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Home > Active Pharmaceutical Ingredients > Vitamins and Minerals Medicines > Biotin for Sale > China Most Professional Factory Supply High Qulity D-BIOTIN(Vitamin B7) CAS 58-85-5
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China Most Professional Factory Supply High Qulity D-BIOTIN(Vitamin B7) CAS 58-85-5

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Unit Price: Get Latest Price
CAS No.:

58-85-5

Grade:

Pharmaceutical Grade

Content:

99%

Port:

Shanghai

Brand:

Leader

Packaging:

25KG/Drum

Price valid (until):

2024-01-04

Company Type:
Manufactory
Location:
China
Qualification:
Main Products:

Biochemicals Ingredients,Vitamin Amino Acid Ingredients,Cosmestic Ingredients,Pharma Chemicals,Organic Fine Chemicals,Food Nutrient Ingredients

  • Product Description

  • Seller Information

  • Inquiry History

  • Description


      About Product Technical Details  


    D-Biotin Chemical Properties
    Melting point  231-233 °C(lit.)
    alpha  89 º (c=1, 0.1N NaOH)
    Boiling point  573.6±35.0 °C(Predicted)
    density  1.2693 (rough estimate)
    refractive index  90.5 ° (C=2, 0.1mol/L NaOH)
    storage temp.  -20°C
    solubility  H2O: 0.2 mg/mL Solubility increases with addition of 1 N NaOH.
    form  powder
    pka 4.74±0.10(Predicted)
    color  White crystalline powder or fine long needles
    PH 4.5 (0.1g/l, H2O)
    optical activity [α]20/D +91±2°, c = 1% in 0.1 M NaOH
    Water Solubility  Soluble in hot water, dimethyl sulfoxide, alcohol and benzene.
    Sensitive  Light Sensitive
    Merck  14,1231
    BRN  86838
    Stability: Stable, but light sensitive. Incompatible with strong oxidizing agents, strong bases, strong acids, formaldehyde, chloramine-T, nitrous acid.
    InChIKey YBJHBAHKTGYVGT-ZKWXMUAHSA-N
    LogP 0.861 (est)
    CAS DataBase Reference 58-85-5(CAS DataBase Reference)
    NIST Chemistry Reference Biotin(58-85-5)
    EPA Substance Registry System Biotin (58-85-5)


      Product Pictures  



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      About Our Group


            Since 1996 when our factory was put into production to year of 2020, our group has successively invested in more than 52 factories with shares and subordinates.We focus on manufacture high quality raw materials and refined ingredients which is widely used at different industries areas like Pharm & chemicals industry, functional active ingredients industry, nutritional Ingredients industry, health care products industry, cosmetics industry,  pharmaceutical and refined food, feed, oil industry, natural plant ingredients industries, agriculture industry etcs to provide top quality of GMP standards products.

            All the invested factories' product lines cover API and intermediates, vitamins, amino acids, plant extracts, daily chemical products, cosmetics raw materials, nutrition and health care products, food additives, feed additives, essential oil products, fine chemical products and agricultural chemical raw materials And flavors and fragrances. Especially in the field of vitamins, amino acids, pharmaceutical raw materials and cosmetic raw materials, agriculture raw materials, we have more than 20 years of production and sales experience. All products meet the requirements of high international export standards and have been recognized by customers all over the world. Our manufacture basement & R&D center located in National Aerospace Economic & Technical Development Zone Xi`an Shaanxi China.

            Now not only relying on self-cultivation and development as well as maintains good cooperative relations with many famous research institutes and universities in China. Now, we have closely cooperation with Shanghai Institute of Organic Chemistry of Chinese Academy of Science, Beijing Institute of Material Medical of Chinese Academy of Medical Science, China Pharmaceutical University, Zhejiang University. Closely cooperation with them not only integrating Science and technology resources, but also increasing the R&D speed and improving our R&D power. Offering Powerful Tech supporting Platform for group development. Keep serve the manufacture and the market as the R&D central task, focus on the technical research.  Now there are 3 technology R & D platforms including biological extract, microorganism fermentation and chemical synthesis, and can independently research and develop kinds of difficult APIs and pharmaceutical intermediates.

           With the strong support of China State Institute of Pharmaceutical Industry (hereinafter short for CSIPI), earlier known as Shanghai Institute of Pharmaceutical Industry (SIPI), we have unique advantages in the R & D and industrialization of high-grade, precision and advanced products.  Now our Group technical force is abundant, existing staff more that 1000 people, senior professional and technical staff accounted for more than 50% of the total number of employees, including 15 PhD research and development personnel, 5 master′ S degree in technical and management personnel 9 people.

           We have advanced equipment like fermentation equipment and technology also extraction, isolation, purification, synthesis with rich production experience and strict quality control system, According to the GMP required, quickly transforming the R&D results to industrial production in time, it is our advantages and our products are exported to North and South America, Europe, Middle East, Africa, and other five continents and scale the forefront in the nation, won good international reputation.  

           We believe only good quality can bring good cooperation, quality is our key spirit during our production, we are warmly welcome clients and partner from all over the world contact us for everlasting cooperation, Leader will be your strong, sincere and reliable partner in China.



      Our Factories Production Lines  



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      Sales Team  


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    Certificates
    • China Most Professional Factory Supply High Qulity D-BIOTIN(Vitamin B7) CAS 58-85-5 Certificates 7

    Basic Info
    Product Name:

    Biotin

    Other Name:

    1H-Thieno[3,4-d]imidazole-4-pentanoic acid,hexahydro-2-oxo-,(3aS,4S,6aR)-;Biotin;1H-Thieno[3,4-d]imidazole-4-pentanoic acid,hexahydro-2-oxo-,[3aS-(3aα,4β,6aα)]-;(3aS,4S,6aR)-Hexahydro-2-oxo-1H-thieno[3,4-d]imidazole-4-pentanoic acid;Bioepiderm;Coenzyme R;Factor S;(+)-cis-Hexahydro-2-oxo-1H-thieno[3,4]imidazole-4-valeric acid;cis-(+)-Tetrahydro-2-oxothieno[3,4]imidazoline-4-valeric acid;Vitamin H;Vitamin B7;d-Biotin;(+)-Biotin;Factor S (vitamin);D(+)-Biotin;Bios II;D-Biotin;Meribin;Rovimix H 2;Lutavit H2;Biodermatin;NSC 63865;Vitamin I;Medebiotin;5-((3aS,4S,6aR)-2-Oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanoic acid;MD 1003;7: PN: KR2178813 SEQID: 7 claimed sequence;3672-05-7;15720-24-8;22879-79-4;58073-87-3

    CAS No.:

    58-85-5

    Molecular Formula:

    C10H16N2O3S

    InChIKeys:

    InChIKey=YBJHBAHKTGYVGT-ZKWXMUAHSA-N

    Molecular Weight:

    244.31

    Exact Mass:

    244.31

    EC Number:

    200-399-3

    UNII:

    6SO6U10H04

    DSSTox ID:

    DTXSID7022679

    NCI Thesaurus Code:

    C309

    Color/Form:

    Long, thin needles from water|Colorless, crystalline

    ATC Code:

    A - Alimentary tract and metabolism

    HScode:

    29362930

    Characteristics
    PSA:

    104

    XLogP3:

    0.3

    Appearance:

    White powder

    Density:

    1.42 g/cm3

    Melting Point:

    232 °C (decomp)

    Boiling Point:

    573.6ºC at 760 mmHg

    Flash Point:

    300.7ºC

    Refractive Index:

    90.5 ° (C=2, 0.1mol/L NaOH)

    Water Solubility:

    Soluble in hot water, dimethyl sulfoxide, alcohol and benzene.

    Storage Conditions:

    Capsules and Tablets: Store below 40 deg C (104 deg F), preferably between 15 and 30 deg C (59 and 86 deg F), unless otherwise specified by manufacturer.

    Vapor Pressure:

    1.07X10-8 mm Hg at 25 deg C (est)

    Toxicity:

    LD50 orally in Rabbit: > 2000 mg/kg

    Henrys Law Constant:

    Henry's Law constant = 1.1X10-16 atm-cu m/mol at 25 °C (est)

    Collision Cross Section:

    150.4 Ų [M+H]+ [CCS Type: DT, Method: single field calibrated with Agilent tune mix (Agilent)]|152.96 Ų [M-H]- [CCS Type: DT, Method: single field calibrated with Agilent tune mix (Agilent)]|154.16 Ų [M+H]+ [CCS Type: DT, Method: stepped-field]|164.45 Ų [M+Na]+ [CCS Type: DT, Method: stepped-field]|159.72 Ų [M-H]- [CCS Type: DT, Method: stepped-field]|149.7 Ų [M+H]+ [CCS Type: DT, Method: single field calibrated with ESI Low Concentration Tuning Mix (Agilent)]|160.1 Ų [M+K]+ [CCS Type: DT, Method: single field calibrated with ESI Low Concentration Tuning Mix (Agilent)]|159.9 Ų [M+Na]+ [CCS Type: DT, Method: single field calibrated with ESI Low Concentration Tuning Mix (Agilent)]|155.4 Ų [M-H]- [CCS Type: DT, Method: single field calibrated with ESI Low Concentration Tuning Mix (Agilent)]|152.9 Ų [M+Na-2H]- [CCS Type: DT, Method: single field calibrated with ESI Low Concentration Tuning Mix (Agilent)]|148 Ų [M+H]+ [CCS Type: TW, Method: calibrated with polyalanine and drug standards]|152.9 Ų [M-2H+Na]-

    Experimental Properties:

    Fine long needles. Melting point: 232-3 °C. pH 0.01% aq soln: 4.5. Isoelectric point pH: 3.5. Solubility in water, 2.20X10+2 mg/L at 25 °C. More sol in hot water and dil alkali; in 95% alc about 80 mg/100 ml at 25 °C; insol in other common org solvents. Specific optical rotation +91 deg at 21 °C (c=1, 0.1 N NaOH). The pure compd is stable to air and temp /Milk or liver biotin/|Water solutions are stable at 100 °C, and the dry substance is both thermostable and photostable. Biotin is unstable, however, in strong acids and alkaline solutions and in oxidizing agents.|Hydroxyl radical reaction rate constant = 4.0X10-11 cu cm/molec-sec at 25 °C (est)

    Hazard Identification

    Classification of the substance or mixture

    Not classified.

    GHS label elements, including precautionary statements

    Pictogram(s) No symbol.
    Signal word

    No signal word

    Hazard statement(s)

    none

    Precautionary statement(s)
    Prevention

    none

    Response

    none

    Storage

    none

    Disposal

    none

    Other hazards which do not result in classification

    no data available

    Handling and Storage

    Precautions for safe handling

    Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

    Conditions for safe storage, including any incompatibilities

    Capsules and Tablets: Store below 40 deg C (104 deg F), preferably between 15 and 30 deg C (59 and 86 deg F), unless otherwise specified by manufacturer.

  • Seller Information
    Business Type:

    Manufactory

    Main Products:

    Biochemicals Ingredients,Vitamin Amino Acid Ingredients,Cosmestic Ingredients,Pharma Chemicals,Organic Fine Chemicals,Food Nutrient Ingredients

    Location:

    National Aerospace Economic & Technical Development Zone,Chang'an,Xi'an,China

    Payment Terms:

    TT against copy of documents,D/P,L/C,D/A,O/A,TT against B/L draft before shipment,100% TT in advance

    Average lead Time:

    5

    Total Annual Revenue:

    $10 million-$25 million

    Total Employees:

    Above 1000

    Year of Establishment:

    2014

    Certifications:

    Level A of Tax Credit Registration Assessment by Government,Good Product Quality Management Certificate of Shanxi Province,China,Company Trade Union Qualification Certificate,Excellent Group Enterprise of Quality and credit in Shaanxi ProvinceChina,AAA TOP Credit Excellent Group Enterprise of Shanxi Province,China,FDA


    24 Hours Team Service

    Email

    info@leader-biogroup.com   

    Hot Line

    +86-029-68895030  

    +86-029-68569961  

    +86-029-68569962  

    Fax

    +86-029-68895030


    Leader Biochemical Group is a large leader incorporated industry manufacturers and suppliers of advanced refined raw materials From the year of 1996 when our factory was put into production to year of 2020, our group has successively invested in more than 52 factories Base with shares and subordinates.We focus on manufacture Pharm & chemicals, functional active ingredients, nutritional Ingredients, health care products, cosmetics, pharmaceutical and refined feed, oil, natural plant ingredients industries to provide top quality of GMP standards products.All the invested factories' product lines cover API and intermediates, vitamins, amino acids, plant extracts, daily chemical products, cosmetics raw materials, nutrition and health care products, food additives, feed additives, essential oil products, fine chemical products and agricultural chemical raw materials And flavors and fragrances. Especially in the field of vitamins, amino acids, pharmaceutical raw materials and cosmetic raw materials, we have more than 20 years of production and sales experience. All products meet the requirements of high international export standards and have been recognized by customers all over the world.

    • Our manufacture basement & R&D center located in National Aerospace Economic & Technical Development Zone Xi`an Shaanxi China. Now not only relying on self-cultivation and development as well as maintains good cooperative relations with many famous research institutes and universities in China. Now, we have closely cooperation with Shanghai Institute of Organic Chemistry of Chinese Academy of Science, Beijing Institute of Material Medical of Chinese Academy of Medical Science, China Pharmaceutical University, Zhejiang University. Closely cooperation with them not only integrating Science and technology resources, but also increasing the R&D speed and improving our R&D power. Offering Powerful Tech supporting Platform for group development. Keep serve the manufacture and the market as the R&D central task, focus on the technical research.

      Now there are 3 technology R & D platforms including biological extract, microorganism fermentation and chemical synthesis, and can independently research and develop kinds of difficult APIs and pharmaceutical intermediates. With the strong support of China State Institute of Pharmaceutical Industry (hereinafter short for CSIPI), earlier known as Shanghai Institute of Pharmaceutical Industry (SIPI), we have unique advantages in the R & D and industrialization of high-grade, precision and advanced products.

      Now our Group technical force is abundant, existing staff more that 1000 people, senior professional and technical staff accounted for more than 50% of the total number of employees, including 15 PhD research and development personnel, 5 master′ S degree in technical and management personnel 9 people. We have advanced equipment like fermentation equipment and technology also extraction, isolation, purification, synthesis with rich production experience and strict quality control system, According to the GMP required, quickly transforming the R&D results to industrial production in time, it is our advantages and our products are exported to North and South America, Europe, Middle East, Africa, and other five continents and scale the forefront in the nation, won good international reputation.

      We believe only good quality can bring good cooperation, quality is our key spirit during our production, we are warmly welcome clients and partner from all over the world contact us for everlasting cooperation, Leader will be your strong, sincere and reliable partner in China.

    • Process Capability :   It has more than 100 sets of multi-functional reaction reactors, such as 100l~6300l enamel, stainless steel, Hastelloy, etc. It can realize Grignard, coupling, bromination, Wittig reaction and other conventional reactions. There are microchannel reactor workshops, which can realize continuous production, energy conservation and emission reduction. It can realize high pressure, high vacuum rectification, ultra-low temperature (-80 ℃ ~-100 ℃), ultra-high temperature (300 ℃ ~400 ℃) and other special reactions. It can realize the customization and processing of customers' products.

                                      

        Factory Overview

                                                                                 Factory Production Lines

    Our Professional Lab

                               Factory Warehouse 

    Factory Logistics Departments

    GROUP HONOR

    Honor Name: Level A of Tax Credit Registration Assessment   
    Issued By:National Administration of Taxation & Shaanxi Tax Bureau   
    Authorised Date:2018-09-16  
    Description: National Administration of Taxation & Shaanxi Tax Bureau




    Honor Name: AAA TOP Credit Excellent Group Enterprise of Shanxi Province,China  
    Issued By:China Association of Shaanxi product Quality management Center   
    Authorised Date:2018-12-31  
    Description:AAA TOP Credit Excellent Group Enterprise of Shanxi Province,China



    Honor Name:Excellent Group Enterprise of Quality and credit in Shaanxi ProvinceChina

    Issued By: China Association of Shaanxi product Quality management Center

    Authorised Date:2018-12-31

    Description: Excellent Group Enterprise of Quality and Integrity in Shaanxi Province,China



    Honor Name: Products Patent Certificates


  • Inquiry History
    11 Inquiries
    Country Product Purchase Quantity Date Posted
    Brazil

    BIOTIN CAS 58-85-5

    5 KG Apr 1, 2026
    Egypt

    Vitamin B7 Biotin

    50.00 KG Jan 28, 2026
    India

    Biotine pure

    2.00 KG Jul 1, 2025
    Turkey

    D-BIOTIN ( VİT B7)

    0.05 KG Apr 16, 2025
    Romania

    Biotin (98%)

    100 KG Dec 6, 2024
    United Kingdom

    Biotin

    150.00 MT Sep 3, 2025
    Egypt

    Vitamin B7

    5 KG Dec 5, 2024
    Malaysia

    Vitamin H (D-Biotin)

    100 G Aug 21, 2024
    Kenya

    Boitin

    500 KG Oct 31, 2024
    Yemen

    D-Biotin

    1 KG Nov 7, 2023
    South Korea

    EDTA-2Na

    1 MT Sep 2, 2024
    Post an enquiry for this product
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