Bendamustine hydrochloride Manufacturer/High quality/Best price/In stock
3543-75-7
99%
according to the clients requirement
Yes
2024-12-31
N-Diethyl-m-toluamide,6-Methyluracil,Anisole,4-Dimethoxybenzoic acid,CS (lacrimator),Daucosterol
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Product Description
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Seller Information
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DescriptionKeywords
Bendamustine hydrochloride supplier in China
Bendamustine hydrochloride Competitive price
Bendamustine hydrochloride exporter in China
Quick DetailsProName:Bendamustine hydrochloride Manufacturer/High quality/Best price/In stock
CasNo:3543-75-7
Molecular Formula:C16H22Cl3N3O2
Appearance:white crystalline powder
Application:It is an important raw material and intermediate used in Organic Synthesis, Pharmaceuticals, Agrochemicals and Dyestuff.
DeliveryTime:prompt
PackAge:according to the clients requirement
Port:Shanghai
ProductionCapacity:1-100 Metric Ton/Month
Purity:99%
Storage:Store in dry, dark and ventilated place.
Transportation:by sea or by air
LimitNum:1 Kilogram
SuperiorityDayangchem's R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. DayangChem can provide different quantities of custom synthesis chemicals in lab, plant and industrial scale with more than fifteen years.
Pls contact with us freely for getting detailed product specifications, product tech. date sheet, COA and MSDS, prices, delivery time and payment terms.
DayangChem exported this product to many countries and regions at best price in China. If you are looking for the product's supplier in China, Dayangchem is your best choice.
Details
Dayang Chem (Hangzhou) Co. Limited, established in 2000, dedicated to the development, production and marketing of chemicals. We are a leading manufacturer and supplier of chemicals in China.
Manufacturing base: The Company has some Manufacturing base in Zhejiang, Jiangsu and Shandong provide. These bases focus on production and Contract Manufacturing.
Strong quality control system: Strength of our ethical commitment to quality control and quality assurance systems firmly based on ISO standard. QA and QC used in the whole process of raw material control, process control and finished product quality inspection.
Third lab test: Audit directly and tested by third party like SGS or INTERTEK in any time will be accepted under required.
Sales agent: Dayangchem are authorized by many Chinese chemical manufacturers as universal agency and international area agency. Dayangchem has established very good cooperation and business relations with hundreds of Chinese qualified manufacturers by long time business intercourse.
Flexible payment terms: Various payment terms such as L/C,D/P,D/A and T/T will be accepted. Special Notice: DAYANGCHEM never require customers to remit payment to a personal account. Beware of being cheated.
Rich experience in sales: 1000 square meters of office space with independent property rights, Sales team of nearly 40 people. Our customers throughout the world, especially the world-renowned companies, such as BACHEM, BASF, CELANESE, CORDEN,DOW,EVONIK, GENZYME,HENKEL, MERCK,ROCHE,SANOFI,SOLVAY.
ECHEMI Editorial ReferenceBendamustine hydrochloride is a DNA cross-linking agent that causes DNA breaks, with alkylating and antimetabolite properties.
Bendamustine is a parenterally administered alkylating agent used alone and in combination with other antineoplastic agents in the treatment of chronic lymphocytic leukemia and refractory forms of non-Hodgkin lymphoma. Bendamustine therapy is associated with minor transient serum enzyme elevations during treatment and to rare instances of clinically apparent liver injury, with jaundice generally arising as a part of a generalized hypersensitivity syndrome. Bendamustine also has potent immunosuppressive activity and can cause reactivation of chronic hepatitis B that can be severe and even fatal.|Bendamustine Hydrochloride is the hydrochloride salt of bendamustine, a bifunctional mechlorethamine derivative with alkylator and antimetabolite activities. Bendamustine possesses three active moieties: an alkylating group; a benzimidazole ring, which may act as a purine analogue; and a butyric acid side chain. Although its exact mechanism of action is unknown this agent appears to act primarily as an alkylator. Bendamustine metabolites alkylate and crosslink macromolecules, resulting in DNA, RNA and protein synthesis inhibition, and, subsequently, apoptosis. Bendamustine may differ from other alkylators in that it may be more potent in activating p53-dependent stress pathways and inducing apoptosis; it may induce mitotic catastrophe; and it may activate a base excision DNA repair pathway rather than an alkyltransferase DNA repair mechanism. Accordingly, this agent may be more efficacious and less susceptible to drug resistance than other alkylators.|A nitrogen mustard compound that functions as an ALKYLATING ANTINEOPLASTIC AGENT and is used in the treatment of CHRONIC LYMPHOCYTIC LEUKEMIA and NON-HODGKIN'S LYMPHOMA.Basic Info-
Product Name:
Bendamustine hydrochloride
Other Name:1H-Benzimidazole-2-butanoic acid,5-[bis(2-chloroethyl)amino]-1-methyl-,hydrochloride (1:1);2-Benzimidazolebutyric acid,5-[bis(2-chloroethyl)amino]-1-methyl-,monohydrochloride;1H-Benzimidazole-2-butanoic acid,5-[bis(2-chloroethyl)amino]-1-methyl-,monohydrochloride;IMET 3393;Cytostasan;ZIMET 33/93;Bendamustin hydrochloride;Bendamustine hydrochloride;Ribomustin;SDX 105;Treanda;Bendit;Purplz
CAS No.:3543-75-7
Molecular Formula:C16H21Cl2N3O2.ClH
InChIKeys:InChIKey=ZHSKUOZOLHMKEA-UHFFFAOYSA-N
Molecular Weight:394.72
Exact Mass:393.077759
EC Number:1592732-453-0
UNII:981Y8SX18M
NSC Number:138783
DSSTox ID:DTXSID40188912
NCI Thesaurus Code:C61565
HScode:29339900
Categories:
Characteristics-
PSA:
58.4
XLogP3:4.06660
Appearance:off-white
Melting Point:148-151 °C
Water Solubility:H2O: >30mg/mL
Storage Conditions:Desiccate at RT
Toxicity:LD50 (monohydrate) in mice, rats (mg/kg): 400-500, 200-300 orally; 80, 40 i.v. (Horn)
Hazard IdentificationClassification of the substance or mixture
Acute toxicity - Category 3, Oral
Carcinogenicity, Category 2
Reproductive toxicity, Category 1B
GHS label elements, including precautionary statements
Pictogram(s) 
Signal word Danger
Hazard statement(s) H301 Toxic if swallowed
H351 Suspected of causing cancer
H360 May damage fertility or the unborn child
Precautionary statement(s) Prevention P264 Wash ... thoroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P203 Obtain, read and follow all safety instructions before use.
P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...
Response P301+P316 IF SWALLOWED: Get emergency medical help immediately.
P321 Specific treatment (see ... on this label).
P330 Rinse mouth.
P318 IF exposed or concerned, get medical advice.
Storage P405 Store locked up.
Disposal P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.
Other hazards which do not result in classification
no data available
Handling and StoragePrecautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.
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Seller Information
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Business Type:
Manufactory
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Main Products:
N-Diethyl-m-toluamide,6-Methyluracil,Anisole,4-Dimethoxybenzoic acid,CS (lacrimator),Daucosterol
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Location:
RM901-7,Unit 2,259# WenSan Road, Xihu District, Hangzhou Zhejiang, China
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Payment Terms:
TT against copy of documents,D/P,L/C,D/A,TT against B/L draft before shipment,100% TT in advance
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Average lead Time:
2 days
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Total Annual Revenue:
$10 million-$25 million
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Total Employees:
11-50
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Year of Establishment:
2020
Company Certificates-
Dangerous Chemicals Business License
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Pesticide Business License
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ISO 9001:2015
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Country Product Purchase Quantity Date Posted Post an enquiry for this product
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