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High Quality Bendamustine hydrochloride

Unit Price: Get Latest Price
CAS No.:

3543-75-7

Grade:

Pharmaceutical Grade

Content:

99.5%

Port:

Hangzhou

Brand:

HyperChem

Packaging:

1kg/Bag

Price valid (until):

2025-04-21

Company Type:
Trader
Location:
China
Qualification:
Main Products:

Pharmaceuticals,Peptide,Cosmetics,Nutritional Supplements

  • Product Description

  • Seller Information

  • Description

    Name

    Bendamustine

    CAS number

    3543-75-7

    Synonym

    SDX105; SDX 105; SDX-105; DD6304600; Bendamustine HCl

    Description

    Bendamustine hydrochloride is the hydrochloride salt of bendamustine, a bifunctional mechlorethamine derivative with alkylator and antimetabolite activities. Bendamustine possesses three active moieties: an alkylating group; a benzimidazole ring, which may act as a purine analogue; and a butyric acid side chain. Although its exact mechanism of action is unknown, this agent appears to act primarily as an alkylator. Bendamustine metabolites alkylate and crosslink macromolecules, resulting in DNA, RNA and protein synthesis inhibition, and, subsequently, apoptosis. 

    Structure

    Shop High Quality Lincomycin CAS 154-21-2 Powder Fast Shipping Good Price-Detailed Image 1

    Molecular Formula

    C16H22Cl3N3O2

    Molecular Weight

    394.72 g/mol

    Appearance

    White Powder

    Quality Standard

    99%

    Shipping Condition

    Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

    Storage Condition

    Dry, dark and at 2~8 for short term (days to weeks) or -20 for long term (months to years).

    Shelf Life

    >2 years if stored properly

    Sample package

    Aluminium foil bag, Bottle

    Commercial package

    Aluminium Tin

    Origin

    China

    Bendamustine HCL More Info

    Bendamustine HCl is a chemotherapy medication used to treat certain types of cancer. Here is a detailed overview:

    Classification:

    Bendamustine is classified as an alkylating agent. It works by interfering with the replication of cancer cells, thereby slowing or stopping their growth and spread.

    Uses:

    Chronic Lymphocytic Leukemia (CLL) : Used in the treatment of CLL, a type of cancer that affects a particular kind of white blood cell.

    Non-Hodgkin's Lymphoma (NHL) : Specifically effective in certain types of indolent (slow-growing) NHL.

    It may be used off-label for other types of cancers as determined by healthcare professionals.

    Administration:

    Bendamustine is administered intravenously, typically in a clinic or hospital setting. The dosage and schedule depend on the specific condition being treated and other individual patient factors.

    Dosage:

    The typical regimen might involve administration on certain days of a cycle followed by a rest period. Specific dosing schedules should be strictly followed as prescribed by an oncologist.

    Side Effects:

    Common side effects include nausea, vomiting, fatigue, fever, and diarrhea.

    There may also be more serious side effects such as myelosuppression (decreased bone marrow activity leading to reduced blood cell production), an increased risk of infections, infusion reactions, and skin reactions.

    Long-term use or high doses may increase the risk of developing secondary malignancies.

    Precautions:

    Careful monitoring is required during treatment, including blood tests to monitor blood cell counts.

    Not recommended for use in patients with severe liver or kidney impairment without specialist consultation.

    Potential risks during pregnancy and breastfeeding, so effective contraception should be used during treatment and for some time afterward.

    Interactions:

    Bendamustine may interact with other medications, including live vaccines and other cancer treatments. Patients should provide their healthcare provider with a complete list of medications and supplements they are taking.

    Monitoring and Support:

    Patients undergoing treatment with bendamustine require regular monitoring by their healthcare provider to manage side effects and adjust treatment as needed.

    Supportive care, including medications to manage nausea or anemia, may be necessary during treatment.

    Bendamustine HCl is a critical medication in the treatment of certain cancers, offering hope for patients with conditions like CLL and NHL. Its use demands careful medical oversight to optimize treatment outcomes and safety.


    Product Image

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    FAQ


    Q1. Can I get a free sample?

    We can send you a samll free sample, and you only need to pay for the shipping cost.

     

    Q2. What is the HyperChem payment term?

    T/T in advance
    LC at sight
    DP at sight

    Bank transfer

    PayPal

    Bitcoin...

     

    Q3. What is HyperChem shipment policy?

    Our policy is to strive for the quickest shipment time possible.

    For ready stock samples, they are usually shipped within 3 working days after payment received.
    For non-ready stock, please contact HyperChem sales team to negotiate.

     

    Q4. What is HyperChem shipment term?

    By Express  
    FedEx  UPS  DHL  EMS                               
    Fast: 3-7 days around, high cost, door to door service

    By Air                                        
    Suitable for more than 50kg 
    Fast: 3-7 days, hight cost, port to port, professional broker needed 

    By Sea
    Suitable for more than 500kg      
    Fast: 7-45 days, low cost, port to port, professional broker needed 

     

    We will always attempt to utilize the quickest and most affordable way for customers to receive orders. And follow -up with customers via email for all shipment details as well as updated track information until it arrives without damage.

     

    Q5. What HyperChem will provide after shipment?

    For sample orders: 
    After shipment is done, an timely email including:

    1. Track details (Fedex /TNT/DHL/EMS Track number)
    2. Packaging photo
    3. COA, MSDS, etc
    4. Dispatch date & Estimated arriving time
    5. Shipping invoice

    For commercial orders:
    A full set of shipment documents as well as package photos can be provided in scan-copy and original, to help customers complete the customs clearance process.

    Basic Info
    Product Name:

    Bendamustine hydrochloride

    Other Name:

    1H-Benzimidazole-2-butanoic acid,5-[bis(2-chloroethyl)amino]-1-methyl-,hydrochloride (1:1);2-Benzimidazolebutyric acid,5-[bis(2-chloroethyl)amino]-1-methyl-,monohydrochloride;1H-Benzimidazole-2-butanoic acid,5-[bis(2-chloroethyl)amino]-1-methyl-,monohydrochloride;IMET 3393;Cytostasan;ZIMET 33/93;Bendamustin hydrochloride;Bendamustine hydrochloride;Ribomustin;SDX 105;Treanda;Bendit;Purplz

    CAS No.:

    3543-75-7

    Molecular Formula:

    C16H21Cl2N3O2.ClH

    InChIKeys:

    InChIKey=ZHSKUOZOLHMKEA-UHFFFAOYSA-N

    Molecular Weight:

    394.72

    Exact Mass:

    393.077759

    EC Number:

    1592732-453-0

    UNII:

    981Y8SX18M

    NSC Number:

    138783

    DSSTox ID:

    DTXSID40188912

    NCI Thesaurus Code:

    C61565

    HScode:

    29339900

    Categories:

    Other Chemical Drugs

    Characteristics
    PSA:

    58.4

    XLogP3:

    4.06660

    Appearance:

    off-white

    Melting Point:

    148-151 °C

    Water Solubility:

    H2O: >30mg/mL

    Storage Conditions:

    Desiccate at RT

    Toxicity:

    LD50 (monohydrate) in mice, rats (mg/kg): 400-500, 200-300 orally; 80, 40 i.v. (Horn)

    Hazard Identification

    Classification of the substance or mixture

    Acute toxicity - Category 3, Oral

    Carcinogenicity, Category 2

    Reproductive toxicity, Category 1B

    GHS label elements, including precautionary statements

    Pictogram(s)
    Signal word

    Danger

    Hazard statement(s)

    H301 Toxic if swallowed

    H351 Suspected of causing cancer

    H360 May damage fertility or the unborn child

    Precautionary statement(s)
    Prevention

    P264 Wash ... thoroughly after handling.

    P270 Do not eat, drink or smoke when using this product.

    P203 Obtain, read and follow all safety instructions before use.

    P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...

    Response

    P301+P316 IF SWALLOWED: Get emergency medical help immediately.

    P321 Specific treatment (see ... on this label).

    P330 Rinse mouth.

    P318 IF exposed or concerned, get medical advice.

    Storage

    P405 Store locked up.

    Disposal

    P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.

    Other hazards which do not result in classification

    no data available

    Handling and Storage

    Precautions for safe handling

    Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

    Conditions for safe storage, including any incompatibilities

    Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

  • Seller Information
    Business Type:

    Trader

    Main Products:

    Pharmaceuticals,Peptide,Cosmetics,Nutritional Supplements

    Location:

    Rm. 803, Tower 4, LOFT49 Creative City Pioneer Zone, No.88 Jiru Rd. Gongshu Dist., Hangzhou, 310015 ZJ, China

    Payment Terms:

    TT against copy of documents,D/P,L/C,D/A,O/A,TT against B/L draft before shipment,100% TT in advance

    Average lead Time:

    10

    Total Annual Revenue:

    $5 million-$10 million

    Total Employees:

    11-50

    Year of Establishment:

    2013

    Certifications:

    Certification Report by Bureau Veritas

    About HyperChem

    Established in 2013, Hyper Chem has exclusive tie-ups with leading manufacturers, supplying raw materials produced in GMP and ISO 9002 certified facilities, and provides high-quality ingredients and raw materials to meet the needs of a diverse range of pharmaceutical cosmetics ingredients and nootropic supplements companies worldwide.

    Our Competitiveness

    One-stop supply

    Wide Range Of products including pharmaceutical, Cosmetic Ingredients and nootropic supplements

    Among all the pharmaceuticals,

    90% of them with GMP certificates,

    85% of them with DMF files and

    50% of them passed FDA approval,

    30% get CEP certificate

    20% are new R&D products.

    Custom Repackaging Service


    We can efficiently repackage your material into sample sizes, custom batch-specific sizes, or semi-bulk package sizes according to your specifications. And ensures the product is packaged in a quality-controlled environment and will maintain its integrity throughout every stage of the process.

    Quality Control/Quality Assurance


    HyperChem is committed to delivering on its promises of top-quality products with verified quality data.

    All materials are vigorously inspected by the factory and/or outsourced analytical laboratories to ensure each and every lot meets or exceeds our reference standards.

    Trade assurance service with 100% payment protection, It is best achieved by delivering products and services 100% right the first time, on time, every time.

    Professional

    Transparent Communication

    Fast Reaction,

    Professional Suggestion

    Beyond Expectation.

    We have exclusive partnerships with research and production facilities across the country and we offer varied pharmaceutical services in the most cost-efficient way. The production facilities are GMP, WHO-GMP, EU GMP and US FDA approved and are backed by strong regulatory support such as Dossier, DMF, Tech Pack and relevant Stability studies for regulatory filings.

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