office Building, No. 14, Chang'an North Road, Beilin District, Xi'an City, Shaanxi Province
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Payment Terms:
TT against copy of documents,TT against B/L draft before shipment,100% TT in advance
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Average lead Time:
45 days
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Total Annual Revenue:
Less than $1 million
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Total Employees:
11-50
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Year of Establishment:
2023
Company Certificates-
ISO
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ISO
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ISO
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Country Product Purchase Quantity Date Posted Post an enquiry for this product
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