Cycloleucine Manufacturer/High quality/Best price/In stock
52-52-8
98%
according to the clients requirement
2024-12-31
N-Diethyl-m-toluamide,6-Methyluracil,Anisole,4-Dimethoxybenzoic acid,CS (lacrimator),Daucosterol
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Product Description
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Seller Information
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DescriptionKeywords
Competitive price/ Top quality of Cycloleucine
global trader Offer Reliable quality of Cycloleucine
Best price of 99%m in Cycloleucine
Quick DetailsProName:Cycloleucine Manufacturer/High quality/Best price/In stock
CasNo:52-52-8
Molecular Formula:C6H11NO2
Appearance:detailed see specifications
Application:It is an important raw material and intermediate used in Organic Synthesis, Pharmaceuticals, Agrochemicals and Dyestuff.
DeliveryTime:prompt
PackAge:according to the clients requirement
Port:Shanghai
ProductionCapacity:1-100 Metric Ton/Month
Purity:98%
Storage:Store in dry, dark and ventilated place.
Transportation:by sea or by air
LimitNum:1 Kilogram
SuperiorityDayangchem's R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. DayangChem can provide different quantities of custom synthesis chemicals in lab, plant and industrial scale with more than fifteen years.
Pls contact with us freely for getting detailed product specifications, product tech. date sheet, COA and MSDS, prices, delivery time and payment terms.
DayangChem exported this product to many countries and regions at best price in China. If you are looking for the product's supplier in China, Dayangchem is your best choice.
Details
Dayang Chem (Hangzhou) Co.Limited, established in 2000, dedicated to the development, production and marketing of chemicals. We are a leading manufacturer and supplier of chemicals in China.
Manufacturing base: The Company has some Manufacturing base in Zhejiang, Jiangsu and Shandong provide. These bases focus on production and Contract Manufacturing.
Strong quality control system: Strength of our ethical commitment to quality control and quality assurance systems firmly based on ISO standard. QA and QC used in the whole process of raw material control, process control and finished product quality inspection.
Sales agent: Dayangchem are authorized by many Chinese chemical manufacturers as universal agency and international area agency. Dayangchem has established very good cooperation and business relations with hundreds of Chinese qualified manufacturers by long time business intercourse.
Rich experience in sales: 1000 square meters of office space with independent property rights, Sales team of nearly 40 people. Our customers throughout the world, especially the world-renowned companies, such as BACHEM, BASF, CELANESE, CORDEN,DOW,EVONIK, GENZYME,HENKEL, MERCK,ROCHE,SANOFI,SOLVAY.
Flexible payment terms: Various payment terms such as L/C,D/P,D/A and T/T will be accepted. Special Notice: DAYANGCHEM never require customers to remit payment to a personal account. Beware of being cheated.
ECHEMI Editorial ReferenceWHITE TO BEIGE CRYSTALLINE FLAKES OR POWDER
1-aminocyclopentanecarboxylic acid is a non-proteinogenic alpha-amino acid that is cyclopentane substituted at position 1 by amino and carboxy groups. It has a role as an EC 2.5.1.6 (methionine adenosyltransferase) inhibitor.|Cycloleucine is non-metabolisable amino acid formed by cyclization of leucine. It is also a specific and reversible inhibitor of nucleic acid methylation and widely used in biochemical experiments.|Cycloleucine is a non-metabolizable synthetic amino acid, formed through the cyclization of the amino acid leucine, with immunosuppressive, antineoplastic, and cytostatic activities. Cycloleucine competitively inhibits the enzyme methionine adenosyltransferase, resulting in the inhibition of S-adenosylmethionine (SAM) synthesis from methionine and ATP, and subsequent nucleic acid methylation and polyamine production; RNA, and perhaps to a lesser extent, DNA biosyntheses and cell cycle progression are finally disrupted. This agent is also a competitive inhibitor at the glycine modulatory site of the N-methyl-D-aspartate (NMDA) receptor.|An amino acid formed by cyclization of leucine. It has cytostatic, immunosuppressive and antineoplastic activities.
ChEBI: A non-proteinogenic alpha-amino acid that is cyclopentane substituted at position 1 by amino and carboxy groups.
Cycloleucine is a nonmetabolizable amino acid widely used as a building block in peptide synthesis.
Any Cl -or other anions are removed by stirring with a strong cation exchange resin (Amberlite IR-120), filtering, and washing with distilled H2O until the filtrate is free from the anion. The resin is then stirred overnight with 6N NH4OH, filtered, the filtrate is decolourised (charcoal) and evaporated to dryness in a vacuum. The residue is recrystallised from H2O/EtOH. Also crystallise it from aqueous EtOH. The hydrochloride has m 222-224o(dec). [Neelakantan & Hartung J Org Chem 23 967 1958, Connors & Ross J Chem Soc 2119 1960. O’Donnell et al. Synthesis 127 1984, Beilstein 14 IV 974.]Basic Info-
Product Name:
Cycloleucine
Other Name:RARECHEM AK HD C019;TIMTEC-BB SBB004230;1-amino-cyclopentanecarboxylicaci;Amino-1-cyclopentanecarboxylic acid;CB 1639;cb1639;Cycloleucin;Cyclopentanecarboxylic Acid, 1-amino-, L-
CAS No.:52-52-8
Molecular Formula:C6H11NO2
InChIKeys:NILQLFBWTXNUOE-UHFFFAOYSA-N
Molecular Weight:129.16
Exact Mass:129.16
BRN:636626
EC Number:200-144-6
UNII:0TQU7668EI
NSC Number:1026
TSCA:TSCA listed
DSSTox ID:DTXSID5024475
NCI Thesaurus Code:C404
Color/Form:White to beige
HScode:29224999
Categories:
Characteristics-
PSA:
63.3
XLogP3:-2.6
Appearance:White to beige Crystalline Flakes or Powder
Density:1.1426 (rough estimate)
Melting Point:320 °C (dec.) (lit.)
Boiling Point:239.22°C (rough estimate)
Flash Point:108.7±22.6 °C
Refractive Index:1.4827 (estimate)
Water Solubility:5 g/100 mL
Storage Conditions:Store at RT.
Toxicity:LD50 oral in rat: 290mg/kg
Flammability characteristics:Flammable; burning produces toxic nitrogen oxide fumes
PKA:2.38±0.20(Predicted)
Dissociation Constants:2.62
Experimental Properties:MP 274 °C, DECOMP; PRISMIC CRYSTALS FROM WATER /HYDROCHLORIDE/
Critical Temperature & Pressure:Keep in dark place,Inert atmosphere,Room temperature
Hazard IdentificationClassification of the substance or mixture
Acute toxicity - Category 3, Oral
GHS label elements, including precautionary statements
Pictogram(s) 
Signal word Danger
Hazard statement(s) H301 Toxic if swallowed
Precautionary statement(s) Prevention P264 Wash ... thoroughly after handling.
P270 Do not eat, drink or smoke when using this product.
Response P301+P316 IF SWALLOWED: Get emergency medical help immediately.
P321 Specific treatment (see ... on this label).
P330 Rinse mouth.
Storage P405 Store locked up.
Disposal P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.
Other hazards which do not result in classification
no data available
Handling and StoragePrecautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.
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Seller Information
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Business Type:
Manufactory
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Main Products:
N-Diethyl-m-toluamide,6-Methyluracil,Anisole,4-Dimethoxybenzoic acid,CS (lacrimator),Daucosterol
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Location:
RM901-7,Unit 2,259# WenSan Road, Xihu District, Hangzhou Zhejiang, China
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Payment Terms:
TT against copy of documents,D/P,L/C,D/A,TT against B/L draft before shipment,100% TT in advance
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Average lead Time:
2 days
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Total Annual Revenue:
$10 million-$25 million
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Total Employees:
11-50
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Year of Establishment:
2020
Company Certificates-
Dangerous Chemicals Business License
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Pesticide Business License
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ISO 9001:2015
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Country Product Purchase Quantity Date Posted Post an enquiry for this product
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