L-carnitine

Carnitine is a B vitamin whose structure is like an amino acid, so some people classify it as an amino acid. Its main role is to help transport long-chain fatty acids to provide energy. This prevents fat from accumulating in the heart, liver and skeletal muscles. There are three forms of synthetic carnitine: left-handed, right-handed and racemic, and the effect of L-carnitine is better. L-carnitine is a compound with various physiological functions, the main function of which is to promote β-oxidation of fatty acids. It can also regulate the ratio of acyl groups in mitochondria and affect energy metabolism. L-carnitine can participate in the transport of branched-chain amino acid metabolites, thus promoting the normal metabolism of branched-chain amino acids. In addition, L-carnitine plays a role in the elimination and utilization of ketone bodies, which can be used as a biological antioxidant to remove free radicals, maintain the stability of the membrane, and improve the immunity of animals and the ability to resist disease and stress. Recent studies have shown that L-carnitine and acetyl-L-carnitine play an important role as carriers of energy metabolism in sperm mitochondria, clearing ROS and protecting sperm membrane function. Oral administration of L-carnitine and acetyl-L-carnitine can increase the total number of forward motile sperm and motile sperm, and improve the clinical pregnancy rate of women, and it is safe and effective. Clinical experimental studies at home and abroad have shown that carnitine treatment of male infertility is a new breakthrough in the field of male infertility drug treatment in recent years, and it is very necessary to further study its mechanism of action and clarify its indications.